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Columbia University Medical Center, NewYork-Presbyterian Hospital present research works at AAN meeting

The following research from Columbia University Medical Center and NewYork-Presbyterian Hospital is being presented at the 65th annual meeting of the American Academy of Neurology, March 16-23, 2013, in San Diego.

18 Mar 2013

Researchers identifiy elusive anti-cancer property of vitamin E

Researchers have identified an elusive anti-cancer property of vitamin E that has long been presumed to exist, but difficult to find. Many animal studies have suggested that vitamin E could prevent cancer, but human clinical trials following up on those findings have not shown the same benefits.

16 Mar 2013

Small percentage of adults who receive rapid HIV treatment following infection might achieve 'functional cure,' French researchers say

"Rapid treatment after HIV infection may be enough to 'functionally cure' about a 10th of those diagnosed early, say researchers in France," who "have been analyzing 14 people who stopped therapy, but have since shown no signs of the virus resurging," BBC News reports (Gallagher, 3/15).

16 Mar 2013

Research shows changes in mouse coat color were the result of nine mutations within a single gene

For deer mice living in the Nebraska Sandhills, color can literally be the difference between life and death. When they first colonized the region, the dark-coated mice stood out starkly against the light-colored, sandy soil, making them easy prey for predators.

15 Mar 2013

Researchers receive AHRF grant to investigate genetic hearing screening program for newborns

Researchers at the Medical College of Wisconsin in Milwaukee, Wisconsin, have received a grant from the American Hearing Research Foundation to conduct a pilot study of genetic hearing screening for newborns at the Children's Hospital of Wisconsin to ensure the test can be performed and results shared with the parents in a timely and meaningful way.

15 Mar 2013

Study: Novel strategy could lead to universal influenza vaccine that can provide long-lasting protection

Seasonal epidemics of influenza result in nearly 36,000 deaths annually in the United States, according to the Centers for Disease Control. Current vaccines against the influenza virus elicit an antibody response specific for proteins on the outside of the virus, specifically the hemagglutinin protein.

15 Mar 2013

Max Planck Florida Institute for Neuroscience gets grant for research into neurological disorders

The Max Planck Florida Institute for Neuroscience, the first and only U.S. extension of the prestigious Max Planck Society, today announced it has received approximately $1,257,500 in grant funding from prestigious national and international organizations to fund research into Parkinson-s, epilepsy and other neurological disorders.

15 Mar 2013

Study identifies genetic cause of developmental delay in Amish individuals in USA

Researchers from the research group in growth factors and cell differentiation at the University of Barcelona (UB) and the IDIBELL and have participated in an international study that has identified the genetic cause of developmental delay observed in Amish individuals in the USA.

15 Mar 2013

VCP gene mutations cause neurological conditions including IBMPFD and ALS

New research, published in Neuron, gives insight into how single mutations in the VCP gene cause a range of neurological conditions including a form of dementia called Inclusion Body Myopathy, Paget's Disease of the Bone and Frontotemporal Dementia (IBMPFD), and the motor neuron disease Amyotrophic Lateral Sclerosis (ALS).

14 Mar 2013

Advanced gene sequencing test helps clinicians treat cancer

The University of Washington and Seattle Cancer Care Alliance (SCCA) partnered to launch UW-OncoPlex - an advanced gene sequencing test to help clinicians treat cancer. The new diagnostic tool is a significant milestone in the development of precision medicine and empowers doctors to predict which treatment therapies will be most effective for an individual patient's cancer.

14 Mar 2013

3-D structure of HNF-4α reveals new pockets that could be targeted with therapeutic drugs

Researchers at Sanford-Burnham Medical Research Institute have determined the complete three-dimensional structure of a protein called HNF-4α.

14 Mar 2013

Study demonstrates relationship between protein HERC2 and human diseases

Researchers from the research group in growth factors and cell differentiation at IDIBELL and the University of Barcelonahave participated in an international study that has identified the genetic cause of developmental delay observed in Amish individuals in the USA.

13 Mar 2013

Immune system B cells play crucial role in defence of pathogens

Immune system B cells play a crucial role in the defence of pathogens; when they detect such an intruder, they produce antibodies that help to combat the enemy.

13 Mar 2013

Researchers determine way to predict and protect against new strains of flu virus

Researchers have determined a way to predict and protect against new strains of the flu virus, in the hope of improving immunity against the disease.

13 Mar 2013

ADP-ribose plays key role in repairing cellular DNA damage

Attaching chains of the small molecule ADP-ribose to proteins is important for a cell's survival and the repair of DNA damage, making this process a promising target for the development of new cancer drugs.

13 Mar 2013

Lack of very long chain fatty acids does not cause blindness in children with Stargardt type 3

Vision scientists long have thought that lack of very long chain fatty acids in photoreceptor cells caused blindness in children with Stargardt type 3 retinal degeneration, an incurable eye disease. But researchers at the University of Utah's John A. Moran Eye Center have shown in a new study that lack of these fatty acids does not cause blindness, meaning that the search for the mechanism that robs sight from children with the disease must start anew.

12 Mar 2013

Researchers identify new mechanism in onset of motor neuron diseases

The British astrophysicist Stephen Hawking is likely to be the world's most famous person living with amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease. ALS is a progressive disease affecting motor neurons, nerve cells that control muscle function, and nearly always leads to death.

11 Mar 2013

Influenza drug: an interview with Dr Jenny McKimm-Breschkin, CSIRO

Influenza or flu for short is caused by a family of viruses, which can be called influenza A or influenza B. Influenza A viruses are found in humans, animals – like swine and horses- and mostly aquatic birds. Influenza B is only found in humans.

11 Mar 2013

Genetic mutation that alters PIEZO1 ion channel in RBCs contributes to familial xerocytosis

A genetic mutation that alters the kinetics of an ion channel in red blood cells has been identified as the cause behind a hereditary anemia, according to a paper published this month in the Proceedings of the National Academy of Sciences by University at Buffalo scientists and colleagues.

11 Mar 2013

Combining mitochondrial inhibitors could improve efficacy of BRAF inhibitors in melanoma

A multi-institutional study has revealed that BRAF-positive metastatic malignant melanomas develop resistance to treatment with drugs targeting the BRAF/MEK growth pathway through a major change in metabolism.

11 Mar 2013

Mutation News and Research

Columbia University Medical Center, NewYork-Presbyterian Hospital present research works at AAN meeting

Researchers identifiy elusive anti-cancer property of vitamin E

Small percentage of adults who receive rapid HIV treatment following infection might achieve 'functional cure,' French researchers say

Research shows changes in mouse coat color were the result of nine mutations within a single gene

Researchers receive AHRF grant to investigate genetic hearing screening program for newborns

Study: Novel strategy could lead to universal influenza vaccine that can provide long-lasting protection

Max Planck Florida Institute for Neuroscience gets grant for research into neurological disorders

Study identifies genetic cause of developmental delay in Amish individuals in USA

VCP gene mutations cause neurological conditions including IBMPFD and ALS

Advanced gene sequencing test helps clinicians treat cancer

3-D structure of HNF-4α reveals new pockets that could be targeted with therapeutic drugs

Study demonstrates relationship between protein HERC2 and human diseases

Immune system B cells play crucial role in defence of pathogens

Researchers determine way to predict and protect against new strains of flu virus

ADP-ribose plays key role in repairing cellular DNA damage

Lack of very long chain fatty acids does not cause blindness in children with Stargardt type 3

Researchers identify new mechanism in onset of motor neuron diseases

Influenza drug: an interview with Dr Jenny McKimm-Breschkin, CSIRO

Genetic mutation that alters PIEZO1 ion channel in RBCs contributes to familial xerocytosis

Combining mitochondrial inhibitors could improve efficacy of BRAF inhibitors in melanoma

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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