Psychosis News and Research

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Psychosis means abnormal condition of the mind, and is a generic psychiatric term for a mental state often described as involving a "loss of contact with reality". People suffering from psychosis are said to be ''psychotic.''

Genetic variations in Prader-Willi syndrome offer key insights into autism and psychosis

In a comprehensive Genomic Press Invited Expert Review, researchers from the University of Haifa have synthesized cutting-edge findings on Prader-Willi syndrome (PWS), revealing how this complex neurodevelopmental disorder serves as a critical model for understanding the interplay between autism spectrum disorder (ASD) and psychotic spectrum disorders (PSD).

20 May 2025

Medicaid payments barely keep hospital mental health units afloat. Federal cuts could sink them.

This town's hospital is a holdout on behalf of people going through mental health crises. The facility's leaders have pledged not to shutter their inpatient psychiatric unit, as dozens of other U.S. hospitals have.

12 May 2025

Adolescents with mental health conditions show different social media habits

Young people with a diagnosable mental health condition report differences in their experiences of social media compared to those without a condition, including greater dissatisfaction with online friend counts and more time spent on social media sites.

6 May 2025

Discovery sheds light on protein's role in myelin formation and schizophrenia

Research published in the Journal of Neurochemistry has detailed the role of a protein, hnRNP A1, in the formation and stability of myelin, suggesting an important impact on neurodegenerative diseases and mental disorders such as multiple sclerosis and schizophrenia.

17 Apr 2025

UQ's new research center aims to improve lives of people living with pain

One of the world's foremost pain experts has highlighted the risks of bypassing established processes for assessing the safety and effectiveness of medicines at the launch of a research center at the University of Queensland.

10 Apr 2025

Cannabis users have elevated dopamine levels associated with psychosis

A McGill University-led study found that people with cannabis use disorder (CUD) had elevated dopamine levels in a brain region associated with psychosis.

9 Apr 2025

Genetic breakthrough in psychiatry using long-read genomic sequencing

In a manuscript published today in the American Journal of Psychiatry titled Long-Read Genome Sequencing in Clinical Psychiatry: RFX3 Haploinsufficiency in a Hospitalized Adolescent With Autism, Intellectual Disability, and Behavioral Decompensation, authors describe how they leveraged long-read genomic sequencing (LRS) to make a genetic diagnosis in a17-year-old male with autism spectrum disorder, intellectual disability, and acute behavioral decompensation that would not have been possible by standard methods.

9 Apr 2025

How much will that surgery cost? 🤷 Hospital prices remain largely unhelpful.

It's a holy grail of health care: forcing the industry to reveal prices negotiated between health plans and hospitals — information that had long been treated as a trade secret.

2 Apr 2025

Scientists find links between bipolar disorder and rare loss-of-function variants in two genes

Scientists at deCODE genetics, a subsidiary of Amgen, reveal today in Nature Genetics associations between bipolar disorder and rare loss-of-function variants in two genes.

25 Mar 2025

Study links kynurenine pathway to adolescent depression

Depression is a mental health condition that affects 280 million people worldwide. It is twice as common in women than men and this pattern starts to develop during adolescence.

25 Mar 2025

Could a keto diet replace diabetes meds? New research explores the possibilities

A review published in Nutrients finds that ketogenic diets (KD) may offer superior benefits for weight loss, blood sugar control, and inflammation compared to other diets. Researchers also highlight potential mental health improvements but call for more clinical trials.

11 Mar 2025

Chronic cocaine use increases impulsivity

Findings indicate chronic cocaine use alters brain circuits, increasing impulsivity in low-impulsive rats, contradicting previous assumptions about addiction.

5 Mar 2025

Understanding sex differences in the genetic basis of schizophrenia

A joint research study conducted by the UAB and the UB has analyzed the relation between the genetic risk of having schizophrenia and mild subclinical traits in people of the general population.

26 Feb 2025

"Normal" vitamin B12 levels may not prevent brain decline

Researchers identify associations between B12 levels currently accepted as normal and markers of neurological injury or impairment.

24 Feb 2025

Genetic mutation linked to schizophrenia in both humans and mice

A genetic mutation found in two human patients with schizophrenia also increased schizophrenia-related behaviors in mice with the same mutation, a rare finding of a direct genetic link to psychosis, report researchers at the University of Illinois Urbana-Champaign and colleagues in Massachusetts and Germany.

19 Feb 2025

Researchers uncover the brain mechanism behind ketamine's action

Ketamine has received a Hollywood makeover. It used to be known as a rave drug (street name special K) and cat anesthetic.

14 Feb 2025

Identifying key brain circuit opens doors for new psychosis treatments

Our study investigated the brain circuits involved in psychosis-a condition characterized by delusions, hallucinations, disorganized thinking and detachment from reality.

13 Feb 2025

UCLA Health launches study on ketogenic diet for bipolar disorder in youth

UCLA Health is set to begin a multi-site pilot study to explore whether a ketogenic diet, when combined with mood stabilizing medications, helps stabilize mood symptoms in teenagers and young adults who have bipolar disorder.

8 Feb 2025

Rising cannabis use disorder cases contribute to growing schizophrenia diagnoses

The proportion of new cases of schizophrenia associated with a cannabis use disorder has risen from 4% pre-legalization to 10% after cannabis legalization in Ontario, according to new research.

5 Feb 2025

Study aims to explore structural alterations in the brains of people with bipolar disorder

A new study, led by USC Mark and Mary Stevens Neuroimaging and Informatics Institute (Stevens INI), will explore structural alterations in the brains of people with bipolar disorder (BD), a chronic mental illness with one of the highest rates of attempted suicide - and for which no biological tools currently exist to guide diagnosis or treatment.

29 Jan 2025