Genomic News and Research

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Largest collection of autism DNA

Preliminary findings from the largest genome scan ever completed in the history of autism research are being published in Nature Genetics. University of Pittsburgh researchers with a consortium of scientists from across the world contributed to this landmark research endeavor through the Autism Genome Project.

18 Feb 2007

Researchers replace organ in mice using 'single-parent' stem cells

Researchers at the University of Pennsylvania School of Veterinary Medicine have derived uniparental embryonic stem cells - created from a single donor's eggs or two sperm - and, for the first time, successfully used them to repopulate a damaged organ with healthy cells in adult mice.

18 Feb 2007

Shortening chromosomes cause for earlier cancer onset in families with Li-Fraumeni syndrome

In families with a high incidence of Li-Fraumeni syndrome, the ends of individuals' chromosomes act somewhat like a lit fuse, according to researchers at The Hospital for Sick Children in Toronto. Their findings detail how telomeres, the ends of the chromosomes, shorten with every successive generation, leading to more severe cancers at an earlier age.

15 Feb 2007

DNA-encoded antibody libraries

During the past several years, breakthroughs in genomic and proteomic technologies have enabled researchers to more clearly identify the biochemical networks that malfunction when a healthy cell becomes malignant.

12 Feb 2007

African-American women three times more likely to deliver babies prematurely

African-American women are three times more likely to deliver babies three to 17 weeks prematurely than Caucasian women, according to a review of Missouri birth statistics by researchers at Washington University School of Medicine in St. Louis.

11 Feb 2007

International consortium to get to heart of coronary artery disease

An international consortium has been launched to tackle coronary artery disease using the latest scientific tools. Funded by the European Commission, the initiative will build on recent advances in genomic science and the understanding of our genes to develop effective strategies for preventing and treating the disease.

7 Feb 2007

Research helps explain origin of self-reactive B cells

Doctors have long wondered why, in some people, the immune system turns against parts of the body it is designed to protect, leading to autoimmune disease.

7 Feb 2007

Scientists step closer to understanding the relationship between aging and cancer

Wielding a palette of chromosome paints, scientists at the Salk Institute for Biological Studies have taken a step closer to understanding the relationship between aging and cancer by visualizing chromosomes of cells from patients with a heritable premature aging disease known as Werner Syndrome.

6 Feb 2007

Scientists test technique for identifying newly recognized DNA variations that may influence disease risk

Rather than focus on errors and alterations in DNA sequence, the new technique highlights variations in the number of copies of a particular gene.

30 Jan 2007

Hepatitis C virus replication in transfected and serum-infected cultured human fetal hepatocytes

Researchers open the way for improved study of hepatitis C virus by devising a novel virus culture system that allows replication of patient-isolated virus in nontransformed hepatocytes, instead of culture-adapted virus strains in transformed cell lines.

23 Jan 2007

Discovery of protein complex that plays important role in organ formation, cellular development and cicatrisation processes

Cellular movements are essential in organ formation processes, in cellular development and cicatrisation processes.

18 Jan 2007

Several specific genetic alterations associated with development of smoking-related cancers

Preliminary research indicates that several specific genetic alterations are associated with the development of smoking-related head and neck skin cancers, according to a report in the January 10 issue of JAMA: The Journal of the American Medical Association.

9 Jan 2007

BioMed Central launches BMC Systems Biology

BioMed Central has announced the launch of BMC Systems Biology, the first open access journal focussed solely on the entire emerging subject of systems biology.

8 Jan 2007

New genetic theory of parental teamwork

A molecular 'battle of the sexes' long considered the major driving force in a baby's development is being challenged by a new genetic theory of parental teamwork.

From The University of Manchester 2 Dec 2006

Further European investment in genomics

The Economic and Social Research Council (ESRC) has announced continued funding, from 2007 to 2012, for its three research centres, CESAGen, EGENIS and INNOGEN, that, along with the ESRC Genomics Policy and Research Forum, make up the ESRC Genomics Network.

23 Oct 2006