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Study shows gradual waning of MMR vaccine effectiveness over time

The MMR vaccine remains the best protection against measles, according to a modelling study in England which suggests the level of protection decreases slightly over time.

27 Sep 2024

Study: MMR vaccine remains the most effective measure to prevent measles infection

Most measles cases in England are among unvaccinated individuals. But, between 2011 and 2019, the proportion of measles cases in adults who received two doses of the MMR vaccine in England increased from 1.9% (20/1064) to 7.2% (57/790), however the cause of this increase remains unclear.

26 Sep 2024

COVID-19's impact on maternal mortality demands rethink of public health strategies

During the peak of the SARS-CoV-2 pandemic, there was an increase in maternal mortality in Chile. This is confirmed by a natural population experiment based on data from the Department of Health Statistics and Information (DEIS) of the Chilean Ministry of Health. The research was published in PLOS Global Public Health.

23 Jul 2024

One-time prime editing targets common genetic cause of cystic fibrosis

Researchers optimized prime editing for the efficient correction of the cystic fibrosis transmembrane conductance regulator F508del mutation in human airway epithelial cells, achieving high correction efficiencies and functional restoration with minimal off-target effects.

15 Jul 2024

4 ways vaccine skeptics mislead you on measles and more

Measles is on the rise in the United States. So far this year, the number of cases is about 17 times what it was, on average, during the same period in each of the four years before, according to the Centers for Disease Control and Prevention.

22 May 2024

Measles vaccine more likely to be completely ineffective in children born by C-section

A study by the University of Cambridge, UK, and Fudan University, China, has found that a single dose of the measles jab is up to 2.6 times more likely to be completely ineffective in children born by C-section, compared to those born naturally.

13 May 2024

Expanding treatment horizons for hypermutated urothelial carcinomas beyond immunotherapy

A new editorial paper was published in Oncoscience (Volume 11) on April 25, 2024, entitled, "Therapeutic opportunities for hypermutated urothelial carcinomas beyond immunotherapy."

10 May 2024

Understanding measles and the role of vaccination

With measles cases rising in Canada and internationally, it is important for clinicians to understand the disease and the role of vaccination against measles.

22 Apr 2024

CDC report: Persistent measles importations challenge U.S. elimination efforts

The status of measles elimination in the United States (U.S.).

16 Apr 2024

MMR vaccine slashes antibiotic use in toddlers: Nordic study shines light on broader benefits

Study demonstrates that administering the MMR vaccine to children under two, following three DTaP doses, significantly reduces the need for antibiotic treatments, highlighting potential non-specific protective effects.

26 Mar 2024

Measles outbreak in Illinois underscores critical need for vaccination

Study reports a measles outbreak among five unvaccinated children in Illinois, highlighting the disease's high transmissibility even among those not in direct contact, underscoring the critical importance of vaccination.

17 Mar 2024

Empathetic correction of misinformation can improve attitudes towards vaccination, study shows

An international study has shown for the first time how empathetic correction of misinformation among vaccine-hesitant patients can significantly improve attitudes towards vaccination – and potentially boost vaccine uptake.

4 Mar 2024

LTBR identified as potential target for cancer immunotherapy and marker of poor prognosis

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 1, entitled, "Systematic analysis of the prognostic value and immunological function of LTBR in human cancer."

23 Jan 2024

Breakthrough in gene editing: Enhanced virus-like particles promise new era in genetic disease treatment

Researchers developed an advanced prime editor-engineered virus-like particle (PE-eVLP) system, significantly enhancing gene editing efficiency in human cells and showing potential for treating genetic diseases.

9 Jan 2024

New study expands immunotherapy eligibility for colorectal and endometrial cancer patients

A new study shows thousands more patients diagnosed with colorectal and endometrial cancers could benefit from immunotherapy than are currently offered it.

29 Dec 2023

American Psychological Association report highlights effective strategies to combat misinformation

A recent report from the American Psychological Association reviewed the available psychological science research to explore and combat health misinformation.

4 Dec 2023

Researchers introduce CRISPR-mediated genome and cancer shredding as a conceptual paradigm to treat recurrent gliomas

Researchers demonstrated clustered regularly interspersed short palindromic repeats (CRISPR)-mediated elimination of glioblastoma (GBM) cells.

29 Nov 2023

Live vaccinations found to be safe for pediatric organ transplant recipients

Live vaccinations provided to children who previously received liver or kidney transplants were found to be safe and prompted an immune response to guard against several life-threatening conditions, according to a new study published Oct. 12, 2023, in JAMA Network Open.

16 Oct 2023

Next-gen intranasal vaccine takes on measles, mumps, and multiple COVID-19 variants in one shot

Researchers developed an intranasal trivalent measles-mumps-SARS-CoV-2 vaccine that provides robust protection against multiple coronavirus variants. Leveraging the established measles-mumps-rubella platform, this vaccine demonstrates broad and adaptable immune responses, especially against Delta and Omicron variants.

8 Oct 2023

Exercise boosts immune defense in Lynch syndrome patients

Aerobic exercise, specifically cycling, shows promise in reducing inflammation and boosting immune responses in the colonic tissue of Lynch syndrome patients, a group at high risk for colorectal cancer. The study suggests that regular exercise may offer a preventive approach for this patient population, though further randomized trials are needed.

24 Sep 2023