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Two Rutgers engineers create analytical tool to accelerate the production of biologic drugs

Two Rutgers engineers specializing in the process of making drugs derived from living organisms have created an analytical tool they expect will accelerate the discovery and production of biologic drugs that are often at the cutting edge of biomedical research.

18 May 2022

Recombinant protein vaccine stands up to SARS-CoV-2 variants

A study by researchers in Texas describes a mouse model in which a subunit vaccine with alum-CpG adjuvant was tested for its ability to induce a broadly neutralizing antibody response against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

18 May 2022

Molecular pathway allows cells to sense when their lipid supplies become depleted

UT Southwestern researchers have discovered a molecular pathway that allows cells to sense when their lipid supplies become depleted, prompting a flurry of activity that prevents starvation.

18 May 2022

Researchers test how three mutations work together to produce new SARS-CoV-2 variants

Like storm waves battering a ship, new versions of the SARS-CoV-2 virus have buffeted the world one after another. Recently, scientists keeping tabs on these variants noticed a trend: Many carry the same set of three mutations.

18 May 2022

Genome research explains why oats could be suitable for most people with celiac disease

Ground-breaking new research published in Nature has decoded the genome of oats and explained why the popular cereal could be suitable for most people with coeliac disease and gluten intolerance.

18 May 2022

Scientists report complex mutation pattern of Omicron BA.2

Recently, scientists have studied the mutation profile of SARS-CoV-2 Omicron BA.2 and analyzed its outcome based on the interaction with receptor and/or monoclonal antibodies.

18 May 2022

Only some coronaviruses found to have pandemic-causing potential

In a new study, scientists focused on resolving the mystery of why some coronaviruses have the potential of causing a pandemic while others do not.

18 May 2022

Treatment with imatinib results in lower mortality rates for patients with severe COVID-19

Patients with severe COVID-19 who were given imatinib had lower mortality rates at 90-day follow-up, according to research published at the ATS 2022 international conference.

18 May 2022

Study explores lipid nanoparticles against SARS-CoV-2

Researchers assessed the efficiency of lipid nanoparticles against SARS-CoV-2.

18 May 2022

Triple BNT162b2 vaccination found to establish long-term T lymphocyte immunity among MDS and CLL patients

In a new study, researchers evaluated the BNT162b2 coronavirus disease 2019 mRNA vaccine (antigen)-specific immune response among myeloid dysplastic syndrome and chronic lymphocytic leukemia patients.

18 May 2022

Study explores neurologic complications in pediatric COVID-19 cases

Researchers evaluated neurologic complications in pediatric cases of COVID-19.

18 May 2022

Combined COVID-19 vaccination regimen found to induce more potent anti-SARS-CoV-2 antibodies

Researchers assessed the vaccine-induced humoral responses against SARS-CoV-2 post four different vaccination regimens comprising homologous and heterologous vaccine doses.

18 May 2022

Insight into sustained-release drug delivery systems

In this interview, News-Medical speaks to Thanh T. Nguyen, a project manager at Innocore Pharmaceuticals, about the mechanisms behind long-acting injectables.

From Thermo Fisher Scientific – Pharmaceutical and Biopharmaceutical Solutions 18 May 2022

Case report: human breast milk from vaccinated woman clears persistent SARS-CoV-2 infection

A new study published in the journal Viruses aimed to report the effects of plasma infusion and then breastmilk ingestion as a therapy for persistent SARS-CoV-2 infection in a patient with a common variable immunodeficiency (CVID) phenotype.

18 May 2022

Discovery of a potent SARS-CoV-2 RBD specific human monoclonal antibody

A recent article posted to the bioRxiv* preprint server demonstrated structural underpinnings of the neutralization of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variants by 002-S21F2, an extensive SARS-CoV-2 neutralizing antibody.

18 May 2022

Researchers create artificial cell membrane that can be kept stable for over 50 days

In nature, the cell membrane has a unique function of protecting the internal from the external environment and communicating outside by sensing the external chemical or physical stimuli like the most precise biosensor for life.

18 May 2022

Impact of cannabidiol on cellular innate immune responses to SARS-CoV-2 genes

A new study published in the journal Life Sciences has focused on examining the effects of ORF8 and ORF10 genes and SARS-CoV-2 Membrane (M) protein on apoptosis.

17 May 2022

Camelid IFNs could play important role in combating emerging zoonotic pathogens

In a recent study published in the Developmental & Comparative Immunology journal, the discovery of a novel form of mammalian interferon-Beta (IFN-β) with four cysteine residues from the dromedary camel and the five remaining members of the mammalian suborder Tylopoda is described.

17 May 2022

Experimental drug more effective than existing FDA-approved medications for ALS

New research on the experimental drug, NU-9, invented and developed by two Northwestern University scientists to treat ALS (amyotrophic lateral sclerosis), shows it is more effective than existing FDA-approved drugs for the disease.

17 May 2022

Exploring mutational energetics and the role of arginine blockers in COVID-19 treatments

A new study aimed to describe the roles of certain specific mutations in SARS-CoV-2 strains, with respect to their ability to conformationally stabilize S-protein structure resulting in enhanced receptor-binding domain ACE2 binding.

17 May 2022

Protein C News and Research

Two Rutgers engineers create analytical tool to accelerate the production of biologic drugs

Recombinant protein vaccine stands up to SARS-CoV-2 variants

Molecular pathway allows cells to sense when their lipid supplies become depleted

Researchers test how three mutations work together to produce new SARS-CoV-2 variants

Genome research explains why oats could be suitable for most people with celiac disease

Scientists report complex mutation pattern of Omicron BA.2

Only some coronaviruses found to have pandemic-causing potential

Treatment with imatinib results in lower mortality rates for patients with severe COVID-19

Study explores lipid nanoparticles against SARS-CoV-2

Triple BNT162b2 vaccination found to establish long-term T lymphocyte immunity among MDS and CLL patients

Study explores neurologic complications in pediatric COVID-19 cases

Combined COVID-19 vaccination regimen found to induce more potent anti-SARS-CoV-2 antibodies

Insight into sustained-release drug delivery systems

Case report: human breast milk from vaccinated woman clears persistent SARS-CoV-2 infection

Discovery of a potent SARS-CoV-2 RBD specific human monoclonal antibody

Researchers create artificial cell membrane that can be kept stable for over 50 days

Impact of cannabidiol on cellular innate immune responses to SARS-CoV-2 genes

Camelid IFNs could play important role in combating emerging zoonotic pathogens

Experimental drug more effective than existing FDA-approved medications for ALS

Exploring mutational energetics and the role of arginine blockers in COVID-19 treatments

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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