Immune Response News and Research

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Green tea consumption increases number of 'regulatory T cells', prevents autoimmune disease

One of the beneficial compounds found in green tea has a powerful ability to increase the number of "regulatory T cells" that play a key role in immune function and suppression of autoimmune disease, according to new research in the Linus Pauling Institute at Oregon State University.

3 Jun 2011

Positive interim results from Fraunhofer USA CMB's HAC1 influenza vaccine Phase 1 trial

Fraunhofer USA Center for Molecular Biotechnology, a not-for-profit, Delaware-based organization focused on developing a proprietary plant-based protein production platform and its applications in vaccine and therapeutic fields, today announced positive interim results from the first human trial of plant-produced H1N1 influenza vaccine that began on September 13, 2010.

2 Jun 2011

Scientists develop carbohydrate-based vaccine against C. difficile infection

There is now a promising vaccine candidate for combating the pathogen which causes one of the most common and dangerous hospital infections. An international team of scientists from the Max Planck Institute of Colloids and Interfaces in Potsdam has developed a vaccine based on a carbohydrate against the Clostridium difficile bacterium, which is known to cause serious gastrointestinal diseases mainly in hospitals.

31 May 2011

Specific influenza immunization strategies for RA patients may be required for future flu pandemics

A Brazilian hospital-based study assessed responses to flu vaccines in 340 RA patients in regular follow-up compared to 234 healthy patients.

26 May 2011

Diabetics have higher risk of contracting tuberculosis

People with diabetes have a three to five times higher risk of contracting tuberculosis (TB) than non-diabetics, according to researchers at The University of Texas Health Science Center at Houston.

25 May 2011

Positive interim results from new bladder cancer therapy trial

Clinical trials for a new bladder cancer therapy show promising interim results. Lead researcher Alvaro Morales says that the breakthrough using the drug Urocidin follows thirty years of his research in this important area.

25 May 2011

Accelerator announces Series A financing of Oncofactor

Accelerator Corporation, a privately held, venture-capital-backed biotechnology investment and development company, announced today the Series A financing of Oncofactor Corporation. This is the twelfth company backed by Accelerator and its first investment based on internal intellectual property developed at Accelerator.

24 May 2011

Study offers hope for reducing incidence of AIDS with potential preventive vaccine

The HIV epidemic is the largest in the world and represents one of the most serious public health problems, according to data from the World Health Organization. Only 30% of the more than 10 million patients in need have the access to the antiretroviral treatment.

24 May 2011

Probiotic bacterial protein could offer new oral therapeutic option for inflammatory bowel disorders

A protein isolated from beneficial bacteria found in yogurt and dairy products could offer a new, oral therapeutic option for inflammatory bowel disorders, suggests a study led by Vanderbilt University Medical Center researcher Fang Yan, M.D., Ph.D.

24 May 2011

H. pylori infection could play a role in Parkinson's disease development

The stomach bacteria responsible for ulcers could also play a role in the development of Parkinson's disease according to research presented today at the 111th General Meeting of the American Society for Microbiology.

23 May 2011

New technique offers successful bone marrow, organ transplant for patients with autoimmune diseases

University of Minnesota Medical School researchers have discovered a method to quickly and exponentially grow regulatory T-cells - also known as "suppressor cells." The new process enables replication of the cells by tens of millions in several weeks, a dramatic increase over previous duplication methods. Historically, regulatory T-cells have been difficult to replicate.

19 May 2011

Children exposed to maternal smoking in utero have increased DNA methylation in AXL gene

Children whose mothers or grandmothers smoked during pregnancy are at increased risk of asthma in childhood, but the underlying causes of this are not well understood. Now a new study indicates changes in a process called DNA methylation that occurs before birth may be a root cause.

19 May 2011

Serpin-2 molecule may be a perfect target for preventing mosquito's immunity

Mosquitoes are becoming more resistant to current pesticides. That's troubling to Kansas State University biologist Kristin Michel, as it means malaria and other mosquito-borne diseases will continue spreading. A recent grant from the National Institutes of Health may change all that.

18 May 2011

New A+PSA assay more accurately detects prostate cancer

A new test for prostate cancer that measures levels of prostate specific antigen (PSA) as well as six specific antibodies found in the blood of men with the disease was more sensitive and more specific than the conventional PSA test used today, according to a study by researchers at UCLA's Jonsson Comprehensive Cancer Center.

17 May 2011

New biomarker can predict breast cancer recurrence

Researchers from Virginia Commonwealth University Massey Cancer Center have discovered a new biomarker related to the body's immune system that can predict a breast cancer patients' risk of cancer recurrence.

17 May 2011

Novel topically-applied molecular microbicide protects women against HIV infection

Using a technique that silences genes promoting infection, researchers have developed a novel, topically-applied molecular microbicide capable of preventing HIV transmission.

17 May 2011

Super-resolution microscopy technique reveals how and why cell's defenses fail against plague

Researchers at Sandia National Laboratories have developed a super-resolution microscopy technique that is answering long-held questions about exactly how and why a cell's defenses fail against some invaders, such as plague, while successfully fending off others like E.coli.

17 May 2011

Hendra virus vaccine to be released soon

According to CSIRO’s early success with testing, the Hendra virus vaccine for horses could be available as early as next year. Hendra virus affects horses and is contracted through contact with flying foxes.

16 May 2011

AIDS spread prevention by vaccine and anti HIV drugs

A latest vaccine against HIV/AIDS has shown to be effective in monkeys and has protected macaques the most widespread primate genus, against the monkey equivalent of HIV, Simian immunodeficiency virus (SIV). This could provide a fresh approach to an HIV vaccine, a study suggests. US researchers say the vaccine offered protection to 13 of 24 Rhesus macaques treated in the experiment. In 12 of the monkeys, the vaccine was still effective 12 months later.

15 May 2011

ZIOPHARM submits IND with FDA for Ad-RTS-IL-12 Phase I study in cancer

ZIOPHARM Oncology, Inc., a drug development company employing small molecule and synthetic biology approaches to cancer therapy, today announced that it has submitted an Investigational New Drug (IND) application to the U.S. Food & Drug Administration (FDA) to begin clinical study of Ad-RTS-IL-12, a novel DNA-based therapeutic candidate.

13 May 2011

Immune Response News and Research

Green tea consumption increases number of 'regulatory T cells', prevents autoimmune disease

Positive interim results from Fraunhofer USA CMB's HAC1 influenza vaccine Phase 1 trial

Scientists develop carbohydrate-based vaccine against C. difficile infection

Specific influenza immunization strategies for RA patients may be required for future flu pandemics

Diabetics have higher risk of contracting tuberculosis

Positive interim results from new bladder cancer therapy trial

Accelerator announces Series A financing of Oncofactor

Study offers hope for reducing incidence of AIDS with potential preventive vaccine

Probiotic bacterial protein could offer new oral therapeutic option for inflammatory bowel disorders

H. pylori infection could play a role in Parkinson's disease development

New technique offers successful bone marrow, organ transplant for patients with autoimmune diseases

Children exposed to maternal smoking in utero have increased DNA methylation in AXL gene

Serpin-2 molecule may be a perfect target for preventing mosquito's immunity

New A+PSA assay more accurately detects prostate cancer

New biomarker can predict breast cancer recurrence

Novel topically-applied molecular microbicide protects women against HIV infection

Super-resolution microscopy technique reveals how and why cell's defenses fail against plague

Hendra virus vaccine to be released soon

AIDS spread prevention by vaccine and anti HIV drugs

ZIOPHARM submits IND with FDA for Ad-RTS-IL-12 Phase I study in cancer

Understanding the DNA Damage Response in Innate Immunity eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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