Bone Marrow News and Research

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Bone Marrow is the soft, sponge-like tissue in the center of most bones. It produces white blood cells, red blood cells, and platelets.

Study: Most pediatric cancer patients have mild COVID-19 and make full recovery

Most children and adolescents with cancer have mild COVID-19 disease and make a full recovery, a new study has found. But pediatric cancer patients with underlying health conditions, severe infections and low white blood cell counts were significantly more likely to have severe disease.

9 Nov 2021

Elusive white blood cells play a role in impaired T cell functions and counts in people with HIV

In a groundbreaking study of people living with HIV, University of Alberta researchers found that elusive white blood cells called neutrophils play a role in impaired T cell functions and counts, as well as the associated chronic inflammation that is common with the virus.

9 Nov 2021

The role of T follicular helper cells in the humoral immune response to SARS-CoV-2

The current analysis indicates that cTfh cells react to the spike antigen following vaccination are associated with anti-S protein neutralizing antibodies.

9 Nov 2021

Researchers explain why decaying SARS-CoV-2 antibodies in blood are not a problem after vaccination

A new study published in the preprint bioRxiv* server suggests vaccination helps to inflate the number of somatic hypermutations acquired by B cells. The increase in somatic hypermutations allows for an accumulation of highly matured bone marrow plasma cells.

8 Nov 2021

Oral drug works just as well as conventional therapy for anemia in patients with kidney disease

Anemia is a common and sometimes debilitating problem among patients with chronic kidney disease (CKD). Anemia can occur when the kidneys become damaged, limiting the production of erythropoietin (EPO) - a hormone that signals to the body to make red blood cells.

7 Nov 2021

Study discovers how the immune system triggers an 'emergency' dendritic cell response during infection

Scientists at the Francis Crick Institute have found how the immune system triggers an 'emergency' dendritic cell response during infection, with dendritic cells at the site of infection being reinforced by new cells which travel from the bone marrow.

6 Nov 2021

Effectiveness of mRNA BNT162b2 COVID-19 vaccine in immunocompromised individuals

Israeli researchers evaluate the antibody response in ICPs to assess antibody-mediated immunity following vaccination with the Pfizer-BioNTech vaccine.

26 Oct 2021

New AI-based tool helps clinicians understand and better predict adverse effects of COVID-19

The symptoms and side effects of Covid-19 are scattered across a diagnostic spectrum. Some patients are asymptomatic or experience a mild immune response, while others report significant long-term illnesses, lasting complications, or suffer fatal outcomes.

22 Oct 2021

Interferon treatment coupled with bone marrow transplant reduces risk of leukemia recurrence

Researchers at the University of Michigan Health Rogel Cancer Center have identified a drug that, when given along with a bone marrow transplant, drops the risk of leukemia recurring by 20% among the high-risk patients.

21 Oct 2021

Washington University receives $7.5 million to support NIH's research on senescent cells

Washington University School of Medicine in St. Louis is joining the National Institutes of Health's new research network focused on the study of senescent cells, a rare and important population of cells that is difficult to study but vital for understanding aging and the diseases of aging, including cancer and neurodegeneration.

20 Oct 2021

New findings may help widen therapeutic interventions for B-cell acute lymphoblastic leukemia

A retrospective study led by Northwestern Medicine investigators found that the chimeric antigen receptor (CAR) T-cell immunotherapy drug tisagenlecleucel demonstrated safety and efficacy in pediatric patients with relapsed and refractory B-cell acute lymphoblastic leukemia (B-cell ALL), even when the drug doesn't meet the FDA's strict manufacturing standards.

19 Oct 2021

Researchers report long-lasting effects of gene therapy in children with deadly immune disorder

Over a decade ago, UCLA physician-scientists began using a pioneering gene therapy they developed to treat children born with a rare and deadly immune system disorder.

18 Oct 2021

RUDN study reveals macrophage dynamics in the regenerating liver after resection

RUDN University discovered the features of liver macrophages activation during its regeneration. In future, it can be used to develop new treatment methods for liver cirrhosis. The results are published in the Biomedicine.

15 Oct 2021

SARS-CoV-2 induces tissue immune memory

A new study reports that the SARS-CoV-2 induces protective tissue memory that includes both humoral and cellular elements to protect specific tissue sites.

14 Oct 2021

Study shows how tissue-derived T cells can damage other organs in stem cell transplant patients

More than 40,000 allogeneic hematopoietic stem cell transplants are carried out worldwide every year, mostly for patients suffering from leukemia or other diseases of the hematopoietic system.

13 Oct 2021

Anti-rheumatic drug as a potential candidate for treating COVID-19

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) produces inflammatory cytokine storms. But an FDA-approved anti-rheumatic drug, Auranofin, used to treat autoimmune and infectious diseases, may also help serve as an antiviral treatment for COVID-19 infection.

13 Oct 2021

Vaccinated children induced significantly higher antibody titers than naturally SARS-CoV-2 infected children

A recent preprint discusses the antibody response to the nucleic acid vaccines against SARS-CoV-2 when administered to children aged 7-11 years.

12 Oct 2021

$Researchers identify a stem cell population with enhanced fracture healing and differentiation abilities$

Bone Marrow News and Research

Further Reading

Study: Most pediatric cancer patients have mild COVID-19 and make full recovery

Elusive white blood cells play a role in impaired T cell functions and counts in people with HIV

The role of T follicular helper cells in the humoral immune response to SARS-CoV-2

Researchers explain why decaying SARS-CoV-2 antibodies in blood are not a problem after vaccination

Oral drug works just as well as conventional therapy for anemia in patients with kidney disease

Study discovers how the immune system triggers an 'emergency' dendritic cell response during infection

Effectiveness of mRNA BNT162b2 COVID-19 vaccine in immunocompromised individuals

New AI-based tool helps clinicians understand and better predict adverse effects of COVID-19

Interferon treatment coupled with bone marrow transplant reduces risk of leukemia recurrence

Washington University receives $7.5 million to support NIH's research on senescent cells

New findings may help widen therapeutic interventions for B-cell acute lymphoblastic leukemia

Researchers report long-lasting effects of gene therapy in children with deadly immune disorder

RUDN study reveals macrophage dynamics in the regenerating liver after resection

SARS-CoV-2 induces tissue immune memory

Study shows how tissue-derived T cells can damage other organs in stem cell transplant patients

Anti-rheumatic drug as a potential candidate for treating COVID-19

Vaccinated children induced significantly higher antibody titers than naturally SARS-CoV-2 infected children

Researchers identify a stem cell population with enhanced fracture healing and differentiation abilities

Hollings Cancer Center researcher awarded NCI grant to pursue early investigator studies in leukemia

Persistent leukocyte changes three months after mild SARS-CoV-2 infection

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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