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New study shows how brain glucose affects fungal disease treatment

Metabolite-drug-fungal interactions in the fungal meningitis pathogen Cryptococcus neoformans.

16 Jan 2024

Drug-resistant Candida: Study uncovers evolutionary tricks of a fungal pathogen

Global fungal infections, which affect one billion people and cause 1.5 million deaths each year, are on the rise due to the increasing number of medical treatments that heighten vulnerability.

12 Jan 2024

Study finds Epstein-Barr virus T-cells prevalent in early multiple sclerosis

A study led by UTHealth Houston reveals that T-cells specific for Epstein-Barr virus-infected cells are highly present in the cerebrospinal fluid of people with early-stage multiple sclerosis, suggesting a link between EBV and the disease.

8 Jan 2024

New research may pave the way for treatment of vaginal yeast infections

New research could one day pave the way for the treatment of vaginal yeast infections, by shedding new light on how microbes in the body absorb zinc.

6 Dec 2023

Green tea-silver nanoparticles: A promising weapon against superbugs

Once upon a time, people believed to be invincible against bacterial diseases, thanks to the antibiotics. Does this sound like a fairy tale? By all means! Nothing could be further from the truth.

17 Nov 2023

Scientists discover kidney-friendly antifungal that evades resistance

In this investigation, researchers produced powerful antifungals of the polyene class without nephrotoxicity.

9 Nov 2023

Study sheds light on role of gut fungi in severe COVID-19 and long COVID

Certain gut-dwelling fungi flourish in severe cases of COVID-19, amplifying the excessive inflammation that drives this disease while also causing long-lasting changes in the immune system, according to a new study led by investigators at Weill Cornell Medicine and NewYork-Presbyterian.

24 Oct 2023

Study shows widespread prevalence of dangerous pathogens in ventilated patients

University of Maryland School of Medicine (UMSOM) researchers conducted a statewide survey of all patients on breathing machines in hospitals and long-term care facilities and found that a significant percentage of them harbored two pathogens known to be life-threatening in those with compromised immune systems.

15 Oct 2023

Study identifies significant percentage of ventilated patients colonized with life-threatening pathogens

13 Oct 2023

New insights into how neutrophils fight Candida albicans infection

Umeå University researchers, Sweden, unveil how the most common white blood cells, neutrophils, counter Candida albicans toxin stopping its tracks.

5 Oct 2023

Yeast in the gut linked to Crohn's disease inflammation, opening new doors for treatment

New study in Nature Medicine links yeast cells in the gastrointestinal tract to abnormal immune responses causing inflammation in Crohn's disease patients. The research suggests that these yeast-reactive T-cells could be a potential therapeutic target, offering new avenues for treatment.

27 Sep 2023

Gut feeling: How your microbiome could be shaping your mental health

Researchers in Biological Psychiatry delve into the complex relationship between the gut microbiome and mental health disorders like depression and bipolar disorder. The study explores how not just gut bacteria, but also lesser-known gut microorganisms such as viruses, fungi, and parasites, play a pivotal role in mood disorders.

5 Sep 2023

Glycans and GBPs: How their interplay shapes immunity in infection and autoimmune diseases

Researchers discuss the regulatory roles of glycans and glycan-binding proteins in modulating immune responses.

21 Aug 2023

Maintaining the health of the gut microbiome by a new peptide

Peptide YY (PYY), a hormone produced by gut endocrine cells that was already known to control appetite, also plays an important role in maintaining the balance of fungi in the digestive system of mammals, according to new research from the University of Chicago.

4 Aug 2023

New way to attack fungal infections discovered

Researchers at the RIKEN Center for Sustainable Research Science (CSRS) and the University of Toronto have discovered a new way to attack fungal infections.

31 Jul 2023

NIAID awards $13.7 million grant to investigate multidrug resistant organisms in nursing homes

The National Institute of Allergy and Infectious Diseases (NIAID) has awarded a $13.7 million, five-year grant to a team of researchers to investigate multidrug resistant organisms (MDROs) in nursing homes throughout the United States.

25 Jul 2023

Study offers a comprehensive analysis of bacterial and fungal alterations in COVID-19

Researchers use nanopore sequencing to determine the fungal and bacterial microbiota in the lungs of COVID-19 and non-COVID-19 patients.

24 Jul 2023

Understanding the mechanisms behind rising antifungal drug resistance

In a recent study, researchers addressed the issue of the rise of antifungal drugs-resistant infections and the advent of multidrug-resistant fungal pathogens.

19 Jul 2023

AI and infection control: preventing infectious disease outbreaks and pandemics

Researchers discussed the role of artificial intelligence (AI) in preventing outbreaks of infectious diseases and future pandemics.

19 Jul 2023

PALACE study: Direct oral challenge can safely remove penicillin allergy label

Penicillin allergy affects more than 25 million people in the United States (up to 1 in 10 Americans) and has been shown to lead to particularly poor health outcomes in pregnant women and surgical patients. It is also a public health threat, leading to antibiotic resistance and infections in hospitalized patients that can be life threatening.

17 Jul 2023