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New tool may help clinicians provide more personalized treatment strategies following coronary stent procedures

Nearly 1 million people in the United States receive coronary artery stents each year. Nearly all stent patients are expected to take dual antiplatelet therapy (DAPT) using the combination of aspirin and a second antiplatelet medication to prevent the formation of blood clots. Exactly how long patients should receive DAPT has been debatable.

30 Mar 2016

UC Riverside researchers identify immune protein that protects the body from infections

Researchers in the School of Medicine at the University of California, Riverside have identified an immune protein in mice that is quickly triggered in the body following infection and serves to protect the body's tissues. Called "RELMalpha," this protein, whose homologue in humans is called "resistin," is responsible more for protecting the body than attacking the parasite.

30 Mar 2016

Automated sample-to-answer system could make EVD diagnosis easier

An automated "sample-to-answer" system could provide Ebola virus disease (EVD) diagnosis more quickly and easily than the current standard test, according to research published this week in PLOS Medicine.

30 Mar 2016

Higher aortic stiffness associated with reduced white matter volume among young adults

A large, multi-center study led by the UC Davis School of Medicine for the first time has shown that people as young as their 40s have stiffening of the arteries that is associated with subtle structural damage to the brain that is implicated in cognitive decline and Alzheimer's disease later in life.

29 Mar 2016

Network of connections between neurons reveals how brain circuits are organized

Even the simplest networks of neurons in the brain are composed of millions of connections, and examining these vast networks is critical to understanding how the brain works.

29 Mar 2016

High out-of-pocket costs linked to lower use of specialty drugs

"Specialty drugs" have become important treatment options for many serious and chronic diseases, and in some conditions like cancer they represent the only chance for long-term survival.

29 Mar 2016

New approach allows noninvasive identification of tumor mutations in lung cancer patients

Researchers at the Stanford University School of Medicine have devised a way to significantly increase the sensitivity of a technique to identify and sequence DNA from cancer cells circulating in a person's blood.

29 Mar 2016

DTI may predict functional post-deployment outcomes for veterans with MTBI

Diffusion tensor imaging (DTI), a type of MRI, may be able to predict functional post-deployment outcomes for veterans who sustained mild traumatic brain injury (MTBI), or concussion, during combat, according to a new study published in the journal Radiology.

29 Mar 2016

CCN5 protein reverses cardiac fibrosis in heart failure models

CCN5, a matricellular protein, has been found to reverse established cardiac fibrosis in heart failure models, according to a study led by Roger J. Hajjar, MD, Professor of Medicine and Director of the Cardiovascular Research Center at the Icahn School of Medicine at Mount Sinai, and Woo Jin Park, PhD, Professor of Life Sciences at the Gwangju Institute of Science and Technology, South Korea.

29 Mar 2016

Scientists identify two enzymes that appear to play role in metabolism, inflammation

A team led by scientists at The Scripps Research Institute and the Salk Institute for Biological Studies has discovered two enzymes that appear to play a role in metabolism and inflammation—and might someday be targeted with drugs to treat type 2 diabetes and inflammatory disorders.

29 Mar 2016

BIDMC investigators identify precise 5-gene classifier for discriminating early pancreatic cancer

Pancreatic cancer, the fourth leading cause of cancer death in the United States, is often diagnosed at a late stage, when curative treatment is no longer possible. A team led by investigators at Beth Israel Deaconess Medical Center has now identified and validated an accurate 5-gene classifier for discriminating early pancreatic cancer from non-malignant tissue.

28 Mar 2016

MGH study finds that the brains of young marijuana users react differently to social exclusion

A study from Massachusetts General Hospital researchers finds that the brains of young adult marijuana users react differently to social exclusion than do those of non-users. In a report published in the March issue of Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, the team reports that activation of the insula, a region of the brain that is usually active during social rejection, was reduced in young marijuana users when they were being excluded from participation in virtual game of catch.

26 Mar 2016

Wnt secretion inhibitors may reduce renal fibrosis

Renal fibrosis or the scarring of kidneys, following an injury, reduces their function and can cause kidney disease to progressively worsen.

25 Mar 2016

Virus-generated DNA lurking between human genes, show research

Think your DNA is all human? Think again. And a new discovery suggests it's even less human than scientists previously thought.

24 Mar 2016

Simple tool for inserting intrauterine device may offer low-cost option for long-term contraception

A simple tool designed for inserting an intrauterine device may offer women in the developing world a convenient, low-cost option for long-term contraception.

24 Mar 2016

Children with cardiomyopathy may benefit from family-linked treatment

A newly published national study by the Children's Hospital of Michigan and Wayne State University School of Medicine researchers shows that "parental impact and family functioning" become increasingly abnormal when children with cardiomyopathy-related chronic heart disease are more severely ill than children less affected by the disease.

24 Mar 2016

Penn neurologists uncover new genetic cause of Charcot-Marie-Tooth Disease

Charcot-Marie-Tooth Disease (CMT) is a family of inherited disorders of the peripheral nervous system, affecting approximately one in 2,500 Americans. Its most common iteration, CMT1, comes in many forms, most of which have to date been linked to a small set of causative genes.

23 Mar 2016

Mount Sinai Hospital uses M1 LUMI Bead loaded with doxorubicin for liver cancer treatment

An innovative cancer treatment made of luminescent chemotherapy-filled beads injected into tumors through the wrist is now available for patients with inoperable and difficult-to-treat liver cancer.

23 Mar 2016

USC's Keck School of Medicine researcher named recipient of NCI Outstanding Investigator Award

Distinguished Professor Jae Jung, PhD, chair of the Department of Molecular Microbiology & Immunology and the director of the University of Southern California Institute for Emerging Pathogens and Immune Diseases at the Keck School of Medicine of USC, is among this year's recipients of the National Cancer Institute Outstanding Investigator Award.

23 Mar 2016

Whole genome sequencing of chimpanzee parasite reveals clues about human malaria

Understanding the origins of emerging diseases - as well as more established disease agents -- is critical to gauge future human infection risks and find new treatment and prevention approaches. This holds true for malaria, which kills more than 500,000 people a year. Symptoms, including severe anemia, pregnancy-associated malaria, and cerebral malaria, have been linked to the parasite's ability to cause infected red blood cells to bind to the inner lining of blood vessels.

22 Mar 2016

Medical School News and Research

New tool may help clinicians provide more personalized treatment strategies following coronary stent procedures

UC Riverside researchers identify immune protein that protects the body from infections

Automated sample-to-answer system could make EVD diagnosis easier

Higher aortic stiffness associated with reduced white matter volume among young adults

Network of connections between neurons reveals how brain circuits are organized

High out-of-pocket costs linked to lower use of specialty drugs

New approach allows noninvasive identification of tumor mutations in lung cancer patients

DTI may predict functional post-deployment outcomes for veterans with MTBI

CCN5 protein reverses cardiac fibrosis in heart failure models

Scientists identify two enzymes that appear to play role in metabolism, inflammation

BIDMC investigators identify precise 5-gene classifier for discriminating early pancreatic cancer

MGH study finds that the brains of young marijuana users react differently to social exclusion

Wnt secretion inhibitors may reduce renal fibrosis

Virus-generated DNA lurking between human genes, show research

Simple tool for inserting intrauterine device may offer low-cost option for long-term contraception

Children with cardiomyopathy may benefit from family-linked treatment

Penn neurologists uncover new genetic cause of Charcot-Marie-Tooth Disease

Mount Sinai Hospital uses M1 LUMI Bead loaded with doxorubicin for liver cancer treatment

USC's Keck School of Medicine researcher named recipient of NCI Outstanding Investigator Award

Whole genome sequencing of chimpanzee parasite reveals clues about human malaria

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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