Inflammation News and Research

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Researchers discover new type of antigen-presenting immune cell

With a discovery that could rewrite the immunology textbooks, an international group of scientists, including the teams of Bart Lambrecht, Martin Guilliams, Hamida Hammad, and Charlotte Scott (all from the VIB-UGent Center for Inflammation Research) identified a new type of antigen-presenting immune cell.

8 May 2020

Gene therapy helps build muscle mass and reduces severity of osteoarthritis in mice

Exercise and physical therapy often are recommended to help people who have arthritis. Both can strengthen muscle - a benefit that also can reduce joint pain.

8 May 2020

The nutritional key to control autoimmunity and cancer

Scientists at the Department of Infection and Immunity of the Luxembourg Institute of Health revealed a novel mechanism through which the immune system can control autoimmunity and cancer.

8 May 2020

EULAR publishes recommendations for management of rheumatic immune-related adverse events

The European League Against Rheumatism, EULAR, has published recommendations around rheumatic immune-related adverse events caused by cancer treatment with checkpoint inhibitors.

8 May 2020

HMGB1 protein may play a key role in pulmonary inflammation, tissue damage in severe COVID-19 cases

In severe cases of COVID-19, a massive release of the endogenous protein HMGB1 in the lungs may contribute to pulmonary inflammation and tissue damage, according to a review article published today in the scientific journal Molecular Medicine.

8 May 2020

Scientists discover new metabolism regulation system for the brown adipose tissue

Scientific team found a new metabolism regulation system for the brown adipose tissue using the kallikrein-kinin hormonal system, so far related to the physiology of the renal and cardiovascular system and inflammation and pain processes.

8 May 2020

New compound significantly reduces multiple pathologies linked to Alzheimer's disease

When tested in brain cells and in a mouse model of Alzheimer's disease, a new compound significantly reduced the number of amyloid plaques in the brain, lessened brain inflammation and diminished other molecular markers of the disease.

8 May 2020

Pangolins may be the key to new COVID-19 treatments

Researchers at the Medical University of Vienna, Austria, have made an important discovery about the immune response to coronaviruses in pangolins that could point to new approaches for treating human cases of infection.

8 May 2020

Some foods common in diets of adults with inflammatory bowel disease

American researchers from the Institute for Biomedical Sciences at Georgia State University have found that certain foods such as cheese, cookies, French fries, energy drinks, soda, and other types of junk foods are found more frequently in the diets of adults suffering from inflammatory bowel disease (IBD).

7 May 2020

SARS-CoV-2 found in semen of COVID-19 patients

Since the novel coronavirus, now called the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), emerged in December 2019, viral loads have been detected in body fluids, such as urine samples, saliva, stool samples, and in the gastrointestinal tract. Now, a new study reveals the SARS-CoV-2 virus in semen.

7 May 2020

Vitamin D could improve outcomes in COVID-19

A new study published on the preprint server medRxiv* in May 2020 shows that vitamin D could have a beneficial effect on the course of illness for COVID-19 patients.

7 May 2020

Modified dialysis device treats COVID-19

As part of a randomized controlled trial, a team from Lawson Health Research Institute is the first in the world to treat a patient with COVID-19 using a modified dialysis device.

7 May 2020

IONTAS announces a new collaboration to identify novel immunotherapy targets

Antibody discovery agreement will support the development of new therapeutics for acute and chronic inflammatory syndromes.

From FairJourney Biologics 7 May 2020

Cholesterol lowering drugs can improve composition of gut bacteria in obese individuals

The human gut microbiota consists of trillions of bacteria, fungi and virus constituting an inner chemical factory producing a multitude of microbial compounds affecting immunity, neurobiology and metabolism of the human host.

7 May 2020

Researchers show how bats carry the MERS coronavirus

A University of Saskatchewan (USask) research team has uncovered how bats can carry the Middle East respiratory syndrome (MERS) coronavirus without getting sick--research that could shed light on how coronaviruses make the jump to humans and other animals.

7 May 2020

AI-enabled precision medicine may increase survival rate of patients with COVID-19-related sepsis

Data scientists from UK-headquartered AI precision medicine company, PrecisionLife, have used the Company’s proprietary AI enabled precision medicine platform to identify 59 repurposing drug candidates that could be used to develop new therapeutic strategies to increase the survival rate of patients who develop sepsis while suffering from severe COVID-19.

7 May 2020

Air pollution associated with greater virulence of COVID-19

A new study published on the preprint server medRxiv* in April 2020 provides convincing evidence that air pollution contributes to greater severity of COVID-19. The researchers say, “This suggests the detrimental impact climate change will have on the trajectory of future respiratory epidemics.”

6 May 2020

Study discovers inhibition of SARS-CoV-2 entry priming protein by approved drug

The COVID-19 pandemic caused by the severe acute respiratory syndrome -coronavirus 2 (SARS-CoV-2) has spread to most of the world, causing millions of cases and hundreds of thousands of deaths. A new study published on the preprint server bioRxiv* shows that a protease inhibitor drug already approved by the Food and Drug Administration (FDA) could inhibit viral entry.

6 May 2020

Low CD8 and NK cell counts in the lung linked to high SARS-CoV-2 ACE2 receptor levels

A new study published on the preprint server bioRxiv in April 2020 reports that low levels of specific immune cells, namely, CD8 T cells and NK cells, are linked to higher expression of the ACE2 molecule, which acts as a receptor for the CoV.

6 May 2020

Study finds race-specific lupus nephritis biomarkers for early diagnosis, treatment

University of Houston Hugh Roy and Lillie Cranz Cullen Endowed Professor of biomedical engineering, Chandra Mohan, and his team have discovered a difference in urinary biomarker proteins of lupus nephritis in patients according to race.

6 May 2020

Inflammation News and Research

Researchers discover new type of antigen-presenting immune cell

Gene therapy helps build muscle mass and reduces severity of osteoarthritis in mice

The nutritional key to control autoimmunity and cancer

EULAR publishes recommendations for management of rheumatic immune-related adverse events

HMGB1 protein may play a key role in pulmonary inflammation, tissue damage in severe COVID-19 cases

Scientists discover new metabolism regulation system for the brown adipose tissue

New compound significantly reduces multiple pathologies linked to Alzheimer's disease

Pangolins may be the key to new COVID-19 treatments

Some foods common in diets of adults with inflammatory bowel disease

SARS-CoV-2 found in semen of COVID-19 patients

Vitamin D could improve outcomes in COVID-19

Modified dialysis device treats COVID-19

IONTAS announces a new collaboration to identify novel immunotherapy targets

Cholesterol lowering drugs can improve composition of gut bacteria in obese individuals

Researchers show how bats carry the MERS coronavirus

AI-enabled precision medicine may increase survival rate of patients with COVID-19-related sepsis

Air pollution associated with greater virulence of COVID-19

Study discovers inhibition of SARS-CoV-2 entry priming protein by approved drug

Low CD8 and NK cell counts in the lung linked to high SARS-CoV-2 ACE2 receptor levels

Study finds race-specific lupus nephritis biomarkers for early diagnosis, treatment

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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