Inflammation News and Research

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University of Utah invests $1.3 million in multidisciplinary COVID-19 research projects

As the COVID-19 pandemic continues to spread across the globe, University of Utah scientists are at the forefront of efforts to learn more about how to lasso the virus that causes it and understand its potential long-term social, economic, and psychological effects.

20 Apr 2020

ATS publishes first official clinical practice guidelines for sarcoidosis

New guidance is available for physicians who must go through a number of steps to provide a probable diagnosis of sarcoidosis - an inflammatory disease that affects the lungs, lymph glands, and other organs.

20 Apr 2020

COVID-19 lung injury is not like high altitude pulmonary edema

A group of researchers with experience in treating high altitude pulmonary edema have written to correct the misconception in medical social media forums and elsewhere that the lung injury seen in COVID-19 is not like typical acute respiratory distress syndrome and is instead like HAPE.

20 Apr 2020

Male-female cardiac repair differences found in heart failure survival after heart attack

The short-term acute inflammatory response triggered to mend injured cardiac tissue following a heart attack can lead to weakening of the heart's pumping function if the inflammation remains active over the long-term.

20 Apr 2020

Study reveals new therapeutic options for multiple sclerosis

Multiple sclerosis is known as "the disease with a thousand faces" because symptoms and progression can vary dramatically from patient to patient.

20 Apr 2020

Potential new therapies for multiple sclerosis

In every MS patient cells of their body's own immune system migrate to the brain, where they destroy the myelin sheath.

20 Apr 2020

Study shows how interactions between microbiome and the immune system contribute to liver disease

A new study by researchers in the Quadram Institute has provided insights into how interactions between gut microbes and cells of the immune system contribute to cholestatic liver disease.

20 Apr 2020

Study adds increasing evidence that autoimmunity plays a role in Parkinson's disease

A new study co-led by scientists at the La Jolla Institute for Immunology adds increasing evidence that Parkinson's disease is partly an autoimmune disease. In fact, the researchers report that signs of autoimmunity can appear in Parkinson's disease patients years before their official diagnosis.

20 Apr 2020

New research gives further evidence that autoimmunity plays a role in Parkinson's disease

A new study adds increasing evidence that Parkinson's disease is partly an autoimmune disease.

20 Apr 2020

Smoking doubles risk of severe COVID-19 disease

The fatality rate among infected people increases among the elderly and those with underlying medical conditions. Now, a new study published as a pre-print on medXriv, links smoking to the progression of COVID-19 disease, suggesting that the odds of disease progression is more than double in smokers.

20 Apr 2020

Salk scientists uncover surprising role of tuft cells in pancreatitis

Persistent inflammation of the pancreas (chronic pancreatitis) is a known risk factor for developing pancreatic cancer, the third-deadliest cancer in the United States.

18 Apr 2020

Polycistronic delivery of IL-10 and NT-3 to enhance spinal cord injury repair

Spinal cord injury creates a complex microenvironment that is not conducive to repair; growth factors are in short supply, whereas factors that inhibit regeneration are plentiful.

18 Apr 2020

Cancer immunotherapy can lead to inflammation of the heart muscle

Immunotherapy is a powerful weapon in the fight against cancer, but inflammation of the heart muscle (myocarditis) is one of its most serious side effects.

17 Apr 2020

Gimsilumab trial starts in first US patient with ARDS and COVID-19

The first American patient with COVID-19 and acute respiratory distress syndrome (ARDS) has been put on the drug gimsilumab at Temple University Hospital, as part of the BREATHE clinical trial. The trial, sponsored by Roivant Sciences, will evaluate the effectiveness of intravenous gimsilumab in preventing death in patients with COVID-19 and ARDS.

16 Apr 2020

Are overactive immune cells causing COVID-19-related deaths?

While the COVID-19 pandemic is devastating many regions, the world over, a new paper published in the Journal of Experimental Medicine in April 2020 describes the possibility that the critical or very severe cases of COVID-19 are due to the production of neutrophil extracellular traps (NET) due to hyperactivated immune cells.

16 Apr 2020

Gold-containing drug auranofin kills 95% of SARS-CoV-2 virus in 48 hours in lab conditions

A drug called auranofin, approved for the treatment of rheumatoid arthritis, effectively inhibits severe acute respiratory syndrome coronavirus (SARS-CoV-2) in laboratory conditions, as described in a new study by Georgia State University researchers.

16 Apr 2020