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Scientists discover 'small molecule' substance that blocks cholesterol formation in the brain

A needle-in-the-haystack search through nearly 390,000 chemical compounds had led scientists to a substance that can sneak through the protective barrier surrounding the brain with effects promising for new drugs for Parkinson's and Huntington's disease. They report on the substance, which blocks formation of cholesterol in the brain, in the journal, ACS Chemical Biology.

21 Apr 2011

RCSI conducts study to examine psychiatric disorders in people with epilepsy

Researchers from the Royal College of Surgeons in Ireland (RCSI) and Beaumont Hospital, Dublin, have conducted the first study of its kind to examine in detail, the basis of psychiatric disorders which occur in people with epilepsy.

20 Apr 2011

Scientists detect several biomarkers to screen active drugs for Batten disease

Goethe University and Harvard Medical School start screening for active ingredients for the treatment of Batten disease

20 Apr 2011

Anti-depressants spur creation and survival of new brain cells after brain injury

Anti-depressants may help spur the creation and survival of new brain cells after brain injury, according to a study by neurosurgeons at the University of Rochester Medical Center.

19 Apr 2011

Novel lifestyle program may slow loss of brain cells due to aging and also grow new cells

In March, more than 80 residents at Emeritus at Ocoee, an assisted living and memory care community in Central Florida, began a new and highly promising research-based Brain Health Lifestyle Program which was designed to not only slow the loss of brain cells due to aging, but also grow new cells.

18 Apr 2011

Intellectual disability may have genetic origin, but is not hereditary

Mutations in a group of genes associated with brain activity frequently cause intellectual disability, according to a study led by scientists affiliated with the University of Montreal and the research centre at the Centre hospitalier universitaire Sainte-Justine. Intellectual disability is a severe handicap that affects between one and two percent of children worldwide. It can often be attributed to genetic causes, but the specific genes involved were mostly unknown.

18 Apr 2011

Astrocytes regulate circadian system that controls normal sleep patterns

The circadian system that controls normal sleep patterns is regulated by a group of glial brain cells called astrocytes, according to a study published online on April 14th in Current Biology, a Cell Press publication. Neuroscientists from Tufts University School of Medicine found that disruption of astrocyte function in fruit flies ( Drosophila) led to altered daily rhythms, an indication that these star-shaped glial cells contribute to the control of circadian behavior.

15 Apr 2011

Scientists identify filter neurons that can reduce 'brain clutter'

Until now, it has been assumed that people with diseases like ADHD, Tourette syndrome, obsessive compulsive disorder and schizophrenia - all of whom characteristically report symptoms of "brain clutter" - may suffer from anomalies in the brain's prefrontal cortex.

15 Apr 2011

Brain damage starts decade earlier in Alzheimer’s patients

A new study published in the journal Neurology has shown that the brains of people diagnosed with Alzheimer's disease start shrinking up to a decade before symptoms appear. Researchers from Rush University Medical Center in Chicago and Massachusetts General Hospital in Boston did brain imaging tests on older adults with no signs of memory loss.

15 Apr 2011

Scientists discover how anti-depressants make new brain cells

For the first time in a human model, scientists have discovered how anti-depressants make new brain cells. This means that researchers can now develop better and more efficient drugs to combat depression.

12 Apr 2011

Rockefeller University professor earns recognition in developmental psychobiology

Weill Cornell Medical College and the Columbia University College of Physicians and Surgeons have announced that The Mortimer D. Sackler, M.D. Prize for Distinguished Achievement in Developmental Psychobiology has been awarded to The Rockefeller University's Dr. Fernando Nottebohm for his seminal work in songbirds that has led to the discovery of neuronal replacement.

12 Apr 2011

Air pollution on freeways may lead to brain damage: Study

Earlier research has shown that air pollution from cars and trucks on Southern California freeways – that contains soot, pavement dust and other toxic substances - can cause respiratory disease, heart attacks, cancer and premature death. Now a new study has shown that exposure to pollution particles roughly one-thousandth the width of a human hair may lead to brain damage in mice, including signs associated with memory loss and Alzheimer’s disease. The study comes from University of Southern California and is published in the journal Environmental Health Perspectives.

10 Apr 2011

CoMeD urges UN to ban mercury use in pharmaceuticals

While the United Nations actively questions the use of a vaccine preservative that contains the known neurotoxin mercury, the Coalition for Mercury-Free Drugs, a Maryland-based, non-profit organization, is urging the UN to ban it.

7 Apr 2011

Johns Hopkins scientists identify autism gene linked to severity of social interaction deficits

With the help of two sets of brothers with autism, Johns Hopkins scientists have identified a gene associated with autism that appears to be linked very specifically to the severity of social interaction deficits.

7 Apr 2011

Study explores physical effect of freeway pollution on brain cells

If mice commuted, their brains might find it progressively harder to navigate the maze of Los Angeles freeways.

7 Apr 2011

MRIs can help predict MCI individuals at greatest risk for developing Alzheimer's disease

Using MRI, researchers may be able to predict which adults with mild cognitive impairment are more likely to progress to Alzheimer's disease, according to the results of a study published online and in the June issue of Radiology.

6 Apr 2011

New insight into Parkinson's disease

As Parkinson's Awareness Month gets underway, a Canadian-led international study is providing important new insight into Parkinson's disease and paving the way for new avenues for clinical trials.

5 Apr 2011

Study: Antidepressants can thicken arteries and lead to heart disease

Antidepressant use has been linked to thicker arteries, possibly contributing to the risk of heart disease and stroke, in a study of twin veterans. The data is being presented Tuesday, April 5 at the American College of Cardiology meeting in New Orleans.

4 Apr 2011

Navy sonar experts develop new medical device for stroke detection

A medical device developed by retired U.S. Navy sonar experts, using submarine technology, is a new paradigm for the detection, diagnosis and monitoring of stroke, says a team of interventional radiologists at the Society of Interventional Radiology's 36th Annual Scientific Meeting in Chicago, Ill.

30 Mar 2011

Protein aggregation plays a significant role in cancer

Protein aggregation, generally associated with Alzheimer's and mad cow disease, turns out to play a significant role in cancer. In a paper published in Nature Chemical Biology, Frederic Rousseau and Joost Schymkowitz of VIB, K.U.Leuven and Vrije Universiteit Brussel describe that certain mutations of p53, an important tumor suppressor, cause the protein to misfold in a way that the proteins start to aggregate.

29 Mar 2011