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Drug combinations could become first-line treatment for metastatic kidney cancer

A combination of two drugs - one of them an immunotherapy agent - could become a new standard, first-line treatment for patients with metastatic kidney cancer, says an investigator from Dana-Farber Cancer Institute, reporting results from a phase 3 clinical trial.

18 Feb 2019

New PET/CT tracer shows high detection rate for diagnosis of acute venous thromboembolism

A first-in-human study featured in the February issue of The Journal of Nuclear Medicine reports that the novel positron emission tomography/computed tomography tracer 18F-GP1 showed excellent image quality and a high detection rate for the diagnosis of acute venous thromboembolism.

18 Feb 2019

Study sheds new light on left ventricular dysfunction in ischemic heart disease

Ischemic heart disease is a growing cause of heart failure owing to the increasing prevalence of diabetes, hypertension, and obesity.

17 Feb 2019

Study finds genetic vulnerability to use of menthol cigarettes

A genetic variant found only in people of African descent significantly increases a smoker's preference for cigarettes containing menthol, a flavor additive.

15 Feb 2019

Immune checkpoint molecule protects against future development of cancer

A research team at the University of Louisville has discovered that an immune checkpoint molecule they developed for cancer immunotherapy, also protects against future development of multiple types of cancer when administered by itself.

15 Feb 2019

Moffitt researchers shed light on how CAR T cells function mechanistically

The scientific community has made great strides over the past decade in the development of a new class of cancer therapy called immunotherapy, a treatment that activates a patient's own immune system to target cancer cells.

15 Feb 2019

New therapeutic molecules show promise in reversing memory loss related to depression, aging

New therapeutic molecules developed at Toronto's Centre for Addiction and Mental Health show promise in reversing the memory loss linked to depression and aging.

15 Feb 2019

Researchers use optogenetic tool to control, visualize receptor signals in neural cells

Using a novel optogenetic tool, researchers have successfully controlled, reproduced and visualized serotonin receptor signals in neural cells. To this end, they modified a photosensitive membrane receptor in the eye, namely melanopsin.

15 Feb 2019

Antidepressant drug could save people from deadly sepsis, research suggests

An antidepressant drug used to treat obsessive-compulsive disorder could save people from deadly sepsis, new research from the University of Virginia School of Medicine suggests.

14 Feb 2019

Blood-based liquid biopsies can accurately track cancer treatment responses

Results of two clinical studies have added to evidence that blood-based liquid biopsies can accurately track lung cancer treatment responses by measuring circulating tumor DNA (ctDNA) during immunotherapy and related treatments.

14 Feb 2019

Researchers comprehensively sequence the human immune system

For the first time ever, researchers are comprehensively sequencing the human immune system, which is billions of times larger than the human genome. In a new study published in Nature from the Human Vaccines Project, scientists have sequenced a key part of this vast and mysterious system -- the genes encoding the circulating B cell receptor repertoire.

14 Feb 2019

Sleep could be the best medicine to fight off an infection

Sleep has been underrated as the best medicine to fight off disease say researchers working on a new study. The study titled, “Gαs-Coupled Receptor Signaling and Sleep Regulate Integrin Activation of Human Antigen-Specific T Cells,” was published this week in the Journal of Experimental Medicine.

14 Feb 2019