RNA Sequencing News and Research

RSS

Eating grapes may reduce the risk of fatty liver disease

In a recent study published in the journal Foods, eating grapes can extend life expectancy by five years and reduce non-alcoholic fatty liver disease risk in mice fed high-fat diets.

17 Aug 2022

New technique keeps the cells alive during RNA extraction

RNA sequencing allows scientists to study the expression of genes in a cell. Since messenger RNA (mRNA) is generated from a DNA gene, that information can be used to identify the original gene sequence and thus measure the activity of thousands of genes (i.e. the transcriptome) in these cells.

17 Aug 2022

Genetic variant associated with Alzheimer's disease plays a role in protecting against glaucoma

New research led by scientists at Mass Eye and Ear and Brigham and Women's Hospital, member hospitals of Mass General Brigham, reveals the role that a genetic variant associated with Alzheimer's disease, APOE4, plays in protecting against glaucoma.

16 Aug 2022

KAUST bioscientists develop new method to study the bone marrow microenvironment in greater detail

Deep molecular analysis of the bone marrow microenvironment reveals that the cells regulating blood stem cell maintenance are more diverse than expected and have features likely to be conserved between species.

16 Aug 2022

Researchers develop Cluster-Wells to facilitate the study of circulating tumor cells

Cancer spreads via circulating tumor cells (CTCs) that travel through the blood to other organs, and they are nearly impossible to track. Now, researchers at the Georgia Institute of Technology have found a detection method that could revolutionize cancer treatment by showing how cancers metastasize and what stage they are. This could lead to earlier and more targeted treatment, beginning with a simple blood test.

16 Aug 2022

PET imaging could help measure the pharmacodynamic effects of using STING-activating drugs

Stimulator of interferon genes, or STING, helps regulate immune activation. Thus, drugs that activate STING are being tested as a form of cancer immunotherapy and for treating certain infections.

11 Aug 2022

Aberrant levels of three microRNAs may impair healing in venous ulcers, study shows

The study, which includes the first resource detailing the role of microRNAs in the wound-repair process, shows that aberrant levels of a trio of microRNAs may impair healing in venous ulcers.

9 Aug 2022

Study reveals the intertumoral heterogeneity of METex14 skipping positive NSCLCs

A study presented today at the IASLC World Conference on Lung Cancer 2022 in Vienna disclosed the clinical-relevant intertumoral heterogeneity of non-small cell lung cancer (NSCLC) driven by MET exon 14 skipping.

8 Aug 2022

Gut microbiota-derived metabolites offer protection against SARS-CoV-2

A new study investigated how the gut microbiome confers immunity to mammalian hosts against SARS-CoV-2 intranasal infection by generating short-chain fatty acids.

5 Aug 2022

Baboons at Amboseli offer clues to the costs of the hybridization, study says

New genetic analyses of wild baboons in southern Kenya reveals that most of them carry traces of hybridization in their DNA. As a result of interbreeding, about a third of their genetic makeup consists of genes from another, closely-related species.

5 Aug 2022

Heart failure arises from mutations in distinct genes, study finds

Heart failure is a common and devastating disorder for which there is no cure. Many cardiomyopathies - conditions that make it difficult for the heart to pump blood such as dilated cardiomyopathy (DCM) and arrhythmogenic cardiomyopathy (ACM) - can lead to heart failure, but treatments for patients with heart failure do not take these distinct conditions into account.

5 Aug 2022

Study provides new insight into the cellular and molecular biology of human heart failure

Studying heart samples from patients with cardiomyopathies, as well as from controls without heart disease, researchers have provided new insights into the cellular and molecular biology of human heart failure – a highly fatal condition that affects 23 million people worldwide.

5 Aug 2022

Discovery could prevent insulin resistance and have significant benefits for people with type 2 diabetes

In a potential game changer for patients with type 2 diabetes, a team of researchers at the Diabetes, Obesity, and Metabolism Institute (DOMI) at the Icahn School of Medicine at Mount Sinai has identified a therapeutic target for the preservation and regeneration of beta cells (β cells) - cells in the pancreas that produce and distribute insulin.

4 Aug 2022

scRNA-seq of SARS-CoV-2 infected lung organoids finds NFKB Inhibitor Alpha increased in infected cells

Researchers develop a genetically modified airway organoid system, which overcomes challenges related to natural variations in ACE2 levels

4 Aug 2022

Less efficient replication of ancestral SARS-CoV-2 in primary nasal epithelium of children

A new study revealed that the replication of the ancestral strain of SARS-CoV-2 is less efficient in nasal epithelial cells (NECs) of children.

3 Aug 2022

Study reveals how barrier cells that line the intestines send messages to patrolling T cells

Cells in the gut send secret messages to the immune system. Thanks to new research from La Jolla Institute for Immunology (LJI) scientists, we can finally get a look at what they're saying.

29 Jul 2022

Researchers discover cell signaling pathway responsible for the development of esophageal cancers

Of the roughly 20,000 people in the U.S. diagnosed with esophageal cancer this year, just 4,000 are likely to still be alive in 2027.

28 Jul 2022

Study identifies risks in the use of CRISPR therapeutics

The researchers caution: "The CRISPR genome editing method is very effective, but not always safe. Sometimes cleaved chromosomes do not recover and genomic stability is compromised - which in the long run might promote cancer."

25 Jul 2022

Using genome editing to expand the possibilities of entomological research

Genome sequencing, where scientists use laboratory methods to determine a specific organism's genetic makeup, is becoming a common practice in insect research.

22 Jul 2022

NIH grant awarded to Marshall researcher for studying genetic mechanisms of cocaine addiction

Price E. Dickson, Ph.D., an assistant professor of biomedical sciences at the Marshall University Joan C. Edwards School of Medicine, has received a $407,000 grant from the National Institutes of Health to study the genetic and genomic mechanisms driving the relationship between social reward and cocaine addiction.

22 Jul 2022

RNA Sequencing News and Research

Eating grapes may reduce the risk of fatty liver disease

New technique keeps the cells alive during RNA extraction

Genetic variant associated with Alzheimer's disease plays a role in protecting against glaucoma

KAUST bioscientists develop new method to study the bone marrow microenvironment in greater detail

Researchers develop Cluster-Wells to facilitate the study of circulating tumor cells

PET imaging could help measure the pharmacodynamic effects of using STING-activating drugs

Aberrant levels of three microRNAs may impair healing in venous ulcers, study shows

Study reveals the intertumoral heterogeneity of METex14 skipping positive NSCLCs

Gut microbiota-derived metabolites offer protection against SARS-CoV-2

Baboons at Amboseli offer clues to the costs of the hybridization, study says

Heart failure arises from mutations in distinct genes, study finds

Study provides new insight into the cellular and molecular biology of human heart failure

Discovery could prevent insulin resistance and have significant benefits for people with type 2 diabetes

scRNA-seq of SARS-CoV-2 infected lung organoids finds NFKB Inhibitor Alpha increased in infected cells

Less efficient replication of ancestral SARS-CoV-2 in primary nasal epithelium of children

Study reveals how barrier cells that line the intestines send messages to patrolling T cells

Researchers discover cell signaling pathway responsible for the development of esophageal cancers

Study identifies risks in the use of CRISPR therapeutics

Using genome editing to expand the possibilities of entomological research

NIH grant awarded to Marshall researcher for studying genetic mechanisms of cocaine addiction

Sequencing & Genomics: Elevating Science and Healthcare eBook

Latest eBooks

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Driving innovation in Korean drug development

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

Applications Engineer