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Study: Early advanced therapy significantly improves Crohn's disease outcomes

A large-scale clinical trial of treatment strategies for Crohn's disease has shown that offering early advanced therapy to all patients straight after diagnosis can drastically improve outcomes, including by reducing the number of people requiring urgent abdominal surgery for treatment of their disease by ten-fold.

22 Feb 2024

Canagliflozin reduces atherosclerosis and modulates inflammatory, oxidative pathways in mice

Announcing a new article publication for Cardiovascular Innovations and Applications journal. This study was aimed at investigating the effect of canagliflozin (Cana) on atherosclerosis and further exploring its potential mechanism. ApoE−/− mice were fed a Western diet (WD) and randomly divided into a WD group and WD+Cana group.

19 Feb 2024

Mussel oil beats fish oil in atherosclerosis prevention, animal study finds

A study in "Frontiers in Nutrition" shows mussel oil significantly outperforms fish oil in preventing atherosclerosis in mice, suggesting a potential superior dietary supplement for human cardiovascular health.

14 Feb 2024

Extract from pomegranate peels and seeds shows anti-hypertensive properties

The efficacy of an extract obtained from the non-edible parts of pomegranates.

14 Feb 2024

Double whammy: Stroke and neck artery tear increase heart attack risk in the first year

Heart attack risk almost doubles in the first year after a stroke or when combined with a tear in a neck artery wall, however, a tear without a stroke does not seem to raise heart attack risk, according to preliminary research to be presented at the American Stroke Association's International Stroke Conference 2024.

1 Feb 2024

Angelica gigas extract emerges as a potential treatment for vascular disease

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 23, entitled, "Angelica gigas extract inhibits acetylation of eNOS via IRE1α sulfonation/RIDD-SIRT1-mediated posttranslational modification in vascular dysfunction."

28 Dec 2023

Smidt Heart Institute at Cedars-Sinai opens Aortic Surveillance Clinic for patients with enlarged aortas

The Smidt Heart Institute at Cedars-Sinai has opened an Aortic Surveillance Clinic for the evaluation and long-term monitoring of patients with enlarged aortas, or aortic aneurysms, for whom surgery may not be necessary.

26 Dec 2023

Embryonic immune sensor could key to creating patient-derived blood stem cells

A microbial sensor that helps identify and fight bacterial infections also plays a key role in the development of blood stem cells, valuable new insight in the effort to create patient-derived blood stem cells that could eliminate the need for bone marrow transplants.

19 Dec 2023

Physics-based metric predicts aortic aneurysm growth with 98% accuracy

Northwestern University researchers have developed the first physics-based metric to predict whether or not a person might someday suffer an aortic aneurysm, a deadly condition that often causes no symptoms until it ruptures.

15 Dec 2023

New genetic links to coronary artery calcification uncovered, offering treatment insights

A study in Nature Cardiovascular Research identifies two new genetic loci associated with coronary artery calcification (CAC), a key indicator of atherosclerosis and coronary artery disease.

5 Dec 2023

Scientists uncover cellular cause of heart defects in babies born to women with diabetes

When women with diabetes become pregnant, they face not only the typical challenges of pregnancy and impending parenthood, but also a scary statistic: they're five times more likely to have a baby with a congenital heart defect.

30 Nov 2023

Young people may be more susceptible to the effects of elevated blood cholesterol and hypertension

Young people may be more susceptible to the effects of the risk factors for developing atherosclerosis. According to a study carried out at the Centro Nacional de Investigaciones Cardiovasculares (CNIC), younger people are especially vulnerable to the damaging effects of elevated blood cholesterol and hypertension, two of the major modifiable cardiovascular risk factors.

20 Nov 2023

Scientists achieve breakthrough in treating 'neglected' polymyalgia rheumatica

Scientists have found success in treating a 'neglected' inflammatory condition, polymyalgia rheumatica, with a drug that could provide an alternative to steroids for patients.

25 Oct 2023

New technique to control severe bleeding increases risk of death, study finds

A new technique used to control severe bleeding in injured patients has been found to increase the risk of death, according to new research from the University of Aberdeen, in Scotland, which was led by University of Alabama at Birmingham trauma surgeon and professor Jan Jansen, Ph.D. Jansen was a surgeon and researcher in Aberdeen before moving to the United States in 2017.

13 Oct 2023

New study reveals inequalities in the provision of heart valve replacement surgery

There are striking inequalities in the provision of major (aortic) heart valve replacement surgery across England, with women, Black and Asian people, and those living in areas of deprivation much less likely to receive the life-saving procedure, suggests a large data analysis, published in the open access journal Open Heart.

4 Oct 2023

Rasip1 gene found to be intimately involved in the creation of blood cells

Blood has long been a symbol of life and health, so it may be surprising that some aspects of blood production, i.e., hematopoiesis, remain incompletely understood.

13 Sep 2023

University of Kentucky's cardiovascular scientist recognized for excellence in hypertension research

The University of Kentucky's Vice President for Research and leading cardiovascular scientist is being recognized for her foundational work in the field of hypertension with a prestigious award from the American Heart Association (AHA).

12 Sep 2023

CPAP use reduces risk of death from cardiovascular disease in sleep apnea patients

People suffering with obstructive sleep apnoea (OSA) can reduce their risk of dying from cardiovascular disease if they use a continuous positive airway pressure (CPAP) machine at night, according to research presented at the European Respiratory Society International Congress in Milan, Italy.

11 Sep 2023

The effect of coffee consumption on abdominal aortic calcification among adults

How coffee consumption affects the incidence of abdominal aortic calcification.

23 Jun 2023

New ultra-high-resolution CT enables accurate diagnosis of coronary artery disease in high-risk patients

New ultra-high-resolution CT technology enables excellent image quality and accurate diagnosis of coronary artery disease in high-risk patients, a potentially significant benefit for people previously ineligible for noninvasive screening, according to a study published in Radiology, a journal of the Radiological Society of North America (RSNA).

20 Jun 2023