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U of U develops small implantable middle-ear microphone

Cochlear implants have restored basic hearing to some 220,000 deaf people, yet a microphone and related electronics must be worn outside the head, raising reliability issues, preventing patients from swimming and creating social stigma.

30 Apr 2012

Study explores resilin-like materials for vocal fold disorders

A one-inch long grasshopper can leap a distance of about 20 inches. Cicadas can produce sound at about the same frequency as radio waves. Fleas measuring only millimeters can jump an astonishing 100 times their height in microseconds. How do they do it? They make use of a naturally occurring protein called resilin.

27 Apr 2012

FDA ODAC to review Onyx’s NDA for carfilzomib

Onyx Pharmaceuticals, Inc. today announced that the U.S. Food and Drug Administration's (FDA) Oncologic Drugs Advisory Committee (ODAC) will review the company's new drug application (NDA) for carfilzomib for the treatment of patients with relapsed and refractory multiple myeloma who have received at least two prior therapies. ODAC will review carfilzomib at its meeting on June 20, 2012.

27 Apr 2012

FDA issues Complete Response Letter to Amgen’s sBLA for XGEVA

Amgen today announced that the U.S. Food and Drug Administration (FDA) has issued a Complete Response Letter for the supplemental Biologics License Application (sBLA) for XGEVA (denosumab) to treat men with castration-resistant prostate cancer (CRPC) at high risk of developing bone metastases.

27 Apr 2012

Gamma and delta-tocopherols do prevent many cancers

Next time you need to choose between vegetable oil and margarine in that favorite recipe, think about your health and reach for the oil. While the question of whether vitamin E prevents or promotes cancer has been widely debated in scientific journals and in the news media, scientists at the Center for Cancer Prevention Research, at Rutgers Mario School of Pharmacy, and the Cancer Institute of New Jersey, believe that two forms of vitamin E - gamma and delta-tocopherols - found in soybean, canola and corn oils as well as nuts do prevent colon, lung, breast and prostate cancers.

27 Apr 2012

Mad cow disease raises concern but safety nets are in place says USDA

Four sick cows ever discovered in the U.S., the one announced Tuesday being the first since 2006, and no human version of the illness linked to eating U.S. beef, is not enough to worry about. “From simply a public health issue, I put it very, very low,” Cornell University food safety expert Martin Wiedmann said of the level of concern about mad cow disease. Maintaining confidence in exports fuels the nation's monitoring of the beef supply as much as continuing safety concerns, he said.

26 Apr 2012

AAA to gather for anatomy meeting in conjunction with Experimental Biology 2012

The American Association of Anatomists will gather this week for its annual meeting in conjunction with the Experimental Biology 2012 conference, which will draw more than 14,000 scientists from industry, government and academia. Below are some programming highlights for the anatomy meeting. All presentations will be made at the San Diego Convention Center.

26 Apr 2012

Robot assisted laparoscopic radical prostatectomy better than other surgical techniques

Outcomes from use of a robot to assist surgeons in removal of a cancerous prostate are at least as good, if not better, than the other two techniques used for a radical prostatectomy -- open or laparoscopic surgery -- according to a large meta analysis led by researchers at NewYork-Presbyterian/Weill Cornell.

26 Apr 2012

Gender differences in musculoskeletal health are not solely due to hormones

Osteoarthritis, osteoporosis, fractures, and spinal disorders are among the most common reasons for doctor visits. These conditions have more than one thing in common: they are all musculoskeletal problems and are more prevalent in women.

26 Apr 2012

Vitamin D supplementation in winter can help lower blood pressure in hypertensive patients

A new study, presented at the European Society of Hypertension meeting in London, shows that vitamin D supplementation in winter can help lower blood pressure in patients with hypertension.

25 Apr 2012

RANK inhibitor-chemotherapy combination may have important therapeutic effects against breast cancer

Researchers from the Bellvitge Biomedical Research Institute (IDIBELL) have shown that overactivation of the RANK signalling pathway promotes the initiation, progression and metastasis of tumours in human breast epithelial cells by dedifferentiation of breast cells to stem cells. The results of this study have been advanced in the electronic edition of the journal Cancer Research.

25 Apr 2012

ASH report urges federal agencies to invest in 7 distinct areas of research

The American Society of Hematology (ASH), the world's largest professional society committed to the study and treatment of blood disorders, today issued a report urging federal agencies to coordinate hematology research funding around seven specific high-need areas that would produce the greatest impact and translate into improvements in patient care in the United States.

25 Apr 2012

Vitamin D deficiency associated with increase in lung transplant rejection, infections

Vitamin D deficiency is associated with an increase in lung transplant rejection and infections, according to research conducted at Loyola University Health System.

25 Apr 2012

Amgen announces agreement to acquire Mustafa Nevzat

Amgen, the world's largest biotechnology company, and Mustafa Nevzat Pharmaceuticals (MN) today announced an agreement under which Amgen will acquire 95.6 percent of shares in MN, a privately held Turkish pharmaceutical company, for an amount that values MN at US $700 million.

25 Apr 2012

CML and B-ALL arise from the long-term haematopoietic stem cells

Although people generally talk about "cancer", it is clear that the disease occurs in a bewildering variety of forms. Even single groups of cancers, such as those of the white blood cells, may show widely differing properties. How do the various cancers arise and what factors determine their progression? Clues to these two issues, at least for leukaemias, have now been provided by Boris Kovacic and colleagues at the University of Veterinary Medicine, Vienna.

25 Apr 2012

Study points to positive health benefits of fibers

For years, fiber intake among the global population has been extremely low, setting the stage for potentially serious, long-term public health implications. New research commissioned by Tate & Lyle and presented at the 2012 Experimental Biology conference in San Diego adds to the body of emerging research on fibers, including additional support for the role of soluble corn fiber in bone health.

24 Apr 2012

Study investigates how vitamin D affects skeleton when serum calcium levels are depleted

Vitamin D is renowned for its role in creating strong bones and is a key regulator of serum calcium levels. Calcium is primarily obtained through diet and absorbed through the intestine and into the blood stream. In addition to building bone, calcium is required for a variety of important physiological processes. Vitamin D, which is detected by receptors in bone and intestinal cells, regulates the level of calcium in the blood stream and determines how much should be stored in the skeleton.

24 Apr 2012

New device can correct bone deformities in children

Another day, another four turns of the screw. That's just a part of life for people, primarily children, undergoing the long and difficult process of distraction osteogenesis, a method to correct bone deformities that leave one limb shorter than the other.

24 Apr 2012

Nephros granted rights to market products based on Medica's Medisulfone ultrafiltration technology

Nephros, Inc., a medical device company developing and marketing filtration products for therapeutic applications, infection control, and advanced water purification solutions, today announced that the company has entered into a strategic license and supply agreement with Medica S.p.A.

23 Apr 2012

Researchers identify genetic variations linked to osteoporosis

Researchers at the Sahlgrenska Academy at the University of Gothenburg, Sweden, have identified the genetic variations that are believed to cause osteoporosis.

23 Apr 2012