Inflammation News and Research

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New therapeutic approach for preserving inflammation-free phases of Crohn's disease

Intestinal stem cell metabolism is facilitated by mitochondria - the in-cell power plants. Chronic inflammation processes inhibit the cells' metabolism and lead to functional loss of these stem cells.

15 Apr 2020

Bacterial metabolism of bile acids boosts generation of immune cells, study shows

A Ludwig Cancer Research study has discovered a novel means by which bacterial colonies in the small intestine support the generation of regulatory T cells--immune cells that suppress autoimmune reactions and inflammation.

15 Apr 2020

COVID-19 and type 2 diabetes have shared disease pathways, study finds

Individuals with diabetes are at increased risk for bacterial, parasitic and viral infections. New research published in Endocrine Reviews, a journal of the Endocrine Society, illuminates how intersections of the coronavirus infection (COVID-19) and type 2 diabetes may require new approaches in treatment for hospitalized patients.

15 Apr 2020

China with the world: COVID-19 experts dialogues - the 4th talk transcript

Q (Prof. Singer): What do you think about the comorbidities and the age of the patients in the treatment of COVID-19? Is the mortality higher in elderly patients as it is reported from recent papers?

From Mindray 15 Apr 2020

Discovery of T cells response spectrum could new shed light on immune diseases

The discovery that immune T cells have a spectrum of responsiveness could shed light on how our immune system responds to infections and cancer, and what goes wrong in immune diseases.

15 Apr 2020

New vaccine for Chikungunya reported safe and well-tolerated

A virus-like particle vaccine was shown to be safe and well-tolerated among a healthy adult population living in chikungunya endemic areas, the researchers report in a new study published in the Journal of the American Medical Association (JAMA).

14 Apr 2020

Women born by cesarean have greater risk of obesity and diabetes

A new study published in the open-access journal JAMA Network Open in April 2020 suggests that women born by way of a Cesarean section are at higher risk of developing obesity as well as type 2 diabetes mellitus in adult life.

13 Apr 2020

Could DPP4 inhibitors help treat COVID-19?

Researchers and clinicians are scrambling to find ways to combat COVID-19, including new therapeutics and eventually a vaccine.

13 Apr 2020

How does COVID-19 attack the body?

The coronavirus disease (COVID-19) attacks the lungs, leading to pneumonia, and eventually, a cascade of serious complications. But how does COVID-19 kill? Is it the virus itself or the result of the person’s immune system response?

13 Apr 2020

Lasers turn metal surfaces into bacteria killers

Purdue University researchers have discovered a laser treatment to texture metals that can potentially transform almost any metal surface into one that quickly eliminates any bacteria that come into contact with it.

12 Apr 2020

PARP inhibitor drugs can be structurally modified to better kill tumor cells

A prospective "PARP inhibitor" drug that has struggled to show effectiveness in clinical trials against cancers can be structurally modified to greatly increase its power to kill tumor cells, researchers from Penn Medicine report this week in Science.

12 Apr 2020

Where cancers spread can give specific insights on disease traits

Kidney cancers that metastasize to the pancreas have a fundamentally different biology from those that metastasize elsewhere, with characteristics that can influence successful treatment, a study led by investigators with the UT Southwestern Kidney Cancer Program suggests.

12 Apr 2020

New clinical trial launches to test efficacy of cell therapy for severe COVID-19 cases

After a lightening round of proposals and reviews, an international team of scientists led by Dr. Camillo Ricordi was granted immediate FDA authorization for a 24-patient clinical trial to test the safety and exploratory efficacy of umbilical cord-derived mesenchymal stem cells to block the life-threatening lung inflammation that accompanies severe cases of COVID-19.

11 Apr 2020

Hypertensive patients on ACE inhibitors and angiotensin receptor blockers may have improved COVID-19 prognosis

Emerging concerns that common antihypertensive treatment approaches with angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin receptor blockers (ARBs) – jointly known as renin-angiotensin-aldosterone system (RAAS) inhibitors – may exert a negative effect in COVID-19 patients are not grounded in scientific evidence, as reported by researchers in a recent review article published in Mayo Clinic Proceedings journal.

9 Apr 2020

Probiotics may help augment skin's natural defenses against acne

Acne is caused by chronic inflammation and is often treated with antibiotics.

9 Apr 2020

‘Entry Point’ enzyme for COVID-19 higher in COPD patients and smokers

News-Medical speaks to Professor Don Sin on his research into COVID-19 and its effect on smokers and people suffering from COPD.

9 Apr 2020

What does recovery from COVID-19 look like? It depends. A pulmonologist explains.

Reports of recovery from serious illness caused by the coronavirus have been trickling in from around the world.

9 Apr 2020

Novel coronavirus targets specific secretory cells in the lungs

Viruses attack specific host cells, which can cause chaos in the body. The novel coronavirus, now called severe acute respiratory syndrome coronavirus 2 or SARS-CoV-2 for short, infects respiratory epithelial cells in the lining of the lung, causing difficulty of breathing. The usual cause of death of those who contract the virus is pneumonia and acute respiratory distress syndrome (ARDS). Now, a new study has found that SARS-CoV-2 specifically attack certain progenitor cells called bronchial transient secretory cells in the lungs.

9 Apr 2020

Ai used to detect COVID-19 pneumonia

Coronaviruses have 'spilled over' to human populations throughout history, causing respiratory illnesses, often associated with pneumonia. The severe acute respiratory syndrome (SARS), which emerged in 2002 in China, and the Middle East Respiratory Syndrome (MERS), which was first seen in Saudi Arabia in 2012, are similar to the current global pandemic spreading worldwide, the coronavirus disease (COVID-19).

9 Apr 2020

Short-term exposure to even low levels of air pollution can affect gene expression

New data from a landmark study done by Monash University researchers in Australia raises significant concerns that even short-term exposure to low level air pollution can affect gene expression, leaving us at risk of other diseases such as cancer, cardiovascular and respiratory diseases.

8 Apr 2020