Protein C News and Research

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Study suggests the gut microbiota may be one of the factors determining the physiological inter-sex differences in pain perception

Researchers investigated whether the gut-brain axis could influence pain thresholds.

10 Jun 2022

Study investigates SARS-CoV-2 escape from nirmatrelvir

Researchers assessed SARS-CoV-2 Alpha, Delta, and Omicron variants’ resistance to nirmatrelvir, a protease inhibitor of SARS-CoV-2.

10 Jun 2022

Association of neuronal and non-neuronal GABA with neuropsychiatric illness in COVID-19 patients

A new study published in the journal Reports focused on the hijacking of the pancreatic, endothelial, and gut GABA by SARS-CoV-2 and its associated pathology along with interventions.

10 Jun 2022

Core body temperature increases host resistance to influenza virus and SARS-CoV-2 infection

A recent article posted to the Research Square* preprint server demonstrated that high body temperature elevates gut microbiota-reliant host resistance against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and influenza A viral infection.

10 Jun 2022

Study reports robust immunity to SARS-CoV-2 including Omicron BA.1 for all three primary vaccines

In a recent study posted to the medRxiv* pre-print server, researchers in the United Kingdom investigated the effect of two Pfizer/BioNTech BNT162b2 vaccine doses or Oxford/AstraZeneca AZ1222 coronavirus disease 2019 (COVID-19) vaccination and a subsequent BNT162b2 booster dose in a cohort of healthcare workers (HCWs) over six to nine months.

10 Jun 2022

Research reveals why many cancers are vulnerable to FDA-approved IDH1 inhibitors

A drug used to target IDH1 mutations in select cancers also appears to inhibit the wild-type form of the enzyme, under certain conditions.

9 Jun 2022

A comparison of SARS-CoV-2 and influenza cytokine storms

In a recent study published in the Journal of Interferon & Cytokine Research, researchers compared the cytokine storms of pandemic influenza and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections.

9 Jun 2022

Inhaled recombinant IL-15 tested in pet dogs with metastatic lung disease from osteosarcoma or melanoma

A protein that the body naturally produces could become an important new immunotherapy drug in the cache of cancer-fighting tools available to oncologists.

9 Jun 2022

Alternative remedy to conventional root canals would regenerate lost tooth pulp

Each year, dentists in the United States perform more than 15 million root canals on infected teeth, removing the inflamed pulp and filling the emptied canal with inert materials such as rubber and cement. What remains is a mineral shell in place of a living tooth.

9 Jun 2022

Cryo-EM helps scientists to decipher the structure of a key part of RNA degradation machinery

In biology, getting rid of stuff can be just as important as making it. A buildup of cells, proteins, or other molecules that are no longer needed can cause problems, so living things have evolved several ways to clean house.

9 Jun 2022

Targeting fatty acid metabolism holds promise for Parkinson's disease

The human brain is lipid rich. Lipids and fatty acids contribute to many important cellular processes. Alpha-synuclein - a protein that plays a critical role in Parkinson's disease (PD) - is known to interact with and alter the balance of lipids and fatty acids.

9 Jun 2022

Researchers reveal important factor behind cancer therapy resistance and a way to counter it

Why doesn't every cancer patient respond to immunotherapy? That's the question that researcher Daniel Peeper is looking to answer.

9 Jun 2022

Artificial intelligence-based computational program predicts the 3D structure of rotavirus spike protein

Of the three groups of rotavirus that cause gastroenteritis in people, called groups A, B and C, groups A and C affect mostly children and are the best characterized.

9 Jun 2022

Study shines new light on the role of key Parkinson’s disease protein

One of the hallmarks of Parkinson's disease (PD) is the accumulation in the brain of a protein known as alpha-synuclein. For more than two decades, alpha-synuclein has been a focal point of attention for researchers, clinicians and drug makers interested in PD.

9 Jun 2022

Researchers create first comprehensive functional map of genes expressed in human cells

Curia and Replicate Bioscience Enter Strategic Collaboration to Create Groundbreaking Development Platform for Self-Replicating RNA (srRNA)

From Curia 9 Jun 2022

The presence of residual SARS-CoV-2 antigens in post-convalescent tissues

Researchers investigated the residual SARS-CoV-2 antigen found in long COVID-19 patients.

9 Jun 2022

Insights on the T cell epitope landscape for the five main SARS-CoV-2 variants of concern

Researchers generated an AI resource to characterize the T cell epitope landscape for SARS-CoV-2 variants of concern.

9 Jun 2022

Protein C News and Research

Study suggests the gut microbiota may be one of the factors determining the physiological inter-sex differences in pain perception

Study investigates SARS-CoV-2 escape from nirmatrelvir

Association of neuronal and non-neuronal GABA with neuropsychiatric illness in COVID-19 patients

Core body temperature increases host resistance to influenza virus and SARS-CoV-2 infection

Study reports robust immunity to SARS-CoV-2 including Omicron BA.1 for all three primary vaccines

Research reveals why many cancers are vulnerable to FDA-approved IDH1 inhibitors

A comparison of SARS-CoV-2 and influenza cytokine storms

Inhaled recombinant IL-15 tested in pet dogs with metastatic lung disease from osteosarcoma or melanoma

Alternative remedy to conventional root canals would regenerate lost tooth pulp

Cryo-EM helps scientists to decipher the structure of a key part of RNA degradation machinery

Targeting fatty acid metabolism holds promise for Parkinson's disease

Researchers reveal important factor behind cancer therapy resistance and a way to counter it

Artificial intelligence-based computational program predicts the 3D structure of rotavirus spike protein

Study shines new light on the role of key Parkinson’s disease protein

Researchers create first comprehensive functional map of genes expressed in human cells

USA–Japan Workshop participants present cutting-edge research on biomarkers for early detection of cancer

New disease that affects the macula discovered

Curia and Replicate Bioscience Enter Strategic Collaboration to Create Groundbreaking Development Platform for Self-Replicating RNA (srRNA)

The presence of residual SARS-CoV-2 antigens in post-convalescent tissues

Insights on the T cell epitope landscape for the five main SARS-CoV-2 variants of concern

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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