Adenocarcinomas News and Research

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MGH researchers identify potential markers of lung cancer

By examining both blood samples and tumor tissues from patients with non-small-cell lung cancer, investigators at Massachusetts General Hospital have identified markers that can distinguish between major subtypes of lung cancer and can accurately identify lung cancer stage.

16 Jul 2019

Early genome catastrophes can lead to development of lung cancer in non-smokers

Catastrophic rearrangements in the genome occurring as early as childhood and adolescence can lead to the development of lung cancer in later years in non-smokers.

31 May 2019

Cervical cancer subtype increasing in several subpopulations of women

A new study reports that a type of cervical cancer that is less amenable to Pap testing is increasing in several subpopulations of women, pointing to the growing importance of human papillomavirus (HPV) testing and vaccination.

17 Apr 2019

New analysis highlights increasing focus of early-stage clinical trials on rare cancers

The proportion of early-stage drug trials tackling the biggest cancer killers has declined sharply since the early 1990s as less common tumor types receive increasing attention, according to new research to be presented during the International Congress on Targeted Anticancer Therapies 2019, taking place from today to 27 February in Paris, France.

25 Feb 2019

New study finds how high-fat diets fuel colorectal cancer growth

As cancer death rates drop overall, doctors have noted a frightening anomaly: deaths from colorectal cancer in people under 55 appear to be creeping up. According to the American Cancer Society, deaths in this younger group increased by 1 percent between 2007 and 2016.

22 Feb 2019

New test shown to be 100% effective at detecting cervical cancer

Researchers have developed a new cervical cancer test that proved to be 100% effective at detecting the cancer in a trial of 15,744 participants.

19 Dec 2018

New 'epigenetics-based' cervical cancer test outperforms Pap smear and HPV tests

A new test for cervical cancer was found to detect all of the cancers in a randomized clinical screening trial of 15,744 women, outperforming both the current Pap smear and human papillomavirus test at a reduced cost, according to a study led by Queen Mary University of London.

17 Dec 2018

Screening for HPV could replace routine Pap smears

According to health advisors from the U.S. Preventive Services Task Force, Pap smears may not be the only way to check for cervical cancer risk among women.

22 Aug 2018

ETH scientists discover new cancer-specific molecular changes in tumor tissues

A research team led by Gunnar Raetsch, Professor of Biomedical Informatics at ETH Zurich, has evaluated the largest set of genetic data in cancer medicine: The Cancer Genome Atlas in the United States.

9 Aug 2018

Study identifies distinct genetic mutations in appendix cancer that may impact treatment

The rarity of appendix cancer, accounting for less than 1 percent of tumors that originate in the gastrointestinal tract, and the lack of scientific data for this disease means that current treatment guidelines recommend applying therapies to people with appendix cancer that are intended for those with colon cancer.

9 Aug 2018

Conservative management of lung subsolid nodules reduces overtreatment and unnecessary surgery

Subsolid nodules can be considered a biomarker of lung cancer risk and should be managed with long-term active surveillance.

18 Jul 2018

Deadlier subtype of metastatic prostate cancer found to be common than previously thought

A new study of prostate cancer in 202 men, whose cancers had spread and were resistant to standard treatment, found that a surprisingly large number of these cancers – about 17 percent – belong to a deadlier subtype of metastatic prostate cancer.

12 Jul 2018

Researchers find new marker for better prognosis in gastric and esophageal cancer

Tumors that develop at the transition of the stomach to the esophagus, so-called adenocarcinomas of the gastroesophageal transition, are still difficult to treat and the chances of recovery are still low.

2 Jul 2018

Pancreatic cancer patients with BRCA1 or BRCA2 mutations fare better on platinum-based chemotherapy

A small study of adults with the most common form of pancreatic cancer adds to evidence that patients with BRCA1 or BRCA2 gene mutations long linked to a high risk of breast cancer have poorer overall survival rates than those without the mutations.

17 May 2018

Modifying Oncolytic Adenoviruses to Target Pancreatic Cancer

Pancreatic cancer is one of the less common but deadliest cancers. Modified oncolytic adenoviruses represent an alternative to chemotherapy and targeted therapies, which have a high mortality rate.

9 Mar 2018

Cancer researchers make breakthrough in identifying genetic changes during immunotherapy

For some cancer patients, the road to remission and healing can have its share of speed bumps. That's particularly true of patients with non-small cell lung cancer (NSCLC) who develop a secondary, or acquired, resistance to immunotherapy, which initially was effective against their tumors.

28 Oct 2017

RUDN University scientists synthesize new range of cytotoxic substances

Scientists from RUDN University have synthesized a number of new cytotoxic substances - the ones that can damage cells. In the future the results of the study can be used in cancer therapy.

13 Oct 2017

Scientists discover novel therapeutic strategy to treat aggressive subgroup of lung cancer

Research conducted by a team of Norton Thoracic Institute scientists on a novel therapeutic avenue for an aggressive and difficult to treat subgroup of lung cancer was published in the August 15, 2017 issue of Cancer Research.

17 Aug 2017

Colorectal cancer deaths on the rise among Americans: JAMA study

A new study from the American Cancer Society has found that more people living in the United States of America are dying from colon and rectal cancers around the age of 50 years when they are supposed to officially begin screening for these cancers. The new study is published in the JAMA, the Journal of the American Medical Association.

10 Aug 2017

Kinase-inactive BRAF mutation triggers lung adenocarcinoma development

The initiating oncogenic event in almost half of human lung adenocarcinomas is still unknown, a fact that complicates the development of selective targeted therapies.

2 Aug 2017