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Genomic study reveals Babesia duncani's pathogenicity and virulence

'Tis the season for hiking now that spring has arrived and temperatures are on the upswing. But with hikes come insect bites and on the increase in North America is babesiosis, a malaria-like disease spread especially between May and October by a tick.

13 Apr 2023

Changes to tumor DNA can help predict cancer's next move

Knowing whether a tumor might grow or spread to other parts of a patient’s body could be key to survival – and now scientists are one step closer to unlocking the ability to predict just that.

13 Apr 2023

Research reveals molecular features of rare mtDNA mutations

A high-throughput single-cell single-mitochondrial genome sequencing technology known as iMiGseq has provided new insights into mutations of mitochondrial DNA (mtDNA) and offers a platform for assessing mtDNA editing strategies and genetic diagnosis of embryos prior to their implantation.

13 Apr 2023

New treatment pathway identified for patients with idiopathic nephrotic syndrome

With funding from charity Kidney Research UK, Dr Carl May from Bristol Medical School and his team have identified a new treatment pathway for patients with non-genetic (idiopathic) nephrotic syndrome (INS), targeting a still unknown factor that causes the progression towards kidney failure.

13 Apr 2023

MHRA research evaluates two different approaches to cancer therapies

The report 'Antibody conjugates for targeted delivery of Toll-like receptor 9 agonist to the tumor tissue', published in the PLOS ONE journal, highlights MHRA research which showed that genetic engineering of antibodies used to activate and support the immune system against cancer leads to improvements in their reliability and effectiveness.

13 Apr 2023

New tool provides insight into the developmental history of certain immune cells

A new tool that can uncover the developmental history of certain immune cells is now freely available worldwide. The tool provides insights into the stages that immune cells go through in a healthy individual and how this can be impacted in disease.

13 Apr 2023

From Sanger Sequencing to the Human Genome Project: The Evolution of DNA Sequencing Technology

In this inspiring interview, we speak to Dr. Radoje Drmanac, co-founder of Complete Genomics, about the past, present, and future of genomics research.

From MGI 13 Apr 2023

Early-life gut microbial dysbiosis exacerbates colitis

A recent Research journal study investigated the role of microbiota linked to the anaerobic plasmalogen biosynthetic pathway in establishing intestinal homeostasis. The study hypothesized that the presence of pls [PlsA/R]-positive bacterial species and plasmalogen bestow valuable intestine homeostasis in early life.

13 Apr 2023

Thousands of unique arboviruses and flaviviruses identified from samples collected between 1954-2018

A recent article identifies the encephalitogenic viruses registered in Brazil over the past six decades.

12 Apr 2023

Researchers discover important drug target for preventing blood cancer

An international coalition of biomedical researchers co-led by Alexander Bick, MD, PhD, at Vanderbilt University Medical Center has determined a new way to measure the growth rate of precancerous clones of blood stem cells that one day could help doctors lower their patients' risk of blood cancer.

12 Apr 2023

Study provides direct evidence of adaptive evolution in the skin microbiome

Human skin is home to millions of microbes. One of these microbes, Staphylococcus aureus, is an opportunistic pathogen that can invade patches of skin affected by eczema, also known as atopic dermatitis.

12 Apr 2023

New potential therapeutic developed for diffuse intrinsic pontine glioma using ASO technology

Diffuse intrinsic pontine glioma (DIPG) is a lethal pediatric brain cancer that often kills within a year of diagnosis. Surgery is almost impossible because of the tumors' location.

12 Apr 2023

Cedars-Sinai Cancer collaborates on a streamlined clinical trial design in Pragmatica-Lung Study

Investigators from Cedars-Sinai Cancer are collaborating on a streamlined clinical trial design in a study called Pragmatica-Lung.

12 Apr 2023

Researchers use a quick, portable process to produce promising virus-fighting protein

A multidisciplinary research team has produced a promising virus-fighting protein using a quick, portable process that could be easily deployed at the source of a future virus outbreak.

12 Apr 2023

Pragmatica-Lung Study aims to increase accessibility to cancer clinical trials

The National Cancer Institute, part of the National Institutes of Health (NIH), has helped launch a phase 3 randomized clinical trial (NCT05633602) of a two-drug combination to treat patients with advanced non-small cell lung cancer (NSCLC).

12 Apr 2023

Unexpected discovery could inspire new strategies for preventing liver disease and cancer

Liver cancer is the third leading cause of cancer death and the sixth most common cancer type worldwide.

12 Apr 2023

Acylceramides and protein-bound ceramides are vital for the formation of oral barrier in mice

Acylceramides and protein-bound ceramides are vital for the formation of the oral barrier in mice, similar to their role in skin, protecting from infection.

12 Apr 2023

Researchers conduct experiments comparing de novo proteins with computer-generated proteins

Proteins are components of every cell. How they have changed in the course of evolution for the purpose of taking on new functions in the body, has long been a subject of research.

12 Apr 2023

The identification of vaccinee-derived antibodies with broad-spectrum Omicron neutralization activity

Reported the identification of a panel of vaccinee-derived antibodies with broad-spectrum neutralization activity.

12 Apr 2023

New organoid platform could make vaccine screening quicker and greatly reduce animal testing

Developing and testing new treatments or vaccines for humans almost always requires animal trials, but these experiments can sometimes take years to complete and can raise ethical concerns about the animals' treatment.

12 Apr 2023

B Cell News and Research

Genomic study reveals Babesia duncani's pathogenicity and virulence

Changes to tumor DNA can help predict cancer's next move

Research reveals molecular features of rare mtDNA mutations

New treatment pathway identified for patients with idiopathic nephrotic syndrome

MHRA research evaluates two different approaches to cancer therapies

New tool provides insight into the developmental history of certain immune cells

From Sanger Sequencing to the Human Genome Project: The Evolution of DNA Sequencing Technology

Early-life gut microbial dysbiosis exacerbates colitis

Thousands of unique arboviruses and flaviviruses identified from samples collected between 1954-2018

Researchers discover important drug target for preventing blood cancer

Study provides direct evidence of adaptive evolution in the skin microbiome

New potential therapeutic developed for diffuse intrinsic pontine glioma using ASO technology

Cedars-Sinai Cancer collaborates on a streamlined clinical trial design in Pragmatica-Lung Study

Researchers use a quick, portable process to produce promising virus-fighting protein

Pragmatica-Lung Study aims to increase accessibility to cancer clinical trials

Unexpected discovery could inspire new strategies for preventing liver disease and cancer

Acylceramides and protein-bound ceramides are vital for the formation of oral barrier in mice

Researchers conduct experiments comparing de novo proteins with computer-generated proteins

The identification of vaccinee-derived antibodies with broad-spectrum Omicron neutralization activity

New organoid platform could make vaccine screening quicker and greatly reduce animal testing

Immunology eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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