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Report describes clinical characteristics and outcomes of children hospitalized with COVID-19

While most children infected with the novel coronavirus have mild symptoms, a subset requires hospitalization and a small number require intensive care.

20 May 2020

Nori Health offers conversational coach for people with Crohn's or Colitis during Covid-19

Covid-19 forced the most vulnerable in our society to go into self-isolation, such as the 600.000 people living in the UK with Inflammatory Bowel Disease of which Crohn’s and Colitis are most common.

20 May 2020

Immunotherapy, steroids restore heart function in children with COVID-related multi-system inflammatory syndrome

Treatment with antibodies purified from donated blood - immune globulin therapy - and steroids restored heart function in the majority of children with COVID-related multi-system inflammatory syndrome, according to new research published yesterday in Circulation, the flagship journal of the American Heart Association.

19 May 2020

Understanding why pancreatic ductal adenocarcinoma is so aggressive

Pancreatic ductal adenocarcinoma (PDA) is a deadly cancer, killing patients within a year. CSHL Professor Christopher Vakoc and his former postdoc Timothy Somerville discovered how pancreatic cells lose their identity, acquire a deadly new identity, and recruit nearby cells to help them grow, promote inflammation, and invade nearby tissues.

19 May 2020

Do parasites protect against SARS-CoV-2?

The world has rarely seen such a readily transmissible infection as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) over the last century. Within five months, the virus has created a Tsunami of COVID-19 positive cases, comprising almost 4.88 million people and causing 322,000 deaths.

19 May 2020

Sleep apnea may increase the risk of severe COVID-19, say researchers

An analysis conducted by researchers at the University of Turku and Turku University Hospital in Finland has suggested that obstructive sleep apnea (OSA) may be a risk factor for severe coronavirus disease 2019 (COVID-2019).

19 May 2020

Phase IIB clinical trial initiated for treating hepatitis B-associated liver cancer

The first patients have been dosed in a multi-regional Phase IIB randomized, placebo-controlled clinical trial for the treatment of hepatitis B-associated liver cancer.

19 May 2020

Steroids and immunotherapy improve outcomes in children with COVID-related multi-system inflammatory syndrome

19 May 2020

Study highlights need to focus on medications that address clot formation

Earlier this week, the BBC reported that one-third of COVID-19 patients developed dangerous blood clots.

19 May 2020

Gene variants can increase risk of schizophrenia, shows study

Variants in a gene of the human immune system cause men and women to have different vulnerabilities to the autoimmune diseases lupus and Sjögren's syndrome, according to findings published in the journal Nature.

19 May 2020

Cord blood can improve social communication skills in autistic children

In a recent study, Duke researchers tested whether a single infusion of a unit of a child's own or donor cord blood could improve social communication skills in children between the ages of 2-7 diagnosed with autism spectrum disorder.

19 May 2020

Common cytokine profile in ARDS, severe COVID-19 and sepsis

Many lives have been lost to the severe pneumonic disease COVID-19 caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), during the ongoing pandemic. The reason for the critical lung injury that results in a fatal outcome in a significant minority of patients has been supposed to be the dramatic oversecretion of pro-inflammatory cytokines and chemokines triggered by the virus.

19 May 2020

New animal model for COVID-19

As the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to ravage the world, scientists are frantically searching for a vaccine or new drug that will effectively counter the lethal effects of the virus that leads to COVID-19 disease.

19 May 2020

Study shows how cancer protein changes may accelerate tumorigenesis and metastasis

Understanding the genetic mutations and protein changes that take place in the progression of cancer is key to its treatment. Mutations in the gene TP53 and concomitant mutant p53 proteins in cancer cells have become notorious over the course of multiple studies of several different types of cancers.

18 May 2020

Tocilizumab improves survival in COVID-19 patients with ARDS

The current COVID-19 pandemic caused by the SARS-CoV-2 (severe acute respiratory syndrome coronavirus-2), has already nearly 4.8 million confirmed cases and more than 318,000 deaths.

18 May 2020

Atrial fibrillation risk not linked to the amount of body fat, study shows

In a recently published study, researchers from Aarhus University document that the risk of atrial fibrillation is not linked to the amount of body fat, but instead to large muscle mass, or more precisely, a high fat-free weight.

18 May 2020

Potential new treatment approach to fatal COVID-19

Researchers from the University of Colorado Anschutz Medical Campus and Pathways Bioscience in the United States have found that activating a transcription factor involved in oxidative stress regulation, antiviral activity, and inflammation may serve as a new treatment approach to coronavirus disease 2019 (COVID-19).

18 May 2020