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How can we defeat drug resistance? An interview with Dr Grania Brigden

The O’Neill report is a wide ranging report recognising anti-microbial resistance (AMR) as a global problem with major public health and economic significance.

15 Jun 2016

New electronic sensor can distinguish between dead and living bacteria cells

A new type of electronic sensor that might be used to quickly detect and classify bacteria for medical diagnostics and food safety has passed a key hurdle by distinguishing between dead and living bacteria cells.

15 Jun 2016

Revolutionary technology can prevent spread of hospital-acquired infections

Nano Textile, introduces a revolutionary technology that can transfer any type of fabric to one that kills bacteria.

15 Jun 2016

Liposome nanoencapsulation can increase efficacy of bacteriophages in oral phage therapy

Scientists at the Universitat Autònoma de Barcelona and the Catalan Institute for Nanoscience and Nanotechnology have developed a nanoencapsulation system with a liposome coating in order to increase the efficacy of bacteriophages in oral phage therapy.

14 Jun 2016

EPFL researchers reprogram TAMs to prevent tumor metastasis

One of the major obstacles with treating cancer is that tumors can conscript the body's immune cells and make them work for them. Researchers at EPFL have now found a way to reclaim the corrupted immune cells, turn them into signals for the immune system to attack the tumor, and even prevent metastasis.

14 Jun 2016

Tiny molecular scaffolding could be key to fight against antibiotic resistance

Tiny molecular scaffolding that joins molecules together could be the key to our battle against antibiotic resistance. Research published in Bioorganic & Medicinal Chemistry Letters shows that carbon nanodot scaffolding assembled with small molecules called polyamines can kill some dangerous drug-resistant bacteria, including Acinetobacter baumanii and Klebsiella pneumonia.

14 Jun 2016

New experimental antibiotic can help combat MRSA infections

A new experimental antibiotic developed by a team of scientists at Rutgers University successfully treats the deadly MRSA infection and restores the efficacy of a commonly prescribed antibiotic that has become ineffective against MRSA.

14 Jun 2016

Pediatric diseases and treatment could have greater impact on intestinal microbial diversity

Tracy C. Grikscheit, MD, pediatric surgeon and principal investigator at The Saban Research Institute of Children's Hospital Los Angeles, treats a large number of young patients who require surgery for various intestinal diseases.

14 Jun 2016

T memory cells with naive phenotype can help boost immunity in older adults

Sixty-five is the age when many people retire, kick back and take it easy. And so it often is with the human immune system.

14 Jun 2016

Researchers unravel species-function relationships in gut microbial genomes

Despite recent progress, the organization and ecological properties of the intestinal microbial ecosystem remain under investigated. Using a manually curated metabolic module framework for (meta-)genomic data analysis, Sara Vieira-Silva, Gwen Falony and colleagues from the Jeroen Raes lab studied species-function relationships in gut microbial genomes and microbiomes.

14 Jun 2016

FDA approves Vaxchora for prevention of cholera

The U.S. Food and Drug Administration today approved Vaxchora, a vaccine for the prevention of cholera caused by serogroup O1 in adults 18 through 64 years of age traveling to cholera-affected areas. Vaxchora is the only FDA-approved vaccine for the prevention of cholera.

13 Jun 2016

New vaccine found safe, effective against Toxic Shock Syndrome

Toxic Shock Syndrome (TSS) is a severe circulatory and organ failure caused by bacterial toxins, usually triggered by bacteria from the Staphylococcus group. Researchers from MedUni Vienna's Department of Clinical Pharmacology, in collaboration with the company Biomedizinische Forschungsgesellschaft mbH in Vienna, have now developed the world's first safe and effective vaccine against this disease and successfully tested it in a Phase I trial.

13 Jun 2016

About 30% of iPSCs not safe for clinical use, report multi-institutional researchers

As the promise of using regenerative stem cell therapies draws closer, a consortium of biomedical scientists reports about 30 percent of induced pluripotent stem cells they analyzed from 10 research institutions were genetically unstable and not safe for clinical use.

10 Jun 2016

New method helps speed up bacterial identification

Pinpointing the type of bacteria that are at the root of an infection in clinical samples removed from living tissues, such as blood, urine or joint fluids, to quickly identify the best anti-microbial therapy still poses a formidable challenge.

10 Jun 2016

Tackling Healthcare Challenges in a Changing World: an Interview with Professor Jeremy Nicholson

As individuals and as populations our risks of getting diseases are determined partly genetically and partly from the environment that we live in. An important part of that environment that mediates between the outside world and the inside world of our bodies is the microbiome.

10 Jun 2016

Scientists explore effects of physiological fluid shear on dangerous type of Salmonella

Once inside the human body, infectious microbes like Salmonella face a fluid situation. They live in a watery world, surrounded by liquid continually flowing over and abrading their cell surfaces--a property known as fluid shear.

9 Jun 2016

Far-UVC light can combat deadly scourge of drug-resistant surgical site infections

Scientists from the Center for Radiological Research at Columbia University Medical Center have shown that a narrow wavelength of ultraviolet (UV) light safely killed drug-resistant MRSA bacteria in mice, demonstrating a potentially safe and cost-effective way to reduce surgical site infections, a major public health concern.

9 Jun 2016

Understanding DNA scrunching could help develop novel ways to fight infections

Evidence of DNA "scrunching" may one day lead to a new class of drugs against viruses, according to a research team from the Perelman School of Medicine at the University of Pennsylvania, the Georgia Institute of Technology, and Columbia University.

9 Jun 2016

Research reveals complicated love story between bacterial virulence and antibiotic resistance

It's thought that antibiotic resistance is associated with a fitness cost, meaning that bacteria that develop antibiotic resistance must sacrifice something in order to do so. Because of this, proper use of antibiotics should result in susceptible strains eventually replacing resistant ones.

8 Jun 2016

New drug-capture device can soak up chemotherapy drugs to limit toxicity

Doctors have a powerful arsenal of cancer-fighting chemotherapy drugs to choose from, though a key challenge is to better target these drugs to kill tumors while limiting their potentially harmful side effects.

8 Jun 2016