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Novel treatment promises to be an effective cure for tuberculosis

Researchers in Belgium have uncovered a novel treatment that promises to be an effective cure for tuberculosis (TB). The respiratory disease has been experiencing a major global comeback due to the emergence of resistant strains of the bacteria that causes it and the spread of AIDS.

9 Jan 2005

Gene sequencing explains why natural bioremediation 'bug' has big appetite for chlorinated pollutants

"The born-to-dechlorinate bug" is what Cornell University researchers called Dehalococcoides ethenogenes Strain 195 when they found the bacterium obligingly detoxifying the pollutant PCE, or perchloroethylene (a chlorinated solvent used for dry cleaning), in sludge from an Ithaca, N.Y., sewage treatment plant.

6 Jan 2005

40-year tale of investigation and innovation into the challenge of hip implant failure

A remarkable story of how a new disease was inadvertently caused by successful medical treatment, ultimately understood, and eventually defeated by scientific innovation is being told a major player in the process.

22 Dec 2004

New compound Viprovex could save millions

The World Health Organization (WHO) and influenza experts worldwide are concerned that the recent appearance and widespread distribution of an avian influenza virus (Influenza A/H5N1) has the potential to ignite the next pandemic and potentially kill millions.

21 Dec 2004

European market for bone morphogenic proteins in spine fusion

High growth is forecast for novel technologies used either as adjuncts or as alternatives to current surgical procedures for the fusion of spinal vertebrae. Bone morphogenic proteins (BMP) - a new and innovative class of natural growth factors - represent amongst the most exciting of these niches.

20 Dec 2004

Discovery of new compound known as SP-4-84 could lead to improved chemotherapy treatments

The discovery of a new compound by Michigan State University researchers could lead to improved chemotherapy treatments for different types of cancers – potentially with fewer side effects.

20 Dec 2004

Scientists have identified a novel anti-tuberculosis (TB) compound

Scientists at Johnson & Johnson Pharmaceutical Research and Development have identified a novel anti-tuberculosis (TB) compound that works better and faster than the current standard of care in mouse models of TB infection.

14 Dec 2004

Molecular Achilles heel in the organism that causes pneumonia

Scientists have found a “molecular Achilles heel” in the organism that causes pneumonia, providing a target for the development of a new class of antibiotics that could eventually eradicate the disease.

13 Dec 2004

Lupus drug may also be useful in treating psoriasis

A new drug candidate previously shown to reduce harmful side effects of the autoimmune disease lupus also may be useful in treating psoriasis.

13 Dec 2004

Resveratrol antioxidant found in red wine may benefit heart tissue

New research on rat heart cells suggests that a well-known antioxidant found in red wine, called resveratrol, may benefit heart tissue by limiting the effects of a condition called cardiac fibrosis.

8 Dec 2004

Advanced wound care products to power expansion of European wound care market

The USD 1,111.1 million European wound care market is projected to gradually transition from traditional to advanced wound dressings. While traditional dressings currently dominate the total market, rising awareness of the clinical benefits provided by advanced wound dressings are set to widen their uptake.

7 Dec 2004

Escalating costs and lengthy clinical trials are major concerns for researchers in the field of drug discovery

Escalating costs and lengthy clinical trials are major concerns for researchers attempting to boost productivity and efficiency in the field of drug discovery. Biomarkers are emerging as the solution to these problems with their ability to reduce drug development costs and time.

7 Dec 2004

Common ingredient in some shampoos (methylisothiazolinone) stunts developing neurons of rats

An antimicrobial agent found in some shampoos and hand creams and widely used in industrial settings inhibits the development of particular neuron structures that are essential for transmitting signals between cells.

6 Dec 2004

New drug can successfully treat patients who have become resistant to Gleevec

A team of prominent researchers led by Charles Sawyers, M.D. and Moshe Talpaz, M.D., presented compelling clinical findings today showing that a new drug, BMS-354825, can successfully treat patients who have become resistant to Gleevec (the frontline therapy for chronic myelogenous leukemia, CML).

5 Dec 2004

Novel anti-obesity compound shows promise for treatment of obesity

Arena Pharmaceuticals announced today results from the dosing phase of its Phase 1b clinical trial of APD356, an orally administered small molecule designed to regulate satiety (and perhaps metabolism) for the treatment of obesity.

30 Nov 2004

Citrus fruits offer promise in fighting childhood cancer

Orange juice and cancer don't mix. In fact, the popular citrus drink could become a cocktail to prevent or stop the deadly disease in humans.

30 Nov 2004

Biopharmaceuticals industry, a rapidly growing sector within the pharmaceuticals industry

Global manufacturing of biopharmaceuticals has increased significantly over the last decade due to a number of reasons. Biopharmaceuticals offer several advantages such as highly effective and potent action, fewer side effects and the potential to actually cure diseases rather than merely treat the symptoms.

30 Nov 2004

Venom from one of the world’s deadliest snakes is being developed as a new drug to treat heart failure

“The team has isolated a unique set of active molecules from Taipan venom and research shows they are extremely effective at easing the heart’s workload,” he said.

29 Nov 2004

Indoprofen may lead to new treatments for spinal muscular atrophy

A drug withdrawn from pharmacy shelves over 20 years ago may point the way to a new treatment for spinal muscular atrophy, or SMA, a muscle-wasting and often life-threatening childhood disease.

29 Nov 2004

Rifampicin can prevent the formation of protein fibrils associated with Parkinson's disease

Researchers at the University of California, Santa Cruz, have shown that rifampicin, an antibiotic used to treat leprosy and tuberculosis, can prevent the formation of protein fibrils associated with the death of brain cells in people with Parkinson's disease. The drug also dissolved existing fibrils in laboratory tests.

29 Nov 2004

Compound News and Research

Novel treatment promises to be an effective cure for tuberculosis

Gene sequencing explains why natural bioremediation 'bug' has big appetite for chlorinated pollutants

40-year tale of investigation and innovation into the challenge of hip implant failure

New compound Viprovex could save millions

European market for bone morphogenic proteins in spine fusion

Discovery of new compound known as SP-4-84 could lead to improved chemotherapy treatments

Scientists have identified a novel anti-tuberculosis (TB) compound

Molecular Achilles heel in the organism that causes pneumonia

Lupus drug may also be useful in treating psoriasis

Resveratrol antioxidant found in red wine may benefit heart tissue

Advanced wound care products to power expansion of European wound care market

Escalating costs and lengthy clinical trials are major concerns for researchers in the field of drug discovery

Common ingredient in some shampoos (methylisothiazolinone) stunts developing neurons of rats

New drug can successfully treat patients who have become resistant to Gleevec

Novel anti-obesity compound shows promise for treatment of obesity

Citrus fruits offer promise in fighting childhood cancer

Biopharmaceuticals industry, a rapidly growing sector within the pharmaceuticals industry

Venom from one of the world’s deadliest snakes is being developed as a new drug to treat heart failure

Indoprofen may lead to new treatments for spinal muscular atrophy

Rifampicin can prevent the formation of protein fibrils associated with Parkinson's disease

Enhancing confidence in chemical ionization spectrometry data eBook

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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