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Measles wipes out other immune memories

Thanks to misinformation and anti-vaccination campaigns in some pockets, United States and several nations of Europe have seen a massive outbreak of vaccine preventable measles infection over the recent years.

3 Nov 2019

Femtogenix announces new data on ADCs containing reduced potency payloads in solid tumor models

Femtogenix Ltd, a UK biotechnology company developing the next generation of DNA-interactive Antibody Drug Conjugate payloads, today announced data demonstrating the potent efficacy and favorable toxicity profile of a reduced potency analogue from its Pyridinobenzodiazepine ADC payload platform in solid tumor models.

From Pheon Therapeutics 29 Oct 2019

Femtogenix announces efficacy, toxicity data of new DNA-binding ADC payload molecules

Femtogenix Ltd, a UK biotechnology company developing the next generation of DNA-interactive Antibody Drug Conjugate (ADC) payloads, today announced data verifying the favorable toxicity profile and potent efficacy of its Pyridinobenzodiazepine (PDD) ADC payload platform in tumor cell models.

14 Oct 2019

Scientists uncover details of antibody response to Ebola virus vaccine

In the recurring, deadly Ebola outbreaks in parts of Africa, today's health workers now have at least some tools to fight the disease: vaccines. Vaccines against Ebola have been administered to over 100,000 people to date, but they are barely out of the experimental stage.

10 Oct 2019

New study shows response to HIV vaccine in 6 weeks

A US study on DNA-based and protein HIV vaccines has shown that an antibody and cellular immune response occurs within six weeks.

2 Oct 2019

New study shows response to HIV vaccine in 6 weeks

A new study using DNA-based and protein HIV vaccines in various combinations shows that antibody and cellular immune response occurs within 6 weeks from the date of vaccination, and the combination must be administered together for the most rapid protection. This will enable more large-scale testing of the vaccine for effectiveness. About 40 million people today have HIV infections, and 1.2 million deaths a year are related to this infection.

1 Oct 2019

Advancing towards 100% effective herpes vaccine

Genital herpes, caused by the herpes simplex virus 2 (HSV-2) is a very common sexually transmitted infection (STI). It affects 14% of Americans aged 15-49 years. There is no herpes vaccine at present. Many failed attempts at vaccine production have centered around HSV proteins.

23 Sep 2019

Researchers identify an unexpected genetic plasticity in bat-borne influenza viruses

Bat-borne influenza viruses enter host cells by utilizing surface exposed MHC-II molecules of various species, including humans.

18 Sep 2019

Mutant live attenuated Ebola virus elicits protective immunity in monkeys

Inoculation with an Ebola virus that has mutations in a protein called VP35 does not cause disease and elicits protection in monkeys, researchers show September 17 in the journal Cell Reports.

17 Sep 2019

CAR T-cell therapy may be viable treatment option for heart disease

CAR T-cell therapy, a rapidly emerging form of immunotherapy using patients' own cells to treat certain types of cancers, may be a viable treatment option for another life-threatening condition: heart disease.

12 Sep 2019

Measles back in UK three years after elimination

The United Kingdom was declared to be free of measles infection three years back in 2016 by the World Health Organization (WHO). In a recent development, due to the increasing number of cases of measles among unvaccinated children, the WHO has declared that UK can no longer be called measles-free.

20 Aug 2019

Study reveals Lassa virus' soft spot

As this year's Lassa fever outbreak in Nigeria is finally ebbing, the total tally came to more than 600 infected people, one-quarter of them dead. Thousands more die each year, uncounted in rural villages throughout West Africa.

9 Aug 2019

Ultrasensitive method for direct detection of circulating tumor cells in blood

Tumor cells circulating in blood are markers for the early detection and prognosis of cancer. However, detection of these cells is challenging because of their scarcity.

8 Aug 2019

Researchers explain how 'viral' agents of neurological diseases ended up in our DNA

What if the missing ‘environmental’ factor in some of our deadliest neurological diseases were really written in our genome?

11 Jul 2019

Engineered stem cells offer new treatment for metastatic bone cancer

Engineered stem cells could help treat metastatic cancers in bone without killing normal surrounding bone.

9 Jul 2019

UVA launches Fibrosis Initiative to fight the growing cause of death

Fibrosis is often associated with many of the fatal diseases that pervade our globe, riddling organs with stiff tissue that diminishes their flexibility and leads to their failure.

21 Jun 2019

Scientists develop universal FACS-based approach to heterogenous cell sorting, propelling organoid research

Researchers have developed three novel FACS protocols that can be used to isolate neural progenitors, astrocytes, and neurons from infected cerebral organoids.

19 Jun 2019

Researchers find more effective way to treat drug-resistant cancers

Researchers at SMU's Center for Drug Discovery, Design and Delivery have succeeded in lab testing the use of chemotherapy with a specific protein inhibitor so that the chemotherapeutic is better absorbed by drug-resistant cancer cells without harming healthy cells.

10 Jun 2019

Study describes new viral molecular evasion mechanism used by cytomegalovirus

A study published in the journal PLOS Pathogens describes a new viral molecular evasion mechanism used by cytomegalovirus to interfere in the immune response of the infected host.

30 Apr 2019

Stem cells in hair follicles have potential to regenerate myelin sheath that coats neurons

A subset of the stem cells in hair follicles have the potential to regenerate the coating that insulates neurons in mice, reports Thomas Hornyak of the VA Maryland Health Care System and the University of Maryland School of Medicine and colleagues, in a new study published 24th April in PLOS Genetics.

25 Apr 2019