Inflammation News and Research

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Kawasaki disease outbreak in children with COVID-19

The ongoing COVID-19 pandemic has marched its way to almost all parts of the world, with hundreds of thousands of deaths and over 4.5 million cases as of May 15, 2020. One saving grace has been the apparent sparing of children, though the mortality in older people is quite high.

17 May 2020

New and unexplored angle in the binding of SARS-CoV-2 to host cells

Researchers in the Netherlands, Cuba, and Italy have made important discoveries about the carbohydrate-mediated binding of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein to host cell lectin receptors and host lung microbiota.

17 May 2020

COVID-19’s adverse impact on the cardiovascular system

COVID-19 can cause serious cardiovascular complications including heart failure, heart attacks and blood clots that can lead to strokes, emergency medicine doctors report in a new scientific paper.

15 May 2020

Boehringer Ingelheim partners with CDR-Life to develop antibody fragment-based therapeutics for geographic atrophy

Boehringer Ingelheim and CDR-Life today announced they have entered into a collaboration and licensing agreement to research and develop antibody fragment-based therapeutics for geographic atrophy (GA).

From Boehringer Ingelheim International GmbH 15 May 2020

New treatment discovered to reduce swelling after brain and spinal cord injuries

Scientists have discovered a new treatment to dramatically reduce swelling after brain and spinal cord injuries, offering hope to 75 million victims worldwide each year.

15 May 2020

Antiviral agent accelerates virus clearance in cases of COVID-19

A team of researchers from have found an antiviral therapy that seems to be an effective treatment for patients with moderate coronavirus disease 2019 (COVID-19).

15 May 2020

Inflammatory cells arise from local memory cells for advanced multiple sclerosis

In the brains of people that suffer from long-term multiple sclerosis (MS), inflammatory cells are not entering the brain via the bloodstream anymore.

14 May 2020

A promising treatment for chronic inflammatory liver disease

Primary sclerosing cholangitis (PSC) is a rare, chronic, inflammatory disease of the bile ducts and is difficult to treat.

14 May 2020

Variations in genome’s 'dark matter' region can make patients susceptible to inflammatory diseases

A study led by researchers at the Babraham Institute in collaboration with the Wellcome Sanger Institute has uncovered how variations in a non-protein coding 'dark matter' region of the genome could make patients susceptible to complex autoimmune and allergic diseases such as inflammatory bowel disease.

14 May 2020

Scientists describe new mechanism of cellular locomotion

Whilst the whole world is in lockdown during the current Corona crisis, certain cells within our bodies are still travelling long-distance: while this happens when you develop pneumonia, any ordinary cut on your finger will also trigger white blood cells--aka leukocytes--to instantly move out of your blood vessels into the site of inflammation.

14 May 2020

Low albumin levels could predict poor outcome in COVID-19

A Spanish study has revealed that COVID-19 patients who have a low level of albumin have a poorer outcome compared to those with normal levels of blood albumin. The study titled, “Low albumin levels are associated with poorer outcomes in a case series of COVID-19 patients in Spain: a retrospective cohort study,” was released prior to peer-review on the open-access preprint server site Medrxiv*.

13 May 2020

UCI Health to initiate clinical trial of a drug to treat critically ill COVID-19 patients

UCI Health will initiate a clinical study of a drug to treat critically ill COVID-19 patients who face a high mortality rate because of acute inflammation that fills their lungs with fluid, a grave condition that even mechanical ventilation cannot improve.

13 May 2020

Placentas of pregnant women with COVID-19 showed abnormalities

A study conducted by researchers at Northwestern University, Chicago, has found that the placentas of pregnant women who were infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) showed abnormalities, compared with those of uninfected women.

13 May 2020

Research identifies a disease trigger for pancreatitis

One factor contributing to the development of pancreatitis lies in mutations within a cell membrane ion channel that is characterized by its specific permeability for calcium ions.

13 May 2020

Experts review symptoms, diagnosis, and current treatment of COVID-19

The ongoing economic and social impact of the pandemic is staggering, but despite a daily flood of news on the disease, few laypeople know that paradoxically, COVID-19 mostly kills through an overreaction of the immune system, whose function is precisely to fight infections.

13 May 2020

Diabetes type 3c is an early manifestation of pancreatic cancer, shows study

As biomedical sciences incorporate increasingly sophisticated methodologies and technologies, our understanding of diseases improves.

13 May 2020

Study explores whether senicapoc drug can mitigate lung damage in COVID-19 patients

Scientists around the globe are working to identify approved and investigational drugs that can be repurposed to treat COVID-19.

13 May 2020

New study to evaluate drug combination treatment for uveitis

Two in 10,000 people are at risk of serious sight loss from a form of eye inflammation known as uveitis. A new clinical research study, led by the University of Bristol and University Hospitals Bristol and Weston NHS Foundation Trust (UHBW), will evaluate a drug combination treatment for the eye disease thanks to funding of £2.5 million by the National Institute for Health Research (NIHR).

13 May 2020

Researchers launch clinical trial to test the efficacy of antidepressant against COVID-19

An antidepressant medication is being tested as a potential treatment for COVID-19 after University of Virginia School of Medicine researchers determined it may prevent dangerous overreactions by the immune system.

13 May 2020

Research examines molecules derived from ticks as potential COVID-19 treatment option

UK-based biotechnology firm ILC Therapeutics is working alongside the University of Oxford to examine the use of Evasins – molecules derived from ticks – as a potential COVID-19 treatment option for patients whose lungs are badly damaged by the virus and face a critical juncture in recovery.

13 May 2020

Inflammation News and Research

Kawasaki disease outbreak in children with COVID-19

New and unexplored angle in the binding of SARS-CoV-2 to host cells

COVID-19’s adverse impact on the cardiovascular system

Boehringer Ingelheim partners with CDR-Life to develop antibody fragment-based therapeutics for geographic atrophy

New treatment discovered to reduce swelling after brain and spinal cord injuries

Antiviral agent accelerates virus clearance in cases of COVID-19

Inflammatory cells arise from local memory cells for advanced multiple sclerosis

A promising treatment for chronic inflammatory liver disease

Variations in genome’s 'dark matter' region can make patients susceptible to inflammatory diseases

Scientists describe new mechanism of cellular locomotion

Low albumin levels could predict poor outcome in COVID-19

UCI Health to initiate clinical trial of a drug to treat critically ill COVID-19 patients

Placentas of pregnant women with COVID-19 showed abnormalities

Research identifies a disease trigger for pancreatitis

Experts review symptoms, diagnosis, and current treatment of COVID-19

Diabetes type 3c is an early manifestation of pancreatic cancer, shows study

Study explores whether senicapoc drug can mitigate lung damage in COVID-19 patients

New study to evaluate drug combination treatment for uveitis

Researchers launch clinical trial to test the efficacy of antidepressant against COVID-19

Research examines molecules derived from ticks as potential COVID-19 treatment option

Industry Focus eBook - Forensics & toxicology (2nd edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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