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Gene-edited immune cells show promise against advanced GI cancers

Researchers at the University of Minnesota have completed a first-in-human clinical trial testing a CRISPR/Cas9 gene-editing technique to help the immune system fight advanced gastrointestinal (GI) cancers.

3 May 2025

Medicaid unwinding may have put opioid recovery care at risk

The massive national effort to return the Medicaid enrollment process to its pre-pandemic rules starting in April 2023 may have disrupted the care of people receiving treatment for opioid addiction, a new University of Michigan study suggests.

3 May 2025

Medicaid enrollment drops linked to disrupted care for young people

Children and young adults with depression, schizophrenia, ADHD, asthma and epilepsy can get great relief from medications to control their symptoms, helping them stay in school or work and prepare for their futures.

3 May 2025

MRI technique reveals the heart's functional age

Scientists at the University of East Anglia (UEA) have developed a revolutionary new way of uncovering the 'true age' of your heart using MRI.

2 May 2025

Study: One in four early cardiogenic shock patients experience worse outcomes

In one of the largest studies of early cardiogenic shock (CS) patients, where blood flow is still functioning to vital organs, researchers demonstrated that 26% experienced worse outcomes, including care escalation, CS deterioration, or in-hospital mortality.

2 May 2025

Sequential cancer therapies improve survival in rare lymphomas

Study data reveal how a specific sequence of cancer therapies can improve outcomes for patients with hard-to-treat lymphomas.

2 May 2025

Gut immune cells linked to worsening rheumatoid arthritis

After spending years tracing the origin and migration pattern of an unusual type of immune cell in mice, researchers have shown in a new study how activity of "good" microbes in the gut is linked to rheumatoid arthritis and, potentially, other autoimmune diseases.

2 May 2025

High certainty and large rewards boost motivation in formerly depressed individuals

New research shows that individuals who have recovered from depression are generally less willing to exert effort to pursue potential rewards compared to those who have never experienced depression, unless the rewards are large and highly likely.

1 May 2025

California’s primary care shortage persists despite ambitious moves to close gap

Sumana Reddy, a primary care physician, struggles on thin financial margins to run Acacia Family Medical Group, the small independent practice she founded 27 years ago in Salinas, a predominantly Latino city in an agricultural valley often called "the salad bowl of the world."

1 May 2025

New protein target offers hope for treating high blood pressure and aortic aneurysms

Oxidative stress can occur when our cells are exposed to harmful molecules called "reactive oxygen species" over time. These reactive oxygen species can damage cells and are found in important disease states, such as high blood pressure and aortic aneurysms.

30 Apr 2025

Noninvasive brain modulation using sound waves shows promise for depression and anxiety

Patients suffering from depression, anxiety and trauma-related disorders experienced significant relief from their symptoms after a new treatment that uses sound waves to modulate deep brain activity, according to new research from Dell Medical School at The University of Texas at Austin.

28 Apr 2025

New blood test can improve heart disease risk prediction

For almost 60 years, measuring cholesterol levels in the blood has been the best way to identify individuals at high risk of cardiovascular disease.

28 Apr 2025

Pre and post-surgical immunotherapy improves survival in head and neck cancer patients

Patients with locally advanced head and neck cancer who received the immune checkpoint inhibitor pembrolizumab before, during and after standard-of-care surgery had longer event-free survival without the cancer coming back and higher rates of substantial tumor shrinkage prior to surgery, according to the first interim analysis of a randomized, open-label phase 3 clinical trial led by investigators from Dana-Farber Brigham Cancer Center and Washington University School of Medicine in St. Louis.

27 Apr 2025

Dana-Farber experts present innovative cancer studies at the 2025 AACR Annual Meeting

Numerous studies conducted by researchers at Dana-Farber Cancer Institute report progress for cancers including head and neck cancer, metastatic breast cancer and lung cancer.

27 Apr 2025

New Medicare changes ease cost burden for cancer drugs

Even for patients covered by Medicare, annual out-of-pocket costs for lifesaving cancer treatments taken in pill form have often exceeded $10,000-until recently.

25 Apr 2025

New era of medicine emerges through structural control of nanotherapeutics

Historically, the vast majority of pharmaceutical drugs have been meticulously designed down to the atomic level.

25 Apr 2025

Serum hsa_circ_101555 as a promising biomarker for hepatocellular carcinoma

Hepatocellular carcinoma (HCC) represents the most prevalent malignancy in Egypt and globally. However, non-invasive diagnostic/prognostic biomarkers for early detection of HCC are still lacking. Circular RNAs (circRNAs) are one of the promising biomarkers.

24 Apr 2025

lncRNAs shape the tumor microenvironment and drive cancer development

The tumor microenvironment (TME) is a complex and dynamic network consisting of tumor cells, immune cells, stromal cells, extracellular matrix (ECM), cytokines, and growth factors, all interacting to influence tumorigenesis, progression, and metastasis.

24 Apr 2025

Powerful imaging technique developed to study bone marrow in mouse models

Indiana University School of Medicine scientists have developed a powerful new imaging technique to study bone marrow in mouse models.

24 Apr 2025

Monoclonal antibody can effectively reverse bleeding complications linked to ticagrelor

An investigational monoclonal antibody called bentracimab can safely and effectively reverse potentially catastrophic bleeding complications linked to ticagrelor, a common drug used to treat patients with acute coronary syndromes, prior heart attack, stroke, and coronary artery disease.

24 Apr 2025