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IUPUI researcher receives $2.85 million grant to find ways to improve bone strength

A $2.85 million National Institute of Arthritis and Musculoskeletal and Skin Diseases-funded study at IUPUI will advance understanding of how bone cells sense and respond to mechanical force, one of the cues the skeleton relies on to regulate its strength.

21 Jan 2019

Scientists reveal new mechanism that could lead to specific treatment of strokes and seizures

The ideal drug is one that only affects the exact cells and neurons it is designed to treat, without unwanted side effects.

21 Jan 2019

Ural Federal University scientists synthesize a group of multi-purpose fluorophores

A group of scientists from Russia's Ural Federal University, headed by Professor Grigory Zyryanov, synthesized a group of multi-purpose fluorophores.

18 Jan 2019

UIC researchers receive $1.7 million NCI grant to study Southeast Asian fruit

For generations, traditional healers in Southeast Asia have used the mangosteen fruit to treat skin infections, wounds, dysentery and urinary tract infections.

18 Jan 2019

UCLA researchers demonstrate new technique to develop cancer-fighting T cells

A study by UCLA researchers is the first to demonstrate a technique for coaxing pluripotent stem cells -- which can give rise to every cell type in the body and which can be grown indefinitely in the lab -- into becoming mature T cells capable of killing tumor cells.

18 Jan 2019

Scientists discover a dramatic pattern of bone growth in female mice

UCLA and UC San Francisco life scientists have discovered a dramatic pattern of bone growth in female mice -- research that could potentially lead to stronger bone density in women and new treatments for osteoporosis in older women.

18 Jan 2019

Research brings new hope to treating degenerative brain diseases

Alzheimer's disease is the most representative degenerative brain disease, accounting for 60 to 80% of all dementia cases. In search for new mechanism for AD, the research team led by Professor Seong-Woon Yu of Brain and Cognitive Sciences paid attention to the autophagy of microglia, brain immune cells, is suppressed by inflammation.

17 Jan 2019

Breast cancers more likely to metastasize in young women within 10 years of giving birth

A study by researchers at University of Colorado Cancer Center and Oregon Health & Science University published today in the Journal of the American Medical Association Network shows that breast cancers diagnosed in young women within 10 years of giving birth are more likely to metastasize, and thus more likely to cause death, than breast cancers in young women who gave birth less recently or not at all.

17 Jan 2019

Cellular protein that interacts with viruses appears to enable infection process of Zika virus

A cellular protein that interacts with invading viruses appears to help enable the infection process of the Zika virus, according to an international team of researchers who suggest this protein could be a key target in developing new therapies to prevent or treat Zika virus infection.

17 Jan 2019

New project receives €8.65 million from EU and Canada to ease genomic, health data sharing

The European Union and the Canadian government have awarded the international iReceptor Plus consortium, which is composed of more than 20 partners, €8.65 million to promote human immunological data storage, integration and controlled sharing for a wide range of clinical and scientific purposes.

16 Jan 2019

TGF-beta signaling pathway in uterine cells protects against cancer

Two new mouse models of uterine cancer shed light on how this disease - the most common gynecological cancer in the U.S. - happens.

16 Jan 2019

FDA-approved drug hampers cancer metastasis in animal model, shows study

For cancer to spread, it needs a hospitable environment in distant organs. This fertile "soil" can provide a home to circulating malignant cells.

16 Jan 2019

Researchers find how GREB1 gene promotes resistance to prostate cancer treatments

Researchers have discovered how a gene involved in regulating hormone receptors may contribute to drug resistance in some prostate cancer patients.

16 Jan 2019

Scientists identify endogenous activator of sigma-1 receptors in human cells

Cells communicate through complex mechanisms that typically involve receptors and ligands that bind to them. Endogenous ligands, produced by the body, have been identified for the vast majority of cellular receptors, helping explain receptor existence and function. But in the case of sigma-1 receptors, which interact with a diverse array of psychoactive drugs, an endogenous ligand has remained elusive.

14 Jan 2019

Identifying genetic factors that lead to squamous cell carcinoma

Skin cancer is on the rise in the United States. Squamous cell carcinoma, the second most common form of cancer in the U.S., has the highest mortality rate of all non-melanoma skin cancers. In roughly two to five percent of patients, the disease will metastasize and spread throughout the body, making it difficult to treat.

14 Jan 2019

New class of sleeping pill preserves ability to wake in response to danger signals

In a trial of one of the main class of prescription sleeping pills, half the participants slept through a fire alarm as loud as someone vacuuming next to their bed. But a newer alternative preserves the ability to wake in response to danger signals, according to a new research.

11 Jan 2019

Receptor News and Research

IUPUI researcher receives $2.85 million grant to find ways to improve bone strength

Scientists reveal new mechanism that could lead to specific treatment of strokes and seizures

Ural Federal University scientists synthesize a group of multi-purpose fluorophores

UIC researchers receive $1.7 million NCI grant to study Southeast Asian fruit

UCLA researchers demonstrate new technique to develop cancer-fighting T cells

Scientists discover a dramatic pattern of bone growth in female mice

Research brings new hope to treating degenerative brain diseases

Breast cancers more likely to metastasize in young women within 10 years of giving birth

Cellular protein that interacts with viruses appears to enable infection process of Zika virus

New project receives €8.65 million from EU and Canada to ease genomic, health data sharing

TGF-beta signaling pathway in uterine cells protects against cancer

FDA-approved drug hampers cancer metastasis in animal model, shows study

Researchers find how GREB1 gene promotes resistance to prostate cancer treatments

Scientists identify endogenous activator of sigma-1 receptors in human cells

Identifying genetic factors that lead to squamous cell carcinoma

New class of sleeping pill preserves ability to wake in response to danger signals

Study raises hopes for new approaches to treat osteoporosis

Expression of a molecule in blood cells inversely predicts appearance of subclinical atherosclerosis

Neuropeptide Y may hold key to exacerbating severe influenza

Study explains why some drugs work well in ameliorating side effects of chemotherapy

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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