Genetic Engineering News and Research

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More people and dwindling fish stocks create supply gap in omega-3 fatty acids

Everyone knows that eating fish is good for you, in part because of the healthy omega-3 fatty acids that it contains.

9 Feb 2020

CD19 CAR NK cell therapy clinical trial shows encouraging results for hematologic cancers

According to results from a Phase I/IIa trial at The University of Texas MD Anderson Cancer Center, treatment with cord blood-derived chimeric antigen receptor natural killer (NK)-cell therapy targeting CD19 resulted in clinical responses in a majority of patients with relapsed or refractory non-Hodgkin's lymphoma and chronic lymphocytic leukemia, with no major toxicities observed.

6 Feb 2020

Scientists identify gene as potential therapeutic target for dementia in people with Parkinson's

Dementia is one of the most debilitating consequences of Parkinson's disease, a progressive neurological condition characterized by tremors, stiffness, slow movement and impaired balance.

6 Feb 2020

Study may suggest new therapeutic approaches to control immune responses

Researchers have provided new insight on the role of cyclic AMP (cAMP) in regulating the immune response.

5 Feb 2020

Researchers develop an emergency stop switch for CAR T-cell therapies

Immunotherapy, unlike chemotherapy and radiotherapy, arms the body's immune system to attack cancer cells. In recent years, it has proven to be remarkably successful at treating leukemia, lymphoma and other liquid cancers, or cancers present in body fluids.

4 Feb 2020

UTHSC researchers receive $1.98 million grant for novel approach to studying diabetes

A team of researchers in the University of Tennessee Health Science Center's College of Medicine has been awarded a $1.98 million grant from the National Institute of Diabetes and Digestive and Kidney Disease, a division of the National Institutes of Health, for a novel approach to studying diabetes.

3 Feb 2020

Scientists describe genetic program behind primordial lung progenitors

For the first time, researchers describe the genetic program behind primordial lung progenitors--embryonic cells that give rise to all the cells that form the lining of the respiratory system after birth.

31 Jan 2020

New discovery could enable scientists to fine-tune activity of cancer-killing immune cells

A discovery by University of North Carolina Lineberger Comprehensive Cancer Center researchers could allow scientists to fine-tune genetically engineered immune cells to heighten their killing power against tumors or to decrease their activity level in the case of severe side effects.

31 Jan 2020

Researchers create new brain cancer model using genetically engineered pluripotent stem cells

Using genetically engineered human pluripotent stem cells, University of California San Diego School of Medicine researchers created a new type of cancer model to study in vivo how glioblastoma, the most common and aggressive form of brain cancer, develops and changes over time.

29 Jan 2020

UMD entomologists recognized by AAAS with 2019 Newcomb Cleveland Prize

The American Association for the Advancement of Science awarded its 2019 Newcomb Cleveland Prize to University of Maryland entomologists Raymond St. Leger, Brian Lovett and their seven West African collaborators.

24 Jan 2020

First glioblastoma patient treated with genetically modified poliovirus at UH

University Hospitals Seidman Cancer Center treated its first patient in a new clinical trial to validate the groundbreaking effects of the poliovirus on glioblastoma, a deadly Grade IV cancer of the brain.

24 Jan 2020

T. gondii parasite employs a sophisticated manipulation to suppress host's immune response

Toxoplasma gondii is best known as the parasite that may lurk in a cat's litter box. Nearly a third of the world's population is believed to live with a chronic Toxoplasma infection.

24 Jan 2020

Researchers solve long-standing mystery linked to contraction of heart cells

We've all felt the effects of an adrenaline rush. Faced with danger, real or perceived, the heart beats faster, breathing quickens and muscles tighten as the body prepares to fight a threat or flee from it.

23 Jan 2020

Synthego adopts good manufacturing practices for highest-quality genome engineering for clinical applications

Synthego, the genome engineering company, today announced it has adopted Good Manufacturing Practice standards to provide academic and industry partners with high-quality reagents for use in clinical research and development.

From Synthego Corporation 23 Jan 2020

MIT spin-out partners with Cambridge Consultants to co-develop the first Flowfect system

MIT spin-out company Kytopen has engaged Cambridge Consultants to co-develop the first Flowfect system.

22 Jan 2020

Potential Parkinson's treatment effectively targets a specific group of brain cells

Scientists have discovered that a non-invasive technique which could one day be used to treat Parkinson's disease, can successfully target a highly specific group of brain cells which play a key role in development of the condition.

22 Jan 2020

Novel drug inhibits liver damage, obesity and glucose intolerance in mice fed with high-fat diet

Mice given a new drug targeting a key gene involved in lipid and glucose metabolism could tolerate a high-fat diet regimen (composed of 60% fat from lard) without developing significant liver damage, becoming obese, or disrupting their body's glucose balance.

20 Jan 2020

Fish oil supplements could benefit testicular function in healthy men finds study

A large Danish study has shown that fish oil supplements taken by healthy men of the reproductive age could help improve their testicular function as is evidenced by their semen quality and reproductive hormone levels. The study led by researcher Tina Kodd Jensen, titled, “Associations of Fish Oil Supplement Use With Testicular Function in Young Men,” was published this week in the latest issue of the JAMA.

19 Jan 2020

Finding has major ramifications for ongoing drug development against MLL-rearranged leukemia

A massive research effort over more than a quarter century has tried to make personalized blood stem cells for use in treating leukemias, among many other uses.

17 Jan 2020

Genetically engineered mosquitoes halt Dengue spread

A new study published in the journal PLOS Pathogens in January 2020 reports the development of mosquitoes that have been genetically modified to resist infection by several types of the dengue virus. This is the first time ever that all types of the virus have been targeted by the engineering of the mosquito DNA. Covering all virus types is essential to achieve proper disease control.

16 Jan 2020

Genetic Engineering News and Research

More people and dwindling fish stocks create supply gap in omega-3 fatty acids

CD19 CAR NK cell therapy clinical trial shows encouraging results for hematologic cancers

Scientists identify gene as potential therapeutic target for dementia in people with Parkinson's

Study may suggest new therapeutic approaches to control immune responses

Researchers develop an emergency stop switch for CAR T-cell therapies

UTHSC researchers receive $1.98 million grant for novel approach to studying diabetes

Scientists describe genetic program behind primordial lung progenitors

New discovery could enable scientists to fine-tune activity of cancer-killing immune cells

Researchers create new brain cancer model using genetically engineered pluripotent stem cells

UMD entomologists recognized by AAAS with 2019 Newcomb Cleveland Prize

First glioblastoma patient treated with genetically modified poliovirus at UH

T. gondii parasite employs a sophisticated manipulation to suppress host's immune response

Researchers solve long-standing mystery linked to contraction of heart cells

Synthego adopts good manufacturing practices for highest-quality genome engineering for clinical applications

MIT spin-out partners with Cambridge Consultants to co-develop the first Flowfect system

Potential Parkinson's treatment effectively targets a specific group of brain cells

Novel drug inhibits liver damage, obesity and glucose intolerance in mice fed with high-fat diet

Fish oil supplements could benefit testicular function in healthy men finds study

Finding has major ramifications for ongoing drug development against MLL-rearranged leukemia

Genetically engineered mosquitoes halt Dengue spread

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