Clinical Trial News and Research

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Azelastine nasal spray prevents COVID-19 and rhinovirus infections

Researchers discuss the effects of azelastine nasal spray on the rate of SARS-CoV-2 infection as compared to placebo.

6 Oct 2025

Simple tools increase pediatrician compliance with early peanut allergy prevention guidelines

A few easy-to-implement tools - a training video, electronic health record prompts and handouts for families - greatly increased how often pediatricians recommended early peanut introduction to infants, reports a new clinical study led by Northwestern University and Ann & Robert H. Lurie Children's Hospital of Chicago.

6 Oct 2025

Study reveals new strategy to block TNBC metastasis and restore chromosomal stability

Triple negative breast cancer (TNBC) is one of the most aggressive and hardest forms of breast cancer to treat, but a new study led by Weill Cornell Medicine suggests a surprising way to stop it from spreading. Researchers have discovered that an enzyme called EZH2 drives TNBC cells to divide abnormally, which enables them to relocate to distant organs.

6 Oct 2025

Innovative topical cream relieves chemotherapy-induced peripheral neuropathy

Most patients receiving chemotherapy with taxanes or platinum salts develop pain and loss of sensitivity in their hands and feet—a severe side effect that can interfere with proper treatment.

3 Oct 2025

How gluten harms some people but helps others

New insights reveal gluten's health potential, highlighting beneficial peptides and innovative methods to enhance wheat safety for sensitive individuals.

3 Oct 2025

New study shows why HIV health recovery fails despite antiretroviral therapy

What if the presence of a well-known but misunderstood viral protein explains why some people living with HIV (PLWH) never recover their health, even with antiretroviral treatment?

3 Oct 2025

Study uncovers cerebellar involvement and social impairment

Spinal muscular atrophy is a rare genetic disease of the nerve cells in the spinal cord that can appear as early as infancy. The disease leads to a progressive loss of muscle strength. Those affected often suffer from muscle weakness early on, as well as difficulties with movement, breathing, and swallowing.

3 Oct 2025

Hippocrates study launches to address post-surgical health inequalities

A £2.8 million grant to combat health inequalities in patients having major surgery has been awarded to a team of clinicians and researchers at UCL and UCLH.

2 Oct 2025

Wearable device can help lower relapse risk in early addiction recovery

A new study by investigators from Mass General Brigham shows that a non-drug, wearable device can help people with substance use disorders (SUD) manage stress, reduce cravings, and lower their risk of relapse in real time.

2 Oct 2025

New study reveals molecular basis of Long COVID brain fog

Even though many years have passed since the start of the COVID-19 pandemic, the effects of infection with SARS-CoV-2 are not completely understood.

30 Sep 2025

Early trial finds promise for avelumab and radiation in treating leptomeningeal disease

Researchers at Moffitt Cancer Center have reported encouraging results from a phase 1B clinical trial showing that the immunotherapy drug avelumab, when combined with whole brain radiotherapy, may provide a safe and effective treatment option for patients with leptomeningeal disease, one of the most aggressive and difficult-to-treat complications of advanced cancer.

30 Sep 2025

Sotatercept shows strong benefits for newly diagnosed pulmonary hypertension patients

Prescribing the biologic drug sotatercept alongside standard treatment for the most severe form of pulmonary hypertension significantly reduces the likelihood of worsening disease when added within the first year after diagnosis, according to a study published in the New England Journal of Medicine.

30 Sep 2025

Harnessing “DNA surgery” to develop therapeutic medicines for genetic liver and heart diseases

Genome editing is increasingly recognized as a leading frontier in biomedical research and an essential driver of healthcare innovation.

30 Sep 2025

Digital tools and chatbots can expand genetic counseling for young cancer survivors

A groundbreaking new study from the Alliance for Clinical Trials in Oncology aims to test whether digital tools and chatbot technology can help young adult cancer survivors get the genetic counseling they need to better understand future health risks to themselves and family members.

30 Sep 2025

Cannabis extract eases chronic back pain and improves quality of life in major clinical trial

A phase 3 trial in Nature Medicine found that a full-spectrum Cannabis sativa extract (VER-01) significantly reduced chronic low back pain and improved sleep and function compared with placebo. The extract was safe, well-tolerated, and showed no signs of abuse or dependence, with benefits maintained over long-term treatment.

30 Sep 2025

Randomized trial shows exercise benefits for post-COVID immune regulation

Exercise can help to restore a more normal, well-regulated immune system in people with post-COVID syndrome, according to a gold-standard randomised-controlled trial presented at the European Respiratory Society Congress in Amsterdam, the Netherlands.

30 Sep 2025

Stereotactic radiotherapy offers long-term survival outcomes comparable to surgery for NSCLC patients

A new clinical trial report finds that stereotactic radiation therapy offers long-term survival outcomes comparable to surgery for patients with small, early-stage non-small cell lung cancer (NSCLC). Patients in the study who received radiation also reported fewer side effects after treatment.

30 Sep 2025

Proton therapy and IMRT show similar outcomes in head and neck cancer trial

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Clinical Trial News and Research

Azelastine nasal spray prevents COVID-19 and rhinovirus infections

Simple tools increase pediatrician compliance with early peanut allergy prevention guidelines

Study reveals new strategy to block TNBC metastasis and restore chromosomal stability

Innovative topical cream relieves chemotherapy-induced peripheral neuropathy

How gluten harms some people but helps others

New study shows why HIV health recovery fails despite antiretroviral therapy

Study uncovers cerebellar involvement and social impairment

Hippocrates study launches to address post-surgical health inequalities

Wearable device can help lower relapse risk in early addiction recovery

New study reveals molecular basis of Long COVID brain fog

Early trial finds promise for avelumab and radiation in treating leptomeningeal disease

Sotatercept shows strong benefits for newly diagnosed pulmonary hypertension patients

Harnessing “DNA surgery” to develop therapeutic medicines for genetic liver and heart diseases

Digital tools and chatbots can expand genetic counseling for young cancer survivors

Cannabis extract eases chronic back pain and improves quality of life in major clinical trial

Randomized trial shows exercise benefits for post-COVID immune regulation

Stereotactic radiotherapy offers long-term survival outcomes comparable to surgery for NSCLC patients

Proton therapy and IMRT show similar outcomes in head and neck cancer trial

Remote motivational counseling and mobile-based support help parents use safer car seats

Singing helps patients with COPD and interstitial lung disease

eBook: Using iPSCs models for human disease research and drug discovery eBook

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