Protein News and Research

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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

Cryo-electron tomography helps visualize platelet deformation due to SARS-CoV-2 spike protein

Researchers used cellular cryo-electron tomography (cryo-ET) to demonstrate the role of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) protein in coronavirus disease 2019 (COVID-19)-triggered severe coagulopathies.

28 Nov 2022

Possibility of the first fluid biomarker that reflects brain pathology in primary tauopathies

Addressing this gap in research, a recent Nature Medicine study hypothesized that 4R isoform-specific MTBR-tau species accumulate in the patient’s brain of specific subtypes of 4R tauopathies.

28 Nov 2022

Glycan signatures in rheumatic diseases and their associated functional implications

A new paper examines the understanding of glycosylation in an array of rheumatic diseases and indicates the potential for therapeutic interventions using the same mechanism.

28 Nov 2022

Should older seniors risk major surgery? New research offers guidance

Nearly 1 in 7 older adults die within a year of undergoing major surgery, according to an important new study that sheds much-needed light on the risks seniors face when having invasive procedures.

28 Nov 2022

New chemical probe can selectively inhibit human COQ8A protein in cells

Inhibition of the COQ8 protein could be beneficial in the treatment of diseases such as cancer. COQ8 is needed for the biosynthesis of coenzyme Q, also known as ubiquinone.

28 Nov 2022

Flavonoids with potential to fight allergies and inflammation

In a recent study published in the Biomedicine & Pharmacotherapy journal, researchers explored the anti-allergic and anti-inflammatory properties of flavonoids.

28 Nov 2022

Are nasal-spray vaccines the solution to respiratory infectious diseases?

A recent study published in the journal Trends in Molecular Medicine reviewed the current efforts in developing nasal vaccines, delivery systems, and clinical applications for preventing respiratory illnesses.

28 Nov 2022

Memory B and T cells responses differ when induced by SARS-CoV-2 infections or booster vaccinations

In a recent study published in The Journal of Immunology, a team of researchers from Japan examined the memory B and T cell responses to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein after the booster dose of the coronavirus disease 2019 (COVID-19) messenger ribonucleic acid (mRNA) vaccine BNT162b2.

27 Nov 2022

Nanoparticles displaying SARS-CoV-1 and SARS-CoV-2 spikes induce broad antibody responses in animal model

A recent study published in the journal iScience reported that nanoparticles (NPs) co-displaying spike proteins from different sarbecoviruses improve the breadth of neutralizing responses.

27 Nov 2022

The distinct pathophysiology of ‘SuperAger’ brains

Superagers are adults over the age of 80 who have a superior memory capacity that resembles that of middle-aged adults.

27 Nov 2022

Klotho protein levels protect against cognitive decline in Alzheimer patients

Researchers compare Klotho protein levels of healthy individuals and patients diagnosed with different stages of Alzheimer’s disease.

27 Nov 2022

MicroRNAs play a key role in the development of complex brains

Cephalopods like octopuses, squids and cuttlefish are highly intelligent animals with complex nervous systems.

25 Nov 2022

Researchers discover a new function of CRISPR/Cas9 gene scissors

For several years now, the CRISPR/Cas9 gene scissors have been causing a sensation in science and medicine.

25 Nov 2022

Multivalent mRNA-based vaccine may serve as a preventative measure against future flu pandemics

An experimental mRNA-based vaccine against all 20 known subtypes of influenza virus provided broad protection from otherwise lethal flu strains in initial tests, and thus might serve one day as a general preventative measure against future flu pandemics, according to researchers from the Perelman School of Medicine at the University of Pennsylvania.

25 Nov 2022

Scientists investigate the evolutionary origin of SARS-CoV-2 using recombination-aware phylogenetic analysis

A study has employed Bacter to identify recombination events with the RBD regions of the Sarbecovirus genome.

25 Nov 2022

The potential of Sofosbuvir against COVID-19 neurological symptoms

Researchers discuss how SARS-CoV-2 infects cortical neurons and damages their synapses that form the connection between brain cells.

25 Nov 2022

New approach may serve as the basis for universal flu vaccines

Claudia Arevalo and colleagues have developed a mRNA lipid nanoparticle vaccine that contains antigens from all 20 known subtypes of influenza A and B viruses, a strategy that may serve as the basis for universal flu vaccines.

24 Nov 2022

New biomarker can help identify people with a primary tauopathy

Zooming in on a single disease and studying it intensely is often the most productive route to finding treatments. But there's no easy way to distinguish among people living with any of the primary tauopathies - a group of rare brain diseases marked by rapidly worsening problems with thinking and movement - because the symptoms are too similar.

24 Nov 2022

New CRISPR-based tool can snip out faulty genes and replace them with new ones

Building on the CRISPR gene-editing system, MIT researchers have designed a new tool that can snip out faulty genes and replace them with new ones, in a safer and more efficient way.

24 Nov 2022

Novel cancer-fighting nanoparticles co-deliver a chemotherapy drug and immunotherapy

University of Pittsburgh researchers have designed cancer-fighting nanoparticles that co-deliver a chemotherapy drug and a novel immunotherapy, according to a new Nature Nanotechnology study published today.

24 Nov 2022

Protein News and Research

Further Reading

Cryo-electron tomography helps visualize platelet deformation due to SARS-CoV-2 spike protein

Possibility of the first fluid biomarker that reflects brain pathology in primary tauopathies

Glycan signatures in rheumatic diseases and their associated functional implications

Should older seniors risk major surgery? New research offers guidance

New chemical probe can selectively inhibit human COQ8A protein in cells

Flavonoids with potential to fight allergies and inflammation

Are nasal-spray vaccines the solution to respiratory infectious diseases?

Memory B and T cells responses differ when induced by SARS-CoV-2 infections or booster vaccinations

Nanoparticles displaying SARS-CoV-1 and SARS-CoV-2 spikes induce broad antibody responses in animal model

The distinct pathophysiology of ‘SuperAger’ brains

Klotho protein levels protect against cognitive decline in Alzheimer patients

MicroRNAs play a key role in the development of complex brains

Researchers discover a new function of CRISPR/Cas9 gene scissors

Multivalent mRNA-based vaccine may serve as a preventative measure against future flu pandemics

Scientists investigate the evolutionary origin of SARS-CoV-2 using recombination-aware phylogenetic analysis

The potential of Sofosbuvir against COVID-19 neurological symptoms

New approach may serve as the basis for universal flu vaccines

New biomarker can help identify people with a primary tauopathy

New CRISPR-based tool can snip out faulty genes and replace them with new ones

Novel cancer-fighting nanoparticles co-deliver a chemotherapy drug and immunotherapy

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