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Screening for cardiovascular risk by measuring blood levels of C-reactive protein should not be advocated

C-reactive protein (CRP) is released by the liver in response to inflammation related to an infection, injury, or conditions such as arthritis. Inflammation also has been associated with the cause and progression of cardiovascular disease, particularly in the build up of fatty deposits in the lining of arteries.

10 Oct 2005

Obese Zucker rat model shares the symptoms of obesity with a growing number of Americans

A mutant rat that mimics a 400-pound human is helping scientists understand early vascular changes that make walking a pain for more than 2 million Americans.

9 Oct 2005

PET imaging with FDG represents one of the most promising tools for diagnosis of Alzheimer's

Positron emission tomography (PET) imaging--with the radiotracer fluorodeoxyglucose (FDG)--is a promising tool in detecting Alzheimer's disease in patients who have mild cognitive impairment (MCI), according to a study reported in the October issue of the Society of Nuclear Medicine's Journal of Nuclear Medicine.

5 Oct 2005

High blood glucose levels early in pregnancy deprive the embryo of oxygen

The babies of women with diabetes are two to five times more likely to develop birth defects than offspring of women without the disease.

4 Oct 2005

Children enrolled in fitness-oriented gym classes showed greater loss of body fat

Overweight children who took part in lifestyle-focused, fitness-oriented gym classes showed significant improvement in body composition, fitness, and insulin levels, according to a study in the October issue of Archives of Pediatrics and Adolescent Medicine.

3 Oct 2005

Experimental radioactive compound can show images of heart damage up to 30 hours after a brief interruption of blood flow and oxygen

The discovery may help physicians in emergency rooms and in their offices determine whether a patient's chest pain, which may have subsided hours earlier, is related to heart disease or something else, such as indigestion.

27 Sep 2005

Smoking may increase the risk of developing diabetes

The surprising finding emerged when researchers examined the relationship between smoking and diabetes among participants in a major national study, the Insulin Resistance Atherosclerosis Study (IRAS).

26 Sep 2005

PET brain scans of a brain chemical messenger system may prove sensitive enough to help plan brain surgery for epilepsy

When drugs fail to control epilepsy, brain surgery is often the only remaining therapeutic option. However, identifying the correct spot for surgery has traditionally required a separate preliminary -- and inherently risky -- surgical procedure.

26 Sep 2005

Lowering blood sugar levels could reduce the risk of coronary heart disease

Lowering blood sugar levels could reduce the risk of coronary heart disease in both diabetics and non-diabetics, according to researchers at the Johns Hopkins Bloomberg School of Public Health and other institutions.

19 Sep 2005

Key cellular switch that controls glucose production in liver cells

In many patients with type 2 diabetes, the liver acts like a sugar factory on overtime, churning out glucose throughout the day, even when blood sugar levels are high. Scientists at the Salk Institute for Biological Studies discovered a key cellular switch that controls glucose production in liver cells.

12 Sep 2005

Strong social gradient in the metabolic syndrome

It is well documented that individuals with higher social status have lower risk of coronary heart disease (CHD). This is generally not explained by differences in lifestyle factors such as smoking and lack of exercise.

6 Sep 2005

Metabolic Syndrome, a map of the cardiovascular damage

The metabolic syndrome (MS) is a cluster of metabolic abnormalities with abdominal obesity (increased waist circumference) at its centre. Although all forms of obesity have a negative impact on human health, metabolic syndrome describes a set of particularly adverse biochemical changes accompanying (abdominal) obesity.

5 Sep 2005

Metabolic syndrome (MetS) in Europe

Previously, several different definitions for the metabolic syndrome (MetS) had been proposed and used by researchers. This resulted in confusion about the frequency of the MetS and its relationship with mortality.

5 Sep 2005

People with serious mental illness have higher rates of type 2 diabetes

...yet their knowledge of diabetes was generally poor and significantly lower than people without mental illness, according to a new study.

1 Sep 2005

MRSA risk doubled in critically ill patients with glucose in their airways

Critically ill patients with glucose in their airways seem to be at double the risk of picking up serious hospital acquired infections, including MRSA, suggests research in Thorax.

1 Sep 2005

Early life exposure to second-hand smoke can produce life-long respiratory problems

A new study finds early life exposure to second-hand smoke can produce life-long respiratory problems. The study of 35,000 adult non-smokers in Singapore found that those who lived with a smoker during childhood had more respiratory problems, including chronic cough.

30 Aug 2005

Molecular missing link between fasting and acute attacks of porphyria

A team of researchers has discovered a molecular missing link that helps explain why fasting brings on acute attacks of the genetic disease hepatic porphyria, according to a new report in the 26 August issue of the journal Cell.

29 Aug 2005

Call for closer examination of a metabolic syndrome

Two major health organizations in Europe and the United States are calling for closer examination of a syndrome that has been widely believed to predict the risk of developing heart disease, questioning whether it has been appropriately defined and whether it is in fact a syndrome at all.

25 Aug 2005

Study shows potential treatment for brain cancer

A compound that kills cancer can sneak past the blood brain barrier, which protects the brain from foreign substances, to do its work in fighting a particularly invasive brain cancer, according to a new Saint Louis University animal study published in the Proceedings of the National Academy of Sciences Online Early Edition the week of Aug. 22.

22 Aug 2005

A cell's energy level is critical to its survival

In an ongoing effort to fight disease by manipulating energy regulation of cells, a collaborative study led by Dartmouth Medical School (DMS) has demonstrated that cells lacking a tumor-suppressing kinase called LKB1 can still maintain healthy energy levels when they become stressed.

22 Aug 2005