Hepatitis B Virus News and Research

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Silymarin does not provide greater benefit for patients with chronic HCV infection

Use of the botanical product silymarin, an extract of milk thistle that is commonly used by some patients with chronic liver disease, did not provide greater benefit than placebo for patients with treatment-resistant chronic hepatitis C virus (HCV) infection, according to a study in the July 18 issue of JAMA.

18 Jul 2012

Hepatitis C treatment may be helped by vitamin B12 supplements

Adding vitamin B12 to standard hepatitis C virus (HCV) treatment significantly boosts the body’s ability to keep the virus at bay, indicates a pilot study published online in the journal Gut.

18 Jul 2012

Johnson & Johnson second quarter sales decrease 0.7% to $16.5B

Johnson & Johnson today announced sales of $16.5 billion for the second quarter of 2012, a decrease of 0.7% as compared to the second quarter of 2011. Operational results increased 3.5% and the negative impact of currency was 4.2%.

17 Jul 2012

Helper T cells may be frontline warriors when battling hepatitis A infection

Helper cells traditionally thought to only assist killer white blood cells may be the frontline warriors when battling hepatitis A infection. These are the findings from a Nationwide Children's Hospital study appearing in a recent issue of the Journal of Experimental Medicine.

17 Jul 2012

Liver failure, cancer and mortality in cirrhotic patients coinfected with HIV/AIDS and HCV predicted by liver stiffness

Researchers from Spain established that liver stiffness, measured by transient elastography (TE), is an independent predictor of liver failure, hepatocellular carcinoma (HCC), and mortality in cirrhotic patients coinfected with the human immunodeficiency virus (HIV) or acquired immune deficiency syndrome (AIDS), and hepatitis C virus (HCV).

10 Jul 2012

Hepatitis C levels higher among males and African Americans

Epidemiologists have determined that levels of hepatitis C virus (HCV) found among injection drug users (IDUs) were higher in individuals who are male or African American even after differences in other factors were considered.

10 Jul 2012

Alcoholic hepatitis linked to hepatitis C risk

Hepatitis C virus is more common in patients with alcoholic hepatitis than the general population, but infections may be going undetected, US data show.

9 Jul 2012

UN food standards body agrees on new regulations to protect health of consumers across the world

The UN food standards body has agreed on new regulations - including the maximum level of melamine in liquid milk formula for babies - to protect the health of consumers across the world. Other measures adopted include new food safety standards on seafood, melons, dried figs and food labelling.

5 Jul 2012

DKK1 boosts liver cancer diagnostic options

Measurement of the protein Dickkopf-1 in serum could be used to diagnose hepatocellular carcinoma, especially early disease, Chinese researchers report.

2 Jul 2012

Medivir, Bristol-Myers Squibb to initiate TMC435 and daclatasvir phase II combination study in HCV

Medivir AB, the research-based pharmaceutical company focused on the development of high-value treatments for infectious diseases, announces that a phase II combination study with the investigational compound TMC435 and Bristol-Myers Squibb's investigational compound daclatasvir will start in July.

29 Jun 2012

HCV suppression reduces liver damage

Profound suppression of the hepatitis C virus reduces long-term hepatic inflammation and fibrosis even in patients who do not achieve a sustained virologic response, research demonstrates.

19 Jun 2012

Hepatitis C more prevalent among homeless adults in downtown Los Angeles

Recent government studies show that hepatitis C, which can destroy the liver and necessitate a liver transplant, now kills more American adults than AIDS, and new UCLA research shows just how prevalent the disease is among homeless adults in downtown Los Angeles.

12 Jun 2012

Arrowhead initiates final IND-enabling steps for ARC-520 to treat HBV

Arrowhead Research Corporation, a targeted therapeutics company, today announced that its hepatitis B virus (HBV) program has completed all internal preclinical requirements and has named a clinical candidate.

7 Jun 2012

Ancient hepatitis B may hold clues to viral evolution, spread

The evolution of the hepatitis B virus and its possible migration have become clearer with the sequencing of the oldest sample of the virus, isolated from a mummified 16th-century Korean child, say scientists.

6 Jun 2012

Foreign-born populations in the U.S. are at increased risk for chronic HBV

The prevalence of chronic hepatitis B virus (HBV) infection in the U.S. may be as high as 2.2 million cases according to a new study now available in Hepatology, a journal published by Wiley-Blackwell on behalf of the American Association for the Study of Liver Diseases.

1 Jun 2012

Scientists discover SL9266 'switch' in the Hepatitis C virus

Scientists have discovered a 'switch' in the Hepatitis C virus which could be used as a target for new kinds of drug treatment.

1 Jun 2012

Genetic analysis on Korean mummy reveals unique HBV genotype C2 sequence

The discovery of a mummified Korean child with relatively preserved organs enabled an Israeli-South Korean scientific team to conduct a genetic analysis on a liver biopsy which revealed a unique hepatitis B virus (HBV) genotype C2 sequence common in Southeast Asia.

30 May 2012

Nature Genetics publishes results from whole genome-wide study of recurrent HBV integration in HCC

The Asian Cancer Research Group (ACRG)—an independent, not-for-profit company established by Eli Lilly and Company, Merck (known as MSD outside the United States and Canada) and Pfizer Inc.—in collaboration with BGI—the world's largest genomics organization—today announced the publication of results from a whole genome-wide study of recurrent hepatitis B virus (HBV) integration in hepatocellular carcinoma (HCC) in Nature Genetics.

30 May 2012

New research reveals effective treatments for gastrointestinal conditions

New research being presented at Digestive Disease Week- (DDW) reveals effective treatments for a number of gastrointestinal conditions, which are often chronic and costly.

22 May 2012

New directions and challenges in viral hepatitis care and research

The editors of Gastroenterology, the official journal of the American Gastroenterological Association (AGA) Institute, are pleased to announce the publication of this year's highly anticipated special 13th issue. Published each May, the 13th issue is devoted to a particular gastroenterological topic of broad interest; this year's topic is viral hepatitis.

16 May 2012