Fatigue News and Research

RSS

Study reveals impaired glymphatic function in people living with ME/CFS

The brain's waste clearance system is impaired in people living with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) which can lead to various symptoms including brain fog, Griffith University researchers have discovered.

2 Jul 2026

Ten weeks of cognitive rehabilitation reverses long Covid brain fog

Ten weeks of cognitive rehabilitation can help people with long Covid symptoms such as brain fog achieve their goals in returning to work and hobbies, finds a new clinical trial led by University College London (UCL) researchers.

1 Jul 2026

Review highlights strong safety and effectiveness of mRNA vaccines

A comprehensive new review published in The Lancet affirms that currently approved mRNA vaccines are safe and highly effective at preventing infectious diseases, including COVID-19.

30 Jun 2026

New anti-lipid antibodies could improve diagnosis of Lyme disease

Lyme disease can be easiest to treat in its earliest stages, but current tests often miss infections during that critical window and cannot tell whether bacteria are still present or were cleared years ago.

30 Jun 2026

Eye-tracking technology reveals design flaws in intravenous smart pumps

Researchers at the University of Massachusetts Amherst are using eye-tracking technology to help understand how nurses interact with intravenous smart pumps, providing a new way to identify design flaws in systems associated with more medication errors than any other route of administration.

29 Jun 2026

Unexplained skin darkening leads to life-saving Addison's disease diagnosis

A 24-year-old woman presented with two years of unexplained darkening of her hands, feet, gums, and tongue.

26 Jun 2026

Recognizing perinatal heart failure early reduces life-threatening risks

Early detection and timely treatment of heart failure in pregnant or postpartum women are crucial to prevent serious complications, such as irregular heartbeat, stroke and death, according to a new American Heart Association scientific statement, "Heart Failure Occurring in the Perinatal Period."

25 Jun 2026

Hourly movement breaks effectively counter harms of prolonged sitting

Hourly movement breaks of just 5 minutes each seem to offer the best balance between feasibility and effectiveness for mitigating the health harms of prolonged sitting, suggests a large study carried out under real world conditions and published online in the British Journal of Sports Medicine.

24 Jun 2026

A night without sleep alters neural connections in human brains

A night without sleep produced increased markers of connections between brain cells, showing that sleep in humans may be important for restoring cellular balance in the brain, according to a study published June 23rd in the open access journal PLOS Biology by David Elmenhorst from the Forschungszentrum Jülich Institute of Neuroscience and Medicine in North Rhine-Westphalia, Germany, and colleagues.

23 Jun 2026

Trial identifies 4 grams a day as the tested safe level for L-tyrosine in healthy men

A randomized, crossover trial in healthy adult men found that 4 weeks of L-tyrosine supplementation at doses up to 4 g/day did not cause clinically meaningful changes in safety markers, diet, blood pressure, or body measures. The highest tested dose, 4 g/day, was identified as the no-observed-adverse-effect level under the study’s four-week conditions, although broader and longer-term studies are still needed.

23 Jun 2026

Study links neuroimmune dysregulation to complex fibromyalgia symptoms

Fibromyalgia is a complex disorder characterized primarily by chronic widespread pain, fatigue and other physical and cognitive symptoms.

22 Jun 2026

How clinicians can identify and manage Ebola, hantavirus

Two deadly infectious diseases, Ebola https://www.cmaj.ca/lookup/doi/10.1503/cmaj.260834 and hantavirus https://www.cmaj.ca/lookup/doi/10.1503/cmaj.260789, have made headlines in recent weeks as they pose serious threats to public health.

22 Jun 2026

Milken Institute and Ann Theodore Foundation fund early-career sarcoidosis research grants

The Milken Institute Science Philanthropy Accelerator for Research and Collaboration (SPARC), in partnership with the Ann Theodore Foundation (ATF), today announced that the Ann Theodore Foundation Learning Opportunities in Medicine and Sarcoidosis (ATF-LOMAS) grant program has committed its first cycle of funding, totaling US$600,000 to early-career faculty conducting biomedical research in sarcoidosis.

19 Jun 2026

Robotic exoskeleton system virtually connects stroke patients and therapists

Physical therapists have long walked alongside stroke survivors during recovery. Now, they are walking with them.

18 Jun 2026

JMIR articles address AI clinical decision-making and health care worker burnout

JMIR Publications released two feature stories in its News and Perspectives section. Shalini Kathuria Narang's "Can Humanlike Reasoning Be Replicated in Large Language Models for Clinical Decision-Making?" and Sara Novak's "How Health Care Workers Can Manage Digital Fatigue" offer complementary looks into the capabilities of artificial intelligence in diagnostics, and the real-world exhaustion faced by medical professionals managing digital systems.

16 Jun 2026

Tirzepatide outperforms semaglutide for real-world weight loss

Glucagon-like peptide-1 receptor agonists (GLP-1RAs) have become massively popular for weight loss, but results vary from person to person and drug to drug.

16 Jun 2026

Gut bacteria may help explain why fatigue appears before illness

A small study of healthy Japanese adults found that fatigue was associated with distinct gut microbiome, microbial gene, and fecal metabolite patterns. The findings suggest fatigue may track with altered microbial energy metabolism and oxidative stress-related functional potential, but larger longitudinal studies are needed to test causality and clinical value.

16 Jun 2026

Study identifies genetic marker associated with severe IBD

In the largest genetic study of inflammatory bowel disease (IBD) traits to date, researchers have identified a genetic marker that is associated with more severe ulcerative colitis and Crohn's disease – the major forms of IBD.

15 Jun 2026

Targeted reminders increase serious illness conversations in cancer care

New research in the June 2026 issue of JNCCN-Journal of the National Comprehensive Cancer Network finds that small, targeted prompts delivered to both patients and providers at the right moment can significantly increase the number of serious illness conversations that take place.

15 Jun 2026

Phase 3 study of in vivo CRISPR therapy for hereditary angioedema successfully completed

Researchers from Amsterdam UMC, in collaboration with other hospitals, have successfully completed the first-ever Phase 3 study of an in vivo CRISPR therapy.

13 Jun 2026