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Black garlic may have anti-cancer and anti-inflammatory properties

The anti-inflammatory and anti-cancer properties of black garlic (BG).

5 Feb 2024

UVA scientists develop new approach to machine learning for identifying heart drug

University of Virginia scientists have developed a new approach to machine learning – a form of artificial intelligence – to identify drugs that help minimize harmful scarring after a heart attack or other injuries.

5 Feb 2024

eLabNext and Promega join forces to accelerate digital transformation in life science labs

eLabNext (an Eppendorf Group Company), the provider of a Digital Lab Platform with lab inventory management system (LIMS), electronic lab notebook (ELN), and artificial intelligence (AI)/machine learning (ML) solutions for life science laboratories, and Promega Corporation (Promega), a global leader in innovative technologies, tools, and technologies for the life science industry, announced a collaboration today to make Promega’s standard operating procedures (SOPs) readily accessible through the eLabNext’s eLabMarketplace.

5 Feb 2024

Xist lncRNA identified as key trigger in female-biased autoimmune diseases

Researchers uncover that the Xist ribonucleoprotein complex, unique to females, is a key driver of sex-biased autoimmunity, offering new insights into autoimmune disorders' higher prevalence in women.

4 Feb 2024

Small-molecule A485 mobilizes white blood cells on demand

New study reveals a small molecule that can selectively mobilize white blood cells, offering potential treatments for diseases with abnormal leukocyte counts.

3 Feb 2024

CAR T cells target senescent cells, improve healthspan in mice

Chimeric antigen receptor (CAR) T cells have transformed the treatment of blood cancers in recent years. And there have been positive signs the "living drugs" can be harnessed against other diseases, like autoimmune disorders.

2 Feb 2024

New vaccine may be potential off-the-shelf treatment for pancreatic, colorectal cancer

A new vaccine shows encouraging early results as a potential off-the-shelf treatment for certain patients with pancreatic or colorectal cancer, according to a study co-led by researchers at Memorial Sloan Kettering Cancer Center (MSK).

2 Feb 2024

Researchers discover mechanism that protects tissue after faulty gene expression

The genetic material, in the form of DNA, contains the information that is crucial for the correct functioning of every human and animal cell.

2 Feb 2024

Proteogenomics reveals new target for beating drug resistance in acute myeloid leukemia

Doctors have nearly a dozen new targeted drugs to treat patients with acute myeloid leukemia, or AML, yet three of four patients still die within five years.

2 Feb 2024

Engrailed-1 protein promotes pancreatic cancer progression and metastasis

Pancreatic cancer is the No. 3 cause of cancer-related deaths in the United States, and only 12% of patients survive five years after being diagnosed.

2 Feb 2024

Unveiling HIV's "latch": New study reveals key to blocking infection

As the HIV virus glides up outside a human cell to dock and possibly inject its deadly cargo of genetic code, there's a spectacularly brief moment in which a tiny piece of its surface snaps open to begin the process of infection.

2 Feb 2024

CRISPR-Cas9 gene-editing tool repairs defective T cells to treat rare hereditary disease

Some hereditary genetic defects cause an exaggerated immune response that can be fatal. Using the CRISPR-Cas9 gene-editing tool, such defects can be corrected, thus normalizing the immune response, as researchers led by Klaus Rajewsky from the Max Delbrück Center now report in "Science Immunology."

2 Feb 2024

New study identifies key role of microRNA-29 in scar-free wound healing

New findings in The American Journal of Pathology, published by Elsevier, report that a class of small RNAs (microRNAs), microRNA-29, can restore normal skin structure rather than producing a wound closure by a connective tissue (scar).

2 Feb 2024

Study reveals the spatial connectivity patterns of mouse hippocampal neurons

A study published in Science on Feb. 1 reported a comprehensive database of single-neuron projectomes consisting of over 10,000 mouse hippocampal neurons, thus revealing the spatial connectivity patterns of mouse hippocampal neurons at the mesoscopic level.

2 Feb 2024

Scientists discover orderly structure hidden within bacterial biofilms

Bacteria are traditionally imagined as single-cell organisms, spread out sparsely over surfaces or suspended in liquids, but in many environments the true bacterial mode of growth is in sticky clusters called biofilms.

2 Feb 2024

Viscoelasticity emerges as key marker for liver cancer in diabetes

For centuries, doctors have used their hands as essential diagnostic tools - exploring joints and palpating abdomens to assess a patient's health.

2 Feb 2024

Researchers find new clue to treating aggressive Wilms tumor subtype

An international team, led by researchers at Nagoya University in Japan, may have determined why the diffuse anaplasia (DA) subtype of Wilms tumor (WT) resists chemotherapy.

2 Feb 2024

Breakthrough gene-editing therapy transforms lives of patients with a hereditary disorder

A group of patients with a hereditary disorder have had their lives transformed by a single treatment of a breakthrough gene-editing therapy, according to the lead researcher.

2 Feb 2024

Yokogawa introduces CellVoyager High-Content Analysis System CQ3000

The CQ3000 will be showcased at SLAS2024 Boston, MA, February 3-7 with live on-booth demonstrations (booth #485)

From Yokogawa Life Science 2 Feb 2024

A promising approach for aging research

In mid-January 2024, the Friedrich Schiller University Jena made an important discovery public: A team of researchers from the universities of Jena and Shenzhen (China), as well as the Jena University Hospital, decoded a molecular mechanism that plays a crucial role in the development of breast cancer.

1 Feb 2024