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Study findings hold promise for children with DMD

Prednisone, the current standard of care used to treat kids with Duchenne muscular dystrophy (DMD), reduces chronic inflammation but has harsh side effects.

11 Feb 2019

Bone marrow disease is stimulated by vitamin D and immune cells, reveals research

The bone marrow disease myelofibrosis is stimulated by excessive signaling from vitamin D and immune cells known as macrophages, reveals a Japanese research team. These findings could help to develop alternative treatments that do not target problem genes.

11 Feb 2019

New cancer drug that acts as ‘Trojan horse’ shows promise in patients with various cancers

A brand new type of cancer drug that acts as a 'Trojan horse' to get inside tumor cells has shown promise in patients with six different cancer types.

11 Feb 2019

OHSU research uncovers new target to prevent, treat alcoholism

New research conducted at OHSU in Portland, Oregon, identifies a gene that could provide a new target for developing medication to prevent and treat alcoholism.

11 Feb 2019

New research opens the way for tailored cancer drugs

New research on how cancer mutations influence a certain type of receptor on the cell membrane opens the way for the development of tailored drugs for certain cancers, such as rectal cancer and lung cancer.

11 Feb 2019

New simulations offer insights on vital atomic-scale drug-cardiac cells interactions

To unravel the mysterious mechanisms of drug potency for the treatment of cardiac arrhythmias, a group of researchers at UC Davis have developed novel simulations that provide insights on vital atomic-scale drug-cardiac cells interactions.

8 Feb 2019

Caltech scientists develop new methods for rapidly determining T cell targets

The human body's immune system is like a vast team of special agents. Certain cells called T cells each individually specialize in recognizing a particular intruder, such as the influenza virus or salmonella.

8 Feb 2019

Interaction between two immune cells may play key role in fight against dengue virus

Researchers at Duke-NUS Medical School have demonstrated for the first time a physical interaction between two types of immune cells that plays an important role in the early fight against dengue virus infection.

8 Feb 2019

Immunotherapy drug found to be effective in patients with advanced Merkel cell carcinoma

A multi-center phase II clinical trial investigating pembrolizumab as a first-line and programmed cell death-1 therapy in patients with advanced Merkel cell carcinoma reports lasting tumor control, generally manageable side effects and improved overall survival.

8 Feb 2019

Researchers reveal novel computational tool used to analyze genetic variation

The field of genetic sequencing has undergone a dramatic revolution over the past 20 years. In 2001 the first copy of the three billion base pairs that assemble the human genome was published.

8 Feb 2019

Scientists wean mosquitoes off blood with dieting drugs

Researchers have found a way to reduce the blood thirst of mosquitoes and prevent mosquito bites and spread of mosquito borne illnesses such as Zika, dengue fever, malaria and chikungunya.

7 Feb 2019

Study finds underutilization of aspirin to prevent colorectal cancer in high risk patients

Colorectal cancer is the third most common cause of cancer deaths in the United States and advanced colorectal polyps are a major risk factor.

7 Feb 2019

Cannabinoid receptor type 1 appears to be potential target to treat Down syndrome

A study by the Neuropharmacology Laboratory-NeuroPhar of the Department of Experimental and Health Sciences at UPF reveals the involvement of the endocannabinoid system in cognitive disorders in mouse models of Down syndrome.

7 Feb 2019

Simulation model to find the most optimal cancer treatment

In ten years, computers will be able to propose the most suitable cancer treatment for you. The idea is to simulate how all possible combinations of existing cancer treatments will work on your particular tumor.

6 Feb 2019

Researchers discover first sour taste receptor used by flies to choose between foods

Taste is so familiar a sensation that you might think scientists had long ago sorted out how the sense works. Yet such research is far from settled.

6 Feb 2019

Powerful immune molecule silences barrel to protect transplanted organs from rejection

A powerful immune molecule helps protect transplanted organs from rejection by putting a silencer on two other immune molecules that converge to take a direct shot at the organ, scientists report.

5 Feb 2019

Breast cancer risk highest two decades after childbirth finds study

According to new research, women are at a highest risk of breast cancer, more than two decades after having given birth. This finding comes along with another in a separate study that reveals that breast cancers occurring after childbirth are more likely to spread compared to breast cancers in women who never had children.

3 Feb 2019

New research may help treat HIV patients without elevating risk for liver disease

As a raft of new treatments for HIV infection have come on the market in the past 20 years, AIDS patients got access to drugs that allowed them to live longer.

1 Feb 2019

Study reveals how whipworms cause destruction in the gut

Signaling through interleukin-10 (IL-10) receptors on gut immune cells plays a critical role in protecting the gut lining and microbiota from disruption caused by whipworms, according to a study published January 31 in the open-access journal PLOS Pathogens by María Duque-Correa of the Wellcome Sanger Institute in the UK, and colleagues.

1 Feb 2019

Study: IL10 receptor critical to prevent uncontrolled infection and gut damage

A new study has identified the master regulator that maintains a healthy gut and limits damage by parasitic whipworms.

1 Feb 2019

Receptor News and Research

Study findings hold promise for children with DMD

Bone marrow disease is stimulated by vitamin D and immune cells, reveals research

New cancer drug that acts as ‘Trojan horse’ shows promise in patients with various cancers

OHSU research uncovers new target to prevent, treat alcoholism

New research opens the way for tailored cancer drugs

New simulations offer insights on vital atomic-scale drug-cardiac cells interactions

Caltech scientists develop new methods for rapidly determining T cell targets

Interaction between two immune cells may play key role in fight against dengue virus

Immunotherapy drug found to be effective in patients with advanced Merkel cell carcinoma

Researchers reveal novel computational tool used to analyze genetic variation

Scientists wean mosquitoes off blood with dieting drugs

Study finds underutilization of aspirin to prevent colorectal cancer in high risk patients

Cannabinoid receptor type 1 appears to be potential target to treat Down syndrome

Simulation model to find the most optimal cancer treatment

Researchers discover first sour taste receptor used by flies to choose between foods

Powerful immune molecule silences barrel to protect transplanted organs from rejection

Breast cancer risk highest two decades after childbirth finds study

New research may help treat HIV patients without elevating risk for liver disease

Study reveals how whipworms cause destruction in the gut

Study: IL10 receptor critical to prevent uncontrolled infection and gut damage

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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