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Revolutionizing diabetes care: tPBM therapy proves effective in restoring microglial health

Transcranial photobiomodulation (tPBM) treatment affected insulin therapy on microglial function.

12 Dec 2023

Study identifies key factor in lung and eye damage in preemies

Advancements in the care of premature babies are leading to improved survival rates. However, the incidence of neonatal diseases with life-long consequences such as bronchopulmonary dysplasia (BPD) and retinopathy of prematurity (ROP) is increasing.

11 Dec 2023

MIT scientists develop nanoparticles to reduce inflammation in the brain

Some Covid-19 vaccines safely and effectively used lipid nanoparticles (LNPs) to deliver messenger RNA to cells. A new MIT study shows that different nanoparticles could be used for a potential Alzheimer's disease (AD) therapy.

11 Dec 2023

VUB researchers develop a nanobody-based technology to prevent liver inflammation

Mathieu Vinken, a professor in the In Vitro Toxicology and Dermato-cosmetology (IVTD) lab at the Vrije Universiteit Brussel, and doctoral student Raf Van Campenhout have developed a technique based on nanobody technology to prevent liver inflammation.

8 Dec 2023

Study may shed light on new ways to counteract the effects of high blood pressure on cognition

A study supported by the National Institutes of Health suggests that the response of immune system cells inside the protective covering surrounding the brain may contribute to the cognitive decline that can occur in a person with chronic high blood pressure.

5 Dec 2023

Postpartum phagocytosis of pancreatic β-cells by macrophages regulates blood glucose levels

Pancreatic beta cells (β-cells) reside in a cluster of cells in the pancreas known as the islets of Langerhans.

4 Dec 2023

Pancreatic vagus nerve stimulation boosts insulin production in mice

Insulin is a hormone that decreases blood glucose levels. The only cells that produce insulin are pancreatic beta cells (β-cells), and a decrease in these cells is a major cause of diabetes.

4 Dec 2023

LysoPI lipids show promise in boosting insulin secretion in diabetics

While sugar is the most frequently named culprit in the development of type 2 diabetes, a better understanding of the role of fats is also essential.

4 Dec 2023

Gut microbe Lactobacillus found to bolster stress resilience, new study reveals

Study demonstrates that the gut microbe Lactobacillus helps maintain normal levels of the cytokine interferon-gamma (IFNγ), providing protection against stress-induced disruptions in a mouse model. The findings suggest Lactobacillus's crucial role in building resilience to environmental stressors, highlighting its potential in treating mood disorders.

3 Dec 2023

Scientists unlock secrets of preeclampsia

Preeclampsia is a mysterious condition that occurs in about one of 10 pregnancies without any early warning signs.

1 Dec 2023

New insights into evolution of the “little brain”

The evolution of higher cognitive functions in human beings has so far mostly been linked to the expansion of the neocortex – a region of the brain that is responsible, inter alia, for conscious thought, movement and sensory perception.

29 Nov 2023

Researchers discover how rapid tendon regeneration occurs in newts

A research group led by Nagoya University's Graduate School of Engineering has uncovered how rapid tendon regeneration occurs in newts.

28 Nov 2023

Link between stress and autoimmunity: New insights into depression from mice to humans

Study investigates the link between stress and autoimmunity, finding a correlation between higher levels of serum and brain-reactive antibodies and depression-like behaviors in mice and humans with Major Depressive Disorder.

28 Nov 2023

Researchers discover way to reverse brain aging caused by COVID-19

University of Queensland researchers have found a way to reverse a cellular process triggered by COVID-19 that contributes to premature aging of the brain.

22 Nov 2023

Study shows how probiotic Bifidobacteria longum can help relieve constipation

Scientists have identified the genes in the probiotic Bifidobacteria longum responsible for improving gut motility.

21 Nov 2023

Brain's response to unexpected visual patterns evolves over time

Faced with images that break the expected pattern, like a do not enter sign where a stop sign is expected, how does the brain react and learn compared to being shown images which match what was predicted?

21 Nov 2023

Breakthrough in HIV treatment: NMN shows promise in reducing CD4+ T cell activation

The impact of nicotinamide mononucleotide (NMN) on Clusters of differentiation 4+ (CD4+ ) Thymus cells (T cells) viz.

21 Nov 2023

Study highlights glycolysis as a potential therapeutic target to combat Mycobacterium tuberculosis

It has been uncertain how Mycobacterium tuberculosis deflects the immune response in humans, though evidence has pointed to host immunometabolism - the intrinsic link between metabolism in immune cells and their immune function.

20 Nov 2023

Photobiomodulation in Alzheimer's mouse model falls short in preventive impact

Study assesses the effectiveness of photobiomodulation (PBM) treatment in a mouse model of Alzheimer's disease and finds no significant impact on behavioral performance or neurodegeneration, suggesting the need for further research into PBM's therapeutic potential.

16 Nov 2023

New vaccine promotes immune regulation that treats autoimmunity and prolongs transplant survival

A subtype of CD8 T cells, which are classically known to promote immune system responses, may be in fact regulating the immune system by suppressing immune cells causing self-destructive responses leading to autoimmune disorders and organ graft rejection.

15 Nov 2023

Mouse Model News and Research

Revolutionizing diabetes care: tPBM therapy proves effective in restoring microglial health

Study identifies key factor in lung and eye damage in preemies

MIT scientists develop nanoparticles to reduce inflammation in the brain

VUB researchers develop a nanobody-based technology to prevent liver inflammation

Study may shed light on new ways to counteract the effects of high blood pressure on cognition

Postpartum phagocytosis of pancreatic β-cells by macrophages regulates blood glucose levels

Pancreatic vagus nerve stimulation boosts insulin production in mice

LysoPI lipids show promise in boosting insulin secretion in diabetics

Gut microbe Lactobacillus found to bolster stress resilience, new study reveals

Scientists unlock secrets of preeclampsia

New insights into evolution of the “little brain”

Researchers discover how rapid tendon regeneration occurs in newts

Link between stress and autoimmunity: New insights into depression from mice to humans

Researchers discover way to reverse brain aging caused by COVID-19

Study shows how probiotic Bifidobacteria longum can help relieve constipation

Brain's response to unexpected visual patterns evolves over time

Breakthrough in HIV treatment: NMN shows promise in reducing CD4+ T cell activation

Study highlights glycolysis as a potential therapeutic target to combat Mycobacterium tuberculosis

Photobiomodulation in Alzheimer's mouse model falls short in preventive impact

New vaccine promotes immune regulation that treats autoimmunity and prolongs transplant survival

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