Malignant News and Research

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Monoclonal antibodies may reduce hospital stay, but not mortality in COVID-19

A new study explores the real-world efficacy of monoclonal antibodies against COVID-19 in averting severe disease.

27 Sep 2021

New imaging technology for detecting MALT lymphomas could save patients numerous gastroscopies

A new imaging technique for the detection of MALT lymphomas, malignant tumours of the lymphatic system, could probably save patients numerous gastroscopies. A study group of MedUni Wien achieved a high imaging accuracy by way of PET/MR and by using a PET Tracer directed against a certain cell receptor. The results are currently published in the top journal "Blood" of the American Society of Hematology.

24 Sep 2021

New discovery offers clues to overcoming resistance to cancer therapies

Cancer cells proliferate despite a myriad of stresses - from oxygen deprivation to chemotherapy - that would kill any ordinary cell.

23 Sep 2021

New discovery may offer a promising avenue for study of multiple sclerosis

A surprising discovery may offer a promising new direction in the study of multiple sclerosis and other diseases of hypomyelination – when axons of neurons are not covered sufficiently in fatty sheaths (myelin), which disrupts communication between nerve cells.

23 Sep 2021

Sex, age are crucial factors in the care and survival of patients with malignant brain tumors

Findings from a national study by researchers at Translational Genomics Research Institute (TGen), an affiliate of City of Hope, and external collaborators suggest that sex and age are crucial factors in the care and survival of patients with malignant brain tumors and other central nervous systems (CNS) cancers.

23 Sep 2021

Study findings could lead to novel ways to overcome tumor resistance to immunotherapies

Cancer-fighting immune cells in patients with lung cancer whose tumors do not respond to immunotherapies appear to be running on a different "program" that makes them less effective than immune cells in patients whose cancers respond to these immune treatments, suggests a new study led by researchers at the Johns Hopkins Kimmel Cancer Center Bloomberg~Kimmel Institute for Cancer Immunotherapy.

22 Sep 2021

Researchers reveal a mechanism of SHP2-mediated tumor immunosuppression

Colorectal cancer (CRC), a malignant tumor worldwide consists of microsatellite instability (MSI) and stable (MSS) phenotypes. Although SHP2 is a hopeful target for cancer therapy, its relationship with innate immunosuppression remains elusive. To address that, the authors of this article performed single-cell RNA sequencing to explore the role of SHP2 in all cell types of tumor microenvironment (TME) from murine MC38 xenografts.

21 Sep 2021

Sunitinib extends progression-free survival in patients with rare neuroendocrine tumor, study shows

The first randomized study in malignant pheochromocytoma and paraganglioma (MPP) has found that sunitinib prolongs progression-free survival (PFS) by more than five months.

20 Sep 2021

Study uncovers a new way to counter immune suppression in tumors

Malignant tumors can enhance their ability to survive and spread by suppressing antitumor immune cells in their vicinity, but a study led by researchers at Weill Cornell Medicine and NewYork-Presbyterian has uncovered a new way to counter this immunosuppressive effect.

20 Sep 2021

AI can help with the diagnosis of B-cell lymphomas and related leukemias

The presence of cancer of the lymphatic system is often determined by analyzing samples from the blood or bone marrow.

18 Sep 2021

Defective versions of tumor suppressor genes can help cancer cells evade the immune system

Hundreds of cancer-linked genes play a different role in causing disease than scientists had expected.

16 Sep 2021

Research reveals vital role of protein-coding gene in tumor development and immune therapy response

Researchers from the Case Comprehensive Cancer Center uncovered the potentially important role of the protein-coding gene, MYO10, in tumor development and immune therapy response. Their findings were published today in Science Advances.

16 Sep 2021

New genetic classifier can predict the sensitivity of neoadjuvant chemotherapy for breast cancer

A research team by Prof. YANG Wulin and DAI Haiming from the Hefei Institutes of Physical Science (HFIPS) of the Chinese Academy of Sciences recently proposed a genetic classifier that can predict the sensitivity of neoadjuvant chemotherapy for breast cancer in the field of tumor molecular markers.

15 Sep 2021

Researchers discover new pathway that makes drugs less effective in bowel cancer patients

Leading scientists at the University of Birmingham have discovered a previously unknown pathway that prevents specific drugs from working in patients with bowel cancer.

14 Sep 2021

Analysis finds untapped potential for immunotherapy in older cancer patients

A retrospective analysis of large datasets of biomarkers from tumors and healthy tissue by researchers at the Johns Hopkins Kimmel Cancer Center Convergence Institute suggests that older cancer patients could benefit as much as younger patients from cancer immunotherapies.

13 Sep 2021

Malignant News and Research

Monoclonal antibodies may reduce hospital stay, but not mortality in COVID-19

New imaging technology for detecting MALT lymphomas could save patients numerous gastroscopies

New discovery offers clues to overcoming resistance to cancer therapies

New discovery may offer a promising avenue for study of multiple sclerosis

Sex, age are crucial factors in the care and survival of patients with malignant brain tumors

Study findings could lead to novel ways to overcome tumor resistance to immunotherapies

Researchers reveal a mechanism of SHP2-mediated tumor immunosuppression

Sunitinib extends progression-free survival in patients with rare neuroendocrine tumor, study shows

Study uncovers a new way to counter immune suppression in tumors

AI can help with the diagnosis of B-cell lymphomas and related leukemias

Defective versions of tumor suppressor genes can help cancer cells evade the immune system

Research reveals vital role of protein-coding gene in tumor development and immune therapy response

New genetic classifier can predict the sensitivity of neoadjuvant chemotherapy for breast cancer

Researchers discover new pathway that makes drugs less effective in bowel cancer patients

Analysis finds untapped potential for immunotherapy in older cancer patients

Study finds significant variability in treatment access for patients with malignant pleural mesothelioma

Cellular program could turn T cells into effective cancer killers

Self-correcting genetic mutations may protect patients with shortened telomeres from blood cancers

Study: Nearly one in five patients with malignant pleural mesothelioma contracted COVID-19

AI can spot signs of lung cancer on CT scans a year earlier

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