Genomic News and Research

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Pharmacists play critical role in reducing medication discrepancies

Involving pharmacists in obtaining and assessing a patient's medication history before elective surgery can significantly reduce medication discrepancies upon hospital admission.

30 May 2007

Scientists develop a more human-like mouse model of cancer

A team led by Dana-Farber Cancer Institute scientists has developed a more human-like mouse model of cancer they say will aid the search for cancer-causing genes and improve the predictive value of laboratory drug testing.

28 May 2007

Tool will revolutionise functional genomic studies in clostridia

The genome of the organism that produces the world's most lethal toxin has been revealed.

24 May 2007

Peering into the body and visualizing its molecular secrets one step closer to reality

Peering into the body and visualizing its molecular secrets, once the stuff of science fiction, is one step closer to reality with a study from researchers at the Stanford University School of Medicine and the University of California, San Diego School of Medicine.

22 May 2007

In some species estrogen plays a key role in aggressiveness

Imagine if a naturally occurring chemical in your body could help make you feel more calm and relaxed ? but it would only work during the long days of summer.

22 May 2007

Decoding gene expression in cancer tumors using noninvasive imaging

By correlating images of cancerous liver tissue with gene expression patterns, a research team led by a radiologist at the University of California, San Diego (UCSD) School of Medicine has developed tools that may some day allow physicians to view a CT image of a cancer tumor and discern its genetic activity.

22 May 2007

First draft of the genome sequence of Aedes aegypti mosquito

Developing new strategies to prevent and control yellow fever and dengue fever has become more possible with the completion of the first draft of the genome sequence of Aedes aegypti mosquito by scientists led by Vishvanath Nene at The Institute for Genomic Research (TIGR) and David Severson at the University of Notre Dame.

18 May 2007

Researchers identify genetic markers associated with breast cancer tumor grade and lymph node metastases

Researchers have identified genetic markers on several chromosomes in the tissue surrounding tumor cells that are associated with breast cancer tumor grade and the presence of lymph node metastases, according to a study in the May 16 issue of JAMA.

16 May 2007

Protein findings establish better understanding of tumor development

Peter Baumann, Ph.D., Assistant Investigator, and Nancy Bae, Ph.D., Postdoctoral Research Associate in the Baumann Lab, have published a paper offering insight into the way cells protect chromosome ends from misguided repair.

11 May 2007

Discovery of cellular processes which regulate heart's energy supply

The heart needs a steady supply of energy to function properly. MUHC researcher Dr. Vincent Gigure's and his colleagues recently identified several genetic programs which work together to ensure this energy is available.

10 May 2007

Global heartbeat control suggests therapy for beating heart failure

Keeping a healthy heart beating requires the production of a constant supply of energy, a feat depending on the coordination of several genetic programs.

9 May 2007

Study looks at interest level of healthy, young adults in receiving genetic testing for common conditions

The National Human Genome Research Institute (NHGRI) and the National Cancer Institute (NCI), parts of the National Institutes of Health (NIH), have teamed with Group Health Cooperative in Seattle and Henry Ford Health System in Detroit to launch a study to investigate the interest level of healthy, young adults in receiving genetic testing for eight common conditions.

8 May 2007

New mapping technique will answer fundamental questions about chromosome structure

Researchers at the University of Illinois have developed a simple and economical technique for imaging and mapping fruit fly chromosomes.

8 May 2007

Renewal of Echinacea and St John's Wort research

A five-year-old research center dedicated to understanding and improving Echinacea and Hypericum perforatum (St. John's wort) has received $4.4 million in continuation funding from the National Institutes of Health. The renewal is for three years.

4 May 2007

New interactive map shows spread of avian flu virus

Scientists here have designed a new, interactive map of the spread of the avian flu virus (H5N1) that for the first time incorporates genetic, geographic and evolutionary information that may help predict where the next outbreak of the virus is likely to occur.

1 May 2007

Google maps used to track avian flu spread

An interactive "supermap" that portrays the mutations and spread of the avian flu around the globe over time should help researchers and policy makers better understand the virus and anticipate further outbreaks, according to a new study involving University of Colorado at Boulder and Ohio State University researchers.

1 May 2007

RNA analysis can identify rejection in lung transplant patients

Recent data from the Lung Allograft Rejection Gene expression Observational (LARGO) study provides compelling evidence that profiling gene expression in peripheral blood can detect organ rejection in lung transplant patients.

1 May 2007

World's first microRNA knockout mouse

A role for a microRNA in the immune system has been shown by study of one of the world's first microRNA knockout mouse, reported in Science.

27 Apr 2007

Researchers find clear genetic risk factors for type 2 diabetes

Scientists from the Broad Institute of Harvard and MIT, Lund University and Novartis have announced the discovery of three unsuspected regions of human DNA that contain clear genetic risk factors for type 2 diabetes, and another that is associated with elevated blood triglycerides.

27 Apr 2007

New searchable influenza gene database

A Medical College of Wisconsin and Children's Research Institute team in Milwaukee has created a free, searchable genetic database that will significantly improve diagnostic testing and genetic tracking of human and animal influenza viruses.

26 Apr 2007