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UC researchers find stem cell vaccine to enhance immune responses against tumors in animal models

Researchers at the University of Cincinnati have found that a cancer stem cell vaccine, engineered to express a pro-inflammatory protein called interleukin-15 (IL-15) and its receptor (IL-15Ralpha), caused T cell production in animal models and enhanced immune responses against tumors.

10 May 2017

New findings pinpoint key feature of rare childhood disease that could help fast-track diagnosis

Australian scientists have shown, for the first time, that a family of untethered proteins builds up in the cells of children with a rare and serious genetic condition, known as mevalonate kinase deficiency (MKD).

10 May 2017

Scientists develop easy-to-use diagnostic test that could rapidly detect flu

The threat of a major flu pandemic is a perennial concern. Now scientists have developed a fast and easy-to-use point-of-care diagnostic test that could one day help doctors and hospitals head off the rapid spread of the flu.

10 May 2017

Researchers identify brain cells that drive fruit flies’ food choices based on nutrition needs

Using fruit flies, Johns Hopkins researchers say they have identified a specific and very small set of brain cells -- dubbed dopamine wedge neurons -- responsible for driving the insects' food preferences toward what they need, rather than what they like.

10 May 2017

Swiss researchers discover potential way to design new antibiotics

Two Swiss research teams from the University of Bern and the ETH Zurich have developed a new method to shed light onto a mostly unknown process of bacterial protein production. Their results could be used for the design of new antibiotics.

10 May 2017

Scientists study cell’s reaction to Salmonella by visualizing protein chains at near-molecular level

With drug resistance being on the rise worldwide, bacterial infections pose one of the greatest global threats to human health. By deciphering the host-pathogen interaction on a molecular level, researchers hope to pave the way for new therapies.

10 May 2017

Researchers uncover structure of embryo-protecting protein

Revelations about a protein expressed in fetal cells could provide novel insights into its function and future immunosuppressive therapies.

10 May 2017

Natural compound in grape seed extract could increase strength, life of composite-resin fillings

A natural compound found in grape seed extract could be used to strengthen dentin -- the tissue beneath a tooth's enamel -- and increase the life of resin fillings, according to new research at the University of Illinois at Chicago College of Dentistry.

10 May 2017

Scientists aim to revolutionize asthma treatment by replacing inhalers with new drug

A common treatment for asthma, which is the most prevalent chronic childhood disease, requires use of an inhaler. But a big problem with inhalers, used to deliver steroids and other drugs in an aerosol form, is that children often don't operate them properly.

10 May 2017

Researchers discover that microRNA can prevent excessive intestinal inflammation

An international team of researchers has discovered that a microRNA produced by certain white blood cells can prevent excessive inflammation in the intestine.

9 May 2017

Study findings could help identify treatments for balding and hair graying

Researchers at the UT Southwestern Medical Center have discovered the cells that are directly responsible for hair growth and the mechanism that causes gray hair. The study results could help in identifying feasible treatments for balding and hair graying.

9 May 2017

Novel nanoscale molecular slingshot could ‘shoot’ and deliver drugs at precise disease locations

An international team of researchers from the University of Rome Tor Vergata and the University of Montreal has reported, in a paper published this week in Nature Communications, the design and synthesis of a nanoscale molecular slingshot made of DNA that is 20,000 times smaller than a human hair.

9 May 2017

UT Southwestern researchers uncover mechanism linked to balding and hair graying

UT Southwestern Medical Center researchers have identified the cells that directly give rise to hair as well as the mechanism that causes hair to turn gray - findings that could one day help identify possible treatments for balding and hair graying.

9 May 2017

Study reveals role of good-guy protein in initiating and maintaining cancer

Under normal conditions, the CHD4 protein is one of the good guys: it stops cells from transcribing faulty DNA, thereby eliminating potential mutation. But in colon cancer and perhaps other kinds of cancer as well, it appears that this protein becomes a kind of double agent, working for the enemy.

9 May 2017

Study findings shed new light on evolution and interaction of ancient proteins

How did protein interactions arise and how have they developed? In a new study, researchers have looked at two proteins which began co-evolving between 400 and 600 million years ago.

9 May 2017

Researchers develop fast algorithm that provides new insights into protein evolution

Understanding evolution is one of the cornerstones of biology - evolution is, in fact, the sole explanation for life's diversity on our planet.

9 May 2017

Study findings suggest how progranulin deficiency causes frontotemporal dementia

In a recent study in Human Molecular Genetics, researchers from VIB and KU Leuven led by prof. Philip Van Damme, reveal a novel function for progranulin in lysosomes: it acts as chaperone of the lysosomal protease cathepsin D. The results were obtained in collaboration with Prof. Paul Saftig from the University of Kiel.

8 May 2017

Choice of fat causes distinct epigenetic changes in human adipose tissue, study shows

Previous research has demonstrated that saturated fat is more fattening and less muscle building than polyunsaturated fats. A new study shows that the choice of fat causes epigenetic changes which in turn could contribute to differences in fat storage.

8 May 2017

Study uncovers potential new therapeutic targets for HCV infections

An international study led by researchers at Monash University' Biomedicine Discovery Institute (BDI) has shone light on the way the Hepatitis C Virus (HCV) hijacks the communication systems in the host cells it infects, uncovering potential new therapeutic targets for the disease.

8 May 2017

Machine learning algorithm can help predict progression of age-related macular degeneration

Scientists have demonstrated that a machine learning algorithm, using images of patients' retinas obtained over time, can predict the critical moment when early or intermediate age-related macular degeneration (AMD) will progress into severe AMD.

8 May 2017

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G Protein News and Research

UC researchers find stem cell vaccine to enhance immune responses against tumors in animal models

New findings pinpoint key feature of rare childhood disease that could help fast-track diagnosis

Scientists develop easy-to-use diagnostic test that could rapidly detect flu

Researchers identify brain cells that drive fruit flies’ food choices based on nutrition needs

Swiss researchers discover potential way to design new antibiotics

Scientists study cell’s reaction to Salmonella by visualizing protein chains at near-molecular level

Researchers uncover structure of embryo-protecting protein

Natural compound in grape seed extract could increase strength, life of composite-resin fillings

Scientists aim to revolutionize asthma treatment by replacing inhalers with new drug

Researchers discover that microRNA can prevent excessive intestinal inflammation

Study findings could help identify treatments for balding and hair graying

Novel nanoscale molecular slingshot could ‘shoot’ and deliver drugs at precise disease locations

UT Southwestern researchers uncover mechanism linked to balding and hair graying

Study reveals role of good-guy protein in initiating and maintaining cancer

Study findings shed new light on evolution and interaction of ancient proteins

Researchers develop fast algorithm that provides new insights into protein evolution

Study findings suggest how progranulin deficiency causes frontotemporal dementia

Choice of fat causes distinct epigenetic changes in human adipose tissue, study shows

Study uncovers potential new therapeutic targets for HCV infections

Machine learning algorithm can help predict progression of age-related macular degeneration

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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