Mutation News and Research

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Findings set the stage for identifying potential new drug targets, treatment strategies for AML

nvestigators for The Cancer Genome Atlas Research Network have detailed and broadly classified the genomic alterations that frequently underlie the development of acute myeloid leukemia, a deadly cancer of the blood and bone marrow.

2 May 2013

Tips for prevention and early detection of skin cancer

According to the American Cancer Society, an estimated 82,770 Americans will be diagnosed this year with skin cancer, including melanoma. When left untreated, melanoma is the most dangerous and aggressive form of skin cancer, accounting for more than 9,000 of the 12,000-plus skin cancer deaths each year.

2 May 2013

Researchers identify genetic mutation linked to a typical form of migraine

A research team led by a Howard Hughes Medical Institute investigator at the University of California, San Francisco has identified a genetic mutation that is strongly associated with a typical form of migraine.

2 May 2013

Details about genomic landscapes of AML and endometrial cancer revealed

Two studies from The Cancer Genome Atlas program reveal details about the genomic landscapes of acute myeloid leukemia and endometrial cancer.

2 May 2013

New hope for patients with myotonic dystrophy

There's hope for patients with myotonic dystrophy. A new small molecule developed by researchers at the University of Illinois has been shown to break up the protein-RNA clusters that cause the disease in living human cells, an important first step toward developing a pharmaceutical treatment for the as-yet untreatable disease.

2 May 2013

Gene study may uncover regulatory network that influences development of cardiovascular disease

University of North Carolina researchers have discovered that disrupting a gene that acts as a regulatory switch to turn on other genes can keep blood vessels from forming and developing properly.

30 Apr 2013

Analysis identifies 37 RNA molecules that might predict survival in breast cancer patients

A Big Data analysis that integrates three large sets of genomic data available through The Cancer Genome Atlas has identified 37 RNA molecules that might predict survival in patients with the most common form of breast cancer.

30 Apr 2013

Berkeley Lab researchers unveil analytical technique for easy comparisons of proteins in solution

A revolutionary X-ray analytical technique that enables researchers at a glance to identify structural similarities and differences between multiple proteins under a variety of conditions has been developed by researchers with the U.S. Department of Energy's Lawrence Berkeley National Laboratory.

30 Apr 2013

Researchers identify how a defective protein plays central role in Giant Axonal Neuropathy

A team of international researchers led by Northwestern Medicine scientists has identified how a defective protein plays a central role in a rare, lethal childhood disease known as Giant Axonal Neuropathy, or GAN.

29 Apr 2013

New treatment strategy for patients with CMT disease on the horizon

A potential new treatment strategy for patients with Charcot-Marie-Tooth disease is on the horizon, thanks to research by neuroscientists now at the University at Buffalo's Hunter James Kelly Research Institute and their colleagues in Italy and England.

29 Apr 2013

Evidence shows progerin induced by ultraviolet light is responsible for premature skin aging

A study conducted by researchers at Boston University School of Medicine (BUSM) provides new evidence that longwave ultraviolet light (UVA) induces a protein that could result in premature skin aging.

26 Apr 2013

Researchers discover gene that can cause 3 different diseases depending on its alteration

An international research consortium led by the Universitat Aut-noma de Barcelona (UAB), the CIBERER and the University of Wurzburg (Germany) has discovered a gene that can cause three totally different diseases, depending on how it is altered.

26 Apr 2013

Study reveals a new way for detecting colorectal cancers

A unique new study led by University of Kentucky Markey Cancer Center researchers Guo-Min Li and Libya Gu, in collaboration with Dr. Wei Yang at National Institutes of Health, reveals a novel mechanism explaining the previously unknown root cause of some forms of colorectal cancers.

26 Apr 2013

Multidrug-resistant tuberculosis (MDR-TB): an interview with Dr. Jennifer Cohn, Médecins Sans Frontières

MDR-TB is tuberculosis, a mycobacterial infection, that has developed resistance to two important and powerful first-line anti-TB drugs, INH and rifampin.

26 Apr 2013

To avoid difficulties experienced during SARS epidemic, China must remain transparent in H7N9 efforts

"On this 10th anniversary of China's April 2003 admission that the SARS virus had spread across that country ... Beijing finds itself once again in a terrible position via-a-vis the microbial and geopolitical worlds," Laurie Garrett, a senior fellow for global health at the Council on Foreign Relations, writes in a Foreign Policy opinion piece, noting the emergence of a new strain of bird flu, H7N9, in the country.

25 Apr 2013

Astrocytes more effective in promoting recovery after brain injury

The production of a certain kind of brain cell that had been considered an impediment to healing may actually be needed to staunch bleeding and promote repair after a stroke or head trauma, researchers at Duke Medicine report.

25 Apr 2013

Individuals with MEN1 are at increased risk of developing neuroendocrine tumors

A mutation in a protein called menin causes a hereditary cancer syndrome called MEN1 (multiple endocrine neoplasia type 1).

25 Apr 2013

Investigational treatment for ALS passes early phase clinical trial for safety

An investigational treatment for an inherited form of Lou Gehrig's disease has passed an early phase clinical trial for safety, researchers at Washington University School of Medicine in St. Louis and Massachusetts General Hospital report.

24 Apr 2013

PPMI to launch additional study to evaluate multiple potential biomarkers for Parkinson's disease

The Parkinson's Progression Markers Initiative, a landmark biomarker clinical study, has completed enrollment of its initial 600-member cohort of Parkinson's patients and controls, and will launch additional study cohorts to leverage the existing PPMI infrastructure and evaluate multiple potential biomarkers for Parkinson's disease.

24 Apr 2013

University of Leicester study investigates early detection of pancreatic cancer

Pioneering research to investigate whether pancreatic cancer can be detected early through a blood test is to be spearheaded by the University of Leicester thanks to new funding provided by Hope Against Cancer.

24 Apr 2013

Mutation News and Research

Findings set the stage for identifying potential new drug targets, treatment strategies for AML

Tips for prevention and early detection of skin cancer

Researchers identify genetic mutation linked to a typical form of migraine

Details about genomic landscapes of AML and endometrial cancer revealed

New hope for patients with myotonic dystrophy

Gene study may uncover regulatory network that influences development of cardiovascular disease

Analysis identifies 37 RNA molecules that might predict survival in breast cancer patients

Berkeley Lab researchers unveil analytical technique for easy comparisons of proteins in solution

Researchers identify how a defective protein plays central role in Giant Axonal Neuropathy

New treatment strategy for patients with CMT disease on the horizon

Evidence shows progerin induced by ultraviolet light is responsible for premature skin aging

Researchers discover gene that can cause 3 different diseases depending on its alteration

Study reveals a new way for detecting colorectal cancers

Multidrug-resistant tuberculosis (MDR-TB): an interview with Dr. Jennifer Cohn, Médecins Sans Frontières

To avoid difficulties experienced during SARS epidemic, China must remain transparent in H7N9 efforts

Astrocytes more effective in promoting recovery after brain injury

Individuals with MEN1 are at increased risk of developing neuroendocrine tumors

Investigational treatment for ALS passes early phase clinical trial for safety

PPMI to launch additional study to evaluate multiple potential biomarkers for Parkinson's disease

University of Leicester study investigates early detection of pancreatic cancer

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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