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Study confirms that pets can harbor SARS-CoV-2 infection

A new study looks at how dogs and cats within households are susceptible to COVID-19 infection from humans, and whether they act as reservoir species.

16 Feb 2022

Research identifies differences between Omicron lineages BA.1 and BA.2

Researchers recently identified another Omicron lineage, called BA.2, that is more contagious than BA.1, the Omicron lineage that sparked the winter surge of coronavirus cases in January 2022.

16 Feb 2022

Impact of Omicron on COVID-19 prevalence among unvaccinated and vaccinated in Omicron-dominated countries

Scientists have recently explored the impact of the omicron variant of SARS-CoV-2 on the prevalence of COVID-19 in vaccinated and unvaccinated individuals.

16 Feb 2022

Study explores how the electrostatic charge of the SARS-CoV-2 spike protein has changed over time

In a new study, researchers examined the effect of electrostatic changes on the ability of the SARS-CoV-2 Omicron variant to escape immunity.

16 Feb 2022

Omicron RBD-ACE2 binding found to be stronger than wild type SARS-CoV-2 strain

Researchers recently investigated the effect of SARS-CoV-2 Omicron variant mutations on the binding of the receptor-binding domain and angiotensin-converting enzyme-2 to study the overall binding profile of the RBD-ACE2 system.

16 Feb 2022

COVID-19 vaccine boosters shown to confer protection against the SARS-CoV-2 Omicron variant

In a new study, researchers investigated whether a COVID-19 vaccine booster dose is effective against the SARS-CoV-2 Omicron variant.

16 Feb 2022

Research suggests SARS-CoV-2 viral accessory proteins may play significant role in viral evolution

Researchers investigate SARS-CoV-2 mutations present across the whole genome of different SARS-CoV-2 variants.

15 Feb 2022

Neutralizing antibody levels to different SARS-CoV-2 epitopes fluctuate over time

Researchers study antibodies against various SARS-CoV-2 epitopes that may be responsible for neutralizing activities in recovered COVID-19 patients.

15 Feb 2022

Antiviral activity assessment of remdesivir against 10 current and former SARS-CoV-2 variant clinical isolates

A new study published demonstrated the in vitro potencies of RDV and GS-441524 through PRA, and nucleoprotein ELISA against SARS-CoV-2 and other VOC/VOIs isolates with specific substitutions in Nsp12.

15 Feb 2022

Novel glycation patterns help understand Omicron immune escape

A new study explores changes in the sugar structure of the SARS-CoV-2 Omicron variant, which may shed light on its immunologic escape and transmissibility characteristics.

15 Feb 2022

First survey on Omicron BA.2 in France

In a recent study posted to the medRxiv* preprint server, researchers described the emergence of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) 21L/BA.2 Omicron variant in south-eastern France.

14 Feb 2022

Structural protein vimentin facilitates SARS-CoV-2 entry into endothelial cells

Researchers suggest that extracellular vimentin may act as a coreceptor to allow for SARS-CoV-2 entry into cells.

14 Feb 2022

Study analyzes antigenic properties of SARS-CoV-2 Omicron sublineages

A new study elucidated the antigenic properties of the sublineages of the severe acute respiratory syndrome coronavirus-2 Omicron variant.

14 Feb 2022

Study describes a β-CoV spike protein target for protective antibodies that may facilitate pan-β-CoV vaccine development

In a recent study published in Science Translational Medicine, researchers characterized a human antibody targeting betacoronaviruses (β-CoVs).

14 Feb 2022

An alternative strategy targeting furin disrupts SARS-CoV-2 infection cycle

A new study was based on the hypothesis that competitively inhibiting cellular furin and selectively targeting SARS-CoV-2 in the infected viral-producing cells is critical for therapeutic specificity.

14 Feb 2022

How a third booster BNT162b2 dose impacts anti-spike antibody levels

A new study aimed to investigate the mechanism by which the third booster BNT162b2 dose impacts anti-S levels.

14 Feb 2022

mRNA-1273 and mRNA-1273.529 Omicron-specific boosters highly effective in mouse model

In a study posted to the bioRxiv* preprint server, a team of researchers from the United States evaluated the protective effect of the preclinical version of the current Moderna Omicron-targeted mRNA-1273.529 vaccine against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) B.1.1.529 Omicron infection in mice.

14 Feb 2022

Study provides evidence for spike protein-independent attenuation of SARS-CoV-2 Omicron variant

A new study provided the structural basis for a robust interaction between the receptor-binding domain of the SARS-CoV-2 Omicron spike protein and mouse ACE2.

13 Feb 2022

Performance of SARS-CoV-2 antibodies improves only after previous infection, not vaccination

New research to be presented at this year's European Congress of Clinical Microbiology & Infectious Diseases (ECCMID 2022, Lisbon, 23-26 April) shows that, although over time the number of SARS-CoV-2 antibodies falls in both previously infected and vaccinated patients, the performance of antibodies improves only after previous infection (and not vaccination).

11 Feb 2022

Model shows booster doses and antiviral pills may enable relaxation of SARS-CoV-2 social distancing

Researchers suggest that social distancing could be relaxed in order to reduce the number of severe cases of COVID-19, rather than stop the transmission of the SARS-CoV-2.

11 Feb 2022

Spike Protein News and Research

Study confirms that pets can harbor SARS-CoV-2 infection

Research identifies differences between Omicron lineages BA.1 and BA.2

Impact of Omicron on COVID-19 prevalence among unvaccinated and vaccinated in Omicron-dominated countries

Study explores how the electrostatic charge of the SARS-CoV-2 spike protein has changed over time

Omicron RBD-ACE2 binding found to be stronger than wild type SARS-CoV-2 strain

COVID-19 vaccine boosters shown to confer protection against the SARS-CoV-2 Omicron variant

Research suggests SARS-CoV-2 viral accessory proteins may play significant role in viral evolution

Neutralizing antibody levels to different SARS-CoV-2 epitopes fluctuate over time

Antiviral activity assessment of remdesivir against 10 current and former SARS-CoV-2 variant clinical isolates

Novel glycation patterns help understand Omicron immune escape

First survey on Omicron BA.2 in France

Structural protein vimentin facilitates SARS-CoV-2 entry into endothelial cells

Study analyzes antigenic properties of SARS-CoV-2 Omicron sublineages

Study describes a β-CoV spike protein target for protective antibodies that may facilitate pan-β-CoV vaccine development

An alternative strategy targeting furin disrupts SARS-CoV-2 infection cycle

How a third booster BNT162b2 dose impacts anti-spike antibody levels

mRNA-1273 and mRNA-1273.529 Omicron-specific boosters highly effective in mouse model

Study provides evidence for spike protein-independent attenuation of SARS-CoV-2 Omicron variant

Performance of SARS-CoV-2 antibodies improves only after previous infection, not vaccination

Model shows booster doses and antiviral pills may enable relaxation of SARS-CoV-2 social distancing

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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