Respiratory Disease News and Research

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Vaccination more reliable than observation for bovine herpesvirus

Vaccination halts the circulation of bovine herpesvirus type 1 in dairy herds and should been seen as the best way to eradicate the virus, despite it disappearing without intervention in some herds after long periods, report researchers in the Veterinary Record.

18 Jul 2012

Vitamin D deficiency may impair lung function in asthmatic children treated with budesonide

Vitamin D deficiency is associated with poorer lung function in asthmatic children treated with inhaled corticosteroids, according to a new study from researchers in Boston.

14 Jul 2012

Swine-flu deaths far greater than reported

The true number of deaths from the 2009 H1N1 “swine flu” pandemic may be 15 times higher than the number confirmed by laboratory testing and previously reported to the World Health Organization, study findings indicate.

28 Jun 2012

Civitas commences CVT-301 Phase 2a trial in Parkinson's disease

Civitas Therapeutics, Inc., a privately-held pharmaceutical company developing transformative therapeutics using the ARCUS respiratory delivery platform, announced today the initiation of a Phase 2a clinical trial in Parkinson's disease patients evaluating CVT-301, an inhaled formulation of levodopa (L-dopa), for the rapid relief from motor fluctuations.

16 Jun 2012

OSA independently linked with DPN in patients with type 2 diabetes mellitus

Obstructive sleep apnea (OSA) is independently associated with diabetic peripheral neuropathy (DPN) in patients with type 2 diabetes mellitus (T2DM), according to a new study from researchers in the UK. The severity of DPN is also correlated with the degree of OSA and the severity of nocturnal hypoxemia.

15 Jun 2012

ORMC offers bronchial thermoplasty for severe asthma

Doctors at Orlando Regional Medical Center (ORMC) are delivering heat directly to the source to treat patients with severe asthma - a respiratory disease that causes the airways in the lungs to narrow, making it difficult to breathe.

13 Jun 2012

CSL Behring rIX-FP granted Orphan Drug Designation to treat hemophilia B

CSL Behring announced today that the company has been granted Orphan Drug Designation by the United States Food and Drug Administration for its novel recombinant fusion protein linking coagulation factor IX with recombinant albumin (rIX-FP).

8 Jun 2012

High levels of antibody molecule linked to increased rates of death from all diseases

Mayo Clinic researchers have identified an immune system deficiency whose presence shows someone is up to four times likelier to die than a person without it. The glitch involves an antibody molecule called a free light chain; people whose immune systems produce too much of the molecule are far more likely to die of a life-threatening illness such as cancer, diabetes and cardiac and respiratory disease than those whose bodies make normal levels. The study is published in the June issue of Mayo Clinic Proceedings.

4 Jun 2012

FDA accepts CSL Behring’s 4-factor PCC BLA for standard review

CSL Behring today announced that the U.S. Food and Drug Administration (FDA) has accepted for standard review its Biologics License Application (BLA) for a human 4-factor prothrombin complex concentrate (PCC) for the urgent reversal of vitamin K-antagonist therapy (i.e., warfarin) in patients with acute major bleeding. If approved by the FDA, the CSL Behring 4-factor PCC would be the first agent of its kind available in the United States.

30 May 2012

Daily use of vitamin C by smoking pregnant woman improves pulmonary function in babies

Vitamin C supplementation in pregnant women who are unable to quit smoking significantly improves pulmonary function in their newborns, according to a new study.

23 May 2012

Acupuncture may improve dyspnea in COPD patients

According to a small clinical trial reported by investigators from Japan, acupuncture appears to be associated with improvement of dyspnea (labored breathing) on exertion, in patients with chronic obstructive pulmonary disease (COPD), according to a study published Online First by Archives of Internal Medicine, a JAMA Network publication.

14 May 2012

Researchers barcode different strains of influenza virus and HRSV

Dr Julian Hiscox and Dr John Barr of the University's Faculty of Biological Sciences are working with the Health Protection Agency Porton (HPA) to build a bank of molecular signatures that will help identify the severity of virus infection from characteristic changes seen in cells. Currently the team is barcoding different strains of influenza virus and human respiratory syncytial virus (HRSV) - a virus associated with the onset of asthma in young children.

14 May 2012

Long-term exposure to roadways linked with increased risk of death in patients with heart attack

Living close to a major highway poses a significant risk to heart attack survivors, reinforcing the need to isolate housing developments from heavy traffic areas, a Beth Israel Deaconess Medical Center study concludes.

8 May 2012

Positive results from Dainippon Sumitomo Pharma's LATUDA trials for bipolar I depression

Dainippon Sumitomo Pharma Co., Ltd. announced today results from two Phase 3 clinical trials designed to evaluate the efficacy and safety of LATUDA as adjunctive therapy and monotherapy, respectively, in patients with bipolar I depression (PREVAIL 1 and PREVAIL 2; PRogram to EValuate the Antidepressant Impact of Lurasidone).

7 May 2012

Scanning the evidence for evidence in RTIs: NPS webinar

Next week NPS will host its inaugural webinar for GPs looking at medical imaging in respiratory tract infections (RTIs). Forming part of the NPS campaign on antibiotic resistance, the webinar on 10 May enables GPs to engage with imaging experts in real-time and gain insights into when imaging is appropriate for RTIs.

4 May 2012

CSL Behring commences C1-INH phase I/II study in hereditary angioedema

CSL Behring announced today that it has initiated an international phase I/II study of a volume-reduced, subcutaneous formulation of C1-esterase inhibitor (C1-INH) concentrate in patients with hereditary angioedema.

4 May 2012

Comorbidities common among patients with COPD

Comorbidities are common among patients with chronic obstructive pulmonary disease (COPD), and a number of these comorbidities are independently associated with an increased mortality risk, according to a new study.

4 May 2012

London School of Hygiene & Tropical Medicine launches Centre for Global Non-Communicable Diseases

The Centre for Global Non-Communicable Diseases, a unique initiative that brings together researchers, policy makers, funders and patient advocacy groups worldwide to focus research and expertise on this growing global health challenge, is launched today (25 April) at the London School of Hygiene & Tropical Medicine.

25 Apr 2012

New drug can prevent exacerbations of asthma due to common cold: Trial report

For the tens of thousands of asthma sufferers in the UK there is a “breakthrough” drug that reduces complications caused by the common cold, it is claimed.

22 Apr 2012

Asthma treatment still inadequate in Australia

Writing in the latest edition of Australian Prescriber, Associate Professor Helen Reddel, research leader at the Woolcock Institute of Medical Research says many people are prescribed higher doses than necessary. Most people do not use their inhalers correctly, leading to poor clinical outcomes and wasted medicines.

15 Apr 2012