Chronic Pain News and Research

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New brain circuit discovery offers hope for chronic pain treatment

A new map of a brain circuit specific to chronic pain suggests a promising route to treatment for the roughly 60 million Americans living with persistent pain, according to a study published in Nature.

1 Apr 2026

Highly potent opioid shows potential as therapy for pain and opioid use disorder

Researchers at the National Institutes of Health (NIH) have identified a novel, highly potent opioid that shows potential as a therapy for both pain and opioid use disorder.

1 Apr 2026

Treating autonomic dysfunction can relieve symptoms of treatment-resistant depression

Consider a house with the water main half shut. The faucets sputter. The toilet runs all night. The garden wilts. You could call a plumber for the faucet, a landscaper for the garden, a different plumber for the toilet, and every one of them would fix something while fixing nothing.

31 Mar 2026

Artemin identified as marker and target in feline osteoarthritis

By comparing osteoarthritis pain pathways known to be active in dogs and humans to those in cats with degenerative joint disease (DJD), researchers found that elevation of a particular molecule, artemin, could serve as a marker of disease (and possibly pain) as well as a potential therapeutic target.

30 Mar 2026

TENS therapy reduces movement pain and fatigue in fibromyalgia patients

Adding TENS (transcutaneous electrical nerve stimulation) to outpatient physical therapy reduced movement-based pain and fatigue in patients with fibromyalgia, and the effects lasted for at least six months, according to a new study led by researchers at University of Iowa Health Care.

27 Mar 2026

Breast reduction surgery is linked to lower diabetes and heart risk

Findings suggest breast reduction surgery is associated with lower long-term diabetes and cardiovascular risks, enhancing women's metabolic health.

24 Mar 2026

Chronotherapy offers new hope for timing pain relief to match body cycles

Time plays a key role in our perception of pain and administering pain relief and medication for chronic pain-related depression may be more effective at certain times of day, UCL and University of Toronto researchers say.

23 Mar 2026

Precise application of radio waves could help counter neurological conditions

A new study found that precise application of radio waves can change the activity of brain cells in ways that could counter neurological conditions.

18 Mar 2026

Using machine learning to identify individuals at risk for intimate partner violence

Researchers at Mass General Brigham have developed a series of artificial intelligence (AI) tools that uses machine learning to identify individuals who may be at risk for intimate partner violence (IPV) using information from their electronic medical records (EMRs).

13 Mar 2026

Cellular roadmap offers new targets for improving rotator cuff surgical repair

Rotator cuff tears are among the most common and debilitating musculoskeletal injuries, frequently causing chronic pain, reduced shoulder mobility, and a high risk of re-injury even after surgical repair.

9 Mar 2026

Georgia Tech receives major funding to develop lymphatic disease therapy

The Georgia Institute of Technology has been awarded up to $21.8 million from the Advanced Research Projects Agency for Health (ARPA-H) to deliver a first-of-its-kind therapy to patients with lymphatic disease.

4 Mar 2026

UCF researcher explores insulin signaling as new target for diabetic neuropathy

Neuropathy – chronic pain, numbness and tingling in the hands and feet – is a challenging fact of life for many patients with Type 1 diabetes.

2 Mar 2026

Chronic back pain linked to heightened sound sensitivity in the brain

People with chronic back pain process everyday sounds differently, and more intensely, than people without pain, according to new research from the University of Colorado Anschutz.

2 Mar 2026

NIH’s continued investment fuels TMJ pain research

Chronic pain is one of the most common health conditions worldwide. Back pain is the most frequently reported type, followed closely by head and face pain linked to the jaw joint, in the form of temporomandibular joint (TMJ) disorder.

27 Feb 2026

Five sessions a day TMS approach may reduce depression symptoms in one week

For the many patients with depression who haven't found relief through medication, transcranial magnetic stimulation (TMS) - a noninvasive therapy that uses magnetic pulses to stimulate specific areas of the brain - has become an increasingly important treatment option.

23 Feb 2026