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Researchers find way to attack a process that tumor cells use to escape effects of cancer drugs

Cancer cells often devise ways to survive even in the presence of toxic chemotherapy. Now, a research team led by investigators at Beth Israel Deaconess Medical Center has found a way to attack a process that tumor cells use to escape the effects of standard cancer drugs. The discovery is published online today in the journal Nature Cell Biology.

19 Apr 2016

Royal Society of Medicine, ITN Productions jointly launch new initiative ‘Doctors of the Future’

In a unique communications partnership, the Royal Society of Medicine and ITN Productions have launched a news and current affairs-style programme.

19 Apr 2016

New research centre to tackle childhood obesity to be launched at University of Sydney’s CPC

A world-first research centre exclusively focused on tackling the childhood obesity epidemic will launch this week at the University of Sydney’s Charles Perkins Centre (CPC).

19 Apr 2016

Women with epilepsy have likelihood of achieving successful pregnancy just as healthy peers

Women with epilepsy are just as likely to achieve a successful pregnancy as women without the neurological disorder, according to a new study led by research teams at multiple centers, including NYU Langone Medical Center.

18 Apr 2016

New study to explore outcomes of pregnancy in Brazilian women with Zika virus

An observational study of pregnant women in Brazil to further understand Zika virus and its impact on reproductive health and fetus development have been launched. William Britt, M.D., professor of pediatric infectious diseases at the University of Alabama at Birmingham, leads the study, which complements his current research in Brazil on cytomegalovirus infection during pregnancy.

18 Apr 2016

MGH-led study confirms safety of allergy immunotherapy

A team of Massachusetts General Hospital investigators has found no evidence of infections related to administration of allergy immunotherapy, the common practice of injecting minimal quantities of allergens beneath the skin to reduce the allergic response.

18 Apr 2016

How will IoT impact healthcare? An interview with David Doherty

IoT is a term being used to help communicate the complex transition that's happening as Mobile transforms the Internet into a network of devices. The idea of the internet being something we go to and use a mouse to navigate is dead as we now can talk to SIRI on our mobiles to immediately summon Uber cars and buy things from Amazon that will arrive in just a few hours. Welcome to a new world!

18 Apr 2016

Study supports screening for HLA-B*5801 gene variant in Asian, black patients with gout

A multi-institutional study led by a Massachusetts General Hospital investigator finds significant racial disparities in the risk that patients being treated for gout will develop a serious, sometimes life-threatening adverse reaction to the most commonly prescribed medication. The increased risk closely correlates with the frequency of a gene variant previously associated with that adverse reaction, supporting recommendations to screen for that variant in patients from those populations.

16 Apr 2016

International panel reclassifies a type of thyroid tumor to reduce cancer overdiagnosis

Led by researchers at the University of Pittsburgh School of Medicine, an international panel of pathologists and clinicians has reclassified a type of thyroid cancer to reflect that it is noninvasive and has a low risk of recurrence. The name change, described today in JAMA Oncology, is expected to reduce the psychological and medical consequences of a cancer diagnosis, potentially affecting thousands of people worldwide.

16 Apr 2016

Investigators find tacrolimus to be very effective in reducing ocular symptoms of GVHD

Researchers from Massachusetts Eye and Ear/Harvard Medical School have conducted a clinical trial comparing the safety and efficacy of topical tacrolimus, an immunosuppressive therapy, and topical methylprednisolone, a steroid medication, in patients with ocular graft-versus-host-disease (GVHD) -- a complication associated with allogeneic bone marrow transplants in which the transplanted immune system's cells attack certain parts of the recipient's body, including the cornea and ocular surface.

16 Apr 2016

Removal of Dnmt1 enzyme during OPC differentiation could lead to neurological symptoms

The removal of the enzyme Dnmt1 during oligodendrocyte progenitor cell (OPC) differentiation in the central nervous system resulted in inefficient myelin formation and neurological deterioration, including loss of control of bodily movements, in mice, according to a study conducted at the Icahn School of Medicine at Mount Sinai and published today in the medical journal Cell Reports. The results could lead to a new understanding of multiple sclerosis and other myelin disorders in humans.

16 Apr 2016

Adolescent obesity linked to elevated risk of cardiovascular mortality in midlife

A nationwide study of 2.3 million Israeli adolescents, examined from 1967 through 2010, finds an association between elevated body-mass index in late adolescence, and subsequent cardiovascular mortality in midlife.

16 Apr 2016

Scientists identify key pathway that regulates 'switch' between wakefulness and sleep

Falling asleep and waking up are key transitions in everyone's day. Millions of people have trouble with these transitions - they find it hard to fall asleep or stay asleep at night, and hard to stay awake during the day. Despite decades of research, how these transitions work - the neurobiological mechanics of our circadian rhythm - has remained largely a mystery to brain scientists.

16 Apr 2016

Slow-wave sleep may promote consolidation of recent memories

Research strongly suggests that sleep, which constitutes about a third of our lives, is crucial for learning and forming long-term memories. But exactly how such memory is formed is not well understood and remains, despite considerable research, a central question of inquiry in neuroscience.

16 Apr 2016

Expanding insurance coverage for elective single-embryo transfer could result in ideal pregnancy outcomes

Expanding insurance coverage for a type of in vitro fertilization known as elective single-embryo transfer could lead to improved health outcomes and lower health care costs, according to a newly published study that included researchers from the University of Colorado School of Medicine.

15 Apr 2016

Growth chart of brain networks could spot early signs of attention difficulties in children

Want to know if your child's height and weight are on track? Check the growth chart that the doctor gives you after each yearly checkup.

15 Apr 2016

VIEKIRAX and EXVIERA achieve high SVR rates in GT1 and GT4 hepatitis C virus infected patients

AbbVie, a global biopharmaceutical company, today announced new real-world data showing 96 percent of genotype 1 (GT1) patients (n=486/505 assessable for analysis) and 100 percent (n=53/53) of genotype 4 (GT4) patients achieved sustained virologic response at 12 weeks post-treatment (SVR12).

15 Apr 2016

Improving body clock could protect against metabolic syndrome

Essential biological processes are managed by an internal timer or body clock. When the body clock gets out of whack, conditions such as metabolic syndrome can occur.

15 Apr 2016

M10 peptide could help protect systemic sclerosis patients against fibrotic damage

The results of preclinical studies by investigators at the Medical University of South Carolina (MUSC) reported in the April 2016 issue of Translational Research suggest that the M10 peptide could help protect against fibrotic damage in patients with systemic sclerosis, particularly in those who develop interstitial lung diseases (ILD), its deadliest complication.

15 Apr 2016

Researchers develop novel method to store microfluidic devices for CD4 T cell testing

Providing vital health care services to people in developing countries without reliable electricity, refrigeration and state-of-the-art medical equipment poses a number of challenges. Inspired by pregnancy tests, researchers from Florida Atlantic University, Stanford University, and Baskent University in Turkey, have developed a novel method to store microfluidic devices for CD4 T cell testing in extreme weather conditions for up to six months without refrigeration.

14 Apr 2016

Medical School News and Research

Researchers find way to attack a process that tumor cells use to escape effects of cancer drugs

Royal Society of Medicine, ITN Productions jointly launch new initiative ‘Doctors of the Future’

New research centre to tackle childhood obesity to be launched at University of Sydney’s CPC

Women with epilepsy have likelihood of achieving successful pregnancy just as healthy peers

New study to explore outcomes of pregnancy in Brazilian women with Zika virus

MGH-led study confirms safety of allergy immunotherapy

How will IoT impact healthcare? An interview with David Doherty

Study supports screening for HLA-B*5801 gene variant in Asian, black patients with gout

International panel reclassifies a type of thyroid tumor to reduce cancer overdiagnosis

Investigators find tacrolimus to be very effective in reducing ocular symptoms of GVHD

Removal of Dnmt1 enzyme during OPC differentiation could lead to neurological symptoms

Adolescent obesity linked to elevated risk of cardiovascular mortality in midlife

Scientists identify key pathway that regulates 'switch' between wakefulness and sleep

Slow-wave sleep may promote consolidation of recent memories

Expanding insurance coverage for elective single-embryo transfer could result in ideal pregnancy outcomes

Growth chart of brain networks could spot early signs of attention difficulties in children

VIEKIRAX and EXVIERA achieve high SVR rates in GT1 and GT4 hepatitis C virus infected patients

Improving body clock could protect against metabolic syndrome

M10 peptide could help protect systemic sclerosis patients against fibrotic damage

Researchers develop novel method to store microfluidic devices for CD4 T cell testing

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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