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Cell membrane complexes may be new target for drugs to kill cancer cells

Old molecules and new complexes: researchers at Hollings Cancer Center at the Medical University of South Carolina have discovered cell membrane complexes called ceramidosomes that may be a new target for drugs to kill cancer cells.

13 Feb 2019

Researchers provide insight into how breast tissue stiffening promotes cancer development

A study provides new insight into how the stiffening of breast tissue plays a role in breast cancer development. By examining how mammary cells respond in a stiffness-changing hydrogel, bioengineers at the University of California San Diego discovered that several pathways work together to promote the transformation of breast cells into cancer cells.

13 Feb 2019

New mouse model replicates development and progression of Type I diabetes

Researchers at The University of Toledo have found a new way to replicate in lab mice the development and progression of Type I diabetes, a breakthrough that has the potential to reshape how the chronic disease is studied.

13 Feb 2019

Comparison of cancer genes across species helps prioritize targets for new cancer therapies

Cancer genes in mucosal melanoma, a rare and poorly understood subtype of melanoma, have been compared in humans, dogs and horses for the first time by scientists at the Wellcome Sanger Institute and their collaborators.

12 Feb 2019

New diagnostic technique reveals key protein biomarker for bladder cancer

Label-free digital pathology using infrared imaging with subsequent proteomic analysis for bladder cancer has revealed the first protein biomarker for BC. AHNAK2 differentiates between chronic cystitis (inflammation of the bladder) and a non-muscle invasive-type BC (carcinoma in situ) which is challenging to diagnose.

12 Feb 2019

Rare gene mutations associated with colorectal cancer also cause breast cancer

Rare mutations in the NTHL1 gene, previously associated with colorectal cancer, also cause breast cancer and other types of cancer.

12 Feb 2019

AbbVie, Teneobio enter into strategic transaction to develop potential treatment for multiple myeloma

AbbVie, Teneobio, Inc. and its affiliate TeneoOne, Inc. announced today that they have entered a global strategic transaction to develop and commercialize TNB-383B, a BCMA-targeting immunotherapeutic for the potential treatment of multiple myeloma.

12 Feb 2019

Researchers discover new therapeutic target for rare, aggressive pediatric cancers

Researchers at The University of Texas MD Anderson Cancer Center have discovered that malignant rhabdoid tumors, a rare pediatric cancer without effective treatments, may be sensitive to drugs that block the cancer cell's ability to dispose of misfolded proteins.

12 Feb 2019

UMN researchers develop new way to study cancer cells in a 3D in vitro model

University of Minnesota researchers have developed a way to study cancer cells which could lead to new and improved treatment. They have developed a new way to study these cells in a 3D in vitro model (i.e. in a culture dish rather than in a human or animal).

12 Feb 2019

Research reveals critical immunological axis that triggers cancer-promoting chronic inflammation

A Massachusetts General Hospital research team has identified interaction between two elements of the immune system as critical for the transformation of a protective immune response into chronic, cancer-promoting inflammation.

12 Feb 2019

New PET imaging agent may help measure efficacy or failure of hormone therapy for breast cancer

Physicians may soon have a new way to measure the efficacy or failure of hormone therapy for breast cancer patients, according to new research published in the February issue of The Journal of Nuclear Medicine.

12 Feb 2019

Immunotherapy drug can be effective in treating patients with recurrent brain tumors

A UCLA-led study suggests that for people with recurrent glioblastoma, administering an immunotherapy drug before surgery is more effective than using the drug afterward.

11 Feb 2019

Trojan Horse approach to cancer therapy shows promise

A new form of cancer fighting drug has been developed using the principles of the “Trojan Horse”.

11 Feb 2019

New model sheds light on how small cell lung cancer is initiated

Scientists from Weill Cornell Medicine have developed a stem-cell-based model of small cell lung cancer that will help them understand how the disease is initiated and how it progresses.

11 Feb 2019

New technique uses acoustic waves to measure the stiffness of living cells

MIT engineers have devised a new, noninvasive way to measure the stiffness of living cells using acoustic waves. Their technique allows them to monitor single cells over several generations and investigate how stiffness changes as cells go through the cell division cycle.

11 Feb 2019

Immunotherapy may be better than chemotherapy for Merkel cell carcinoma

The first study of the immunotherapy drug pembrolizumab as the initial treatment for patients with a rare but aggressive form of skin cancer known as Merkel cell carcinoma reports better responses and longer survival than expected with conventional chemotherapy.

11 Feb 2019

New findings could provide novel approach to target and destroy cancer cells

An unexpected finding in pre-clinical platelet studies by Baker Institute researchers could provide a novel approach to targeting and destroying difficult-to-treat cancer cells, providing new therapeutic options for a range of cancers.

11 Feb 2019

New cancer drug that acts as ‘Trojan horse’ shows promise in patients with various cancers

A brand new type of cancer drug that acts as a 'Trojan horse' to get inside tumor cells has shown promise in patients with six different cancer types.

11 Feb 2019

Research finds new potential targets for treatment of pancreatic cancer

The first study in the world to take a detailed look at scar tissue in human pancreatic cancer has revealed a range of different scar tissue types that could help clinicians predict which patients will respond best to particular treatments.

11 Feb 2019

Scientists create 3D-bioprinted brain model to study interaction with immune cells

Around a glioblastoma, a very aggressive brain tumor, cells of the human immune system start helping the tumor instead of attacking it. To do research on what happens in the interaction of these cells, scientists of the University of Twente now created a 3D-bioprinted mini model of the brain.

11 Feb 2019

Tumor News and Research

Cell membrane complexes may be new target for drugs to kill cancer cells

Researchers provide insight into how breast tissue stiffening promotes cancer development

New mouse model replicates development and progression of Type I diabetes

Comparison of cancer genes across species helps prioritize targets for new cancer therapies

New diagnostic technique reveals key protein biomarker for bladder cancer

Rare gene mutations associated with colorectal cancer also cause breast cancer

AbbVie, Teneobio enter into strategic transaction to develop potential treatment for multiple myeloma

Researchers discover new therapeutic target for rare, aggressive pediatric cancers

UMN researchers develop new way to study cancer cells in a 3D in vitro model

Research reveals critical immunological axis that triggers cancer-promoting chronic inflammation

New PET imaging agent may help measure efficacy or failure of hormone therapy for breast cancer

Immunotherapy drug can be effective in treating patients with recurrent brain tumors

Trojan Horse approach to cancer therapy shows promise

New model sheds light on how small cell lung cancer is initiated

New technique uses acoustic waves to measure the stiffness of living cells

Immunotherapy may be better than chemotherapy for Merkel cell carcinoma

New findings could provide novel approach to target and destroy cancer cells

New cancer drug that acts as ‘Trojan horse’ shows promise in patients with various cancers

Research finds new potential targets for treatment of pancreatic cancer

Scientists create 3D-bioprinted brain model to study interaction with immune cells

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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