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Protein Society member and Anfinsen Award recipient receive 2013 Nobel Prize in Chemistry

The Protein Society, the leading international society dedicated to advancing research in to protein structure, function, design and applications, announces long-time member Michael Levitt (Stanford University School of Medicine) and 2001 Anfinsen Award recipient Martin Karplus (Universit- de Strasbourg, France and Harvard University), have been awarded the 2013 Nobel Prize in Chemistry.

11 Oct 2013

Gene mutation offers clues to development of diverse neurological disorders

A research team, headed by Theodore Friedmann, MD, professor of pediatrics at the University of California, San Diego School of Medicine, says a gene mutation that causes a rare but devastating neurological disorder known as Lesch-Nyhan syndrome appears to offer clues to the developmental and neuronal defects found in other, diverse neurological disorders like Alzheimer's, Parkinson's and Huntington's diseases.

10 Oct 2013

Molecular Templates secures $8.5M series C financing plus $10.6M grant from CPRIT

Molecular Templates, Inc., a biopharmaceutical company focused on the discovery and development of a new class of biologic therapeutics, announced today that it recently secured an $8.5M series C financing led by Excel Venture Management. Santé Ventures, an existing investor, also participated in the round.

9 Oct 2013

Understanding the biological players in clot formation could lead to new thrombotic therapies

Ulhas Naik, professor of biological sciences and director of the Delaware Cardiovascular Research Center, pores over laboratory data on his computer, even during breakfast most mornings. He is on a quest to tease out the roles that various blood components play in the formation of clots.

9 Oct 2013

New mathematical model predicts biological process that creates antibody diversity

Scientists at USC have created a mathematical model that explains and predicts the biological process that creates antibody diversity - the phenomenon that keeps us healthy by generating robust immune systems through hypermutation.

9 Oct 2013

Retinitis pigmentosa test identifies mutation found in Ashkenazi Jewish population

You might not think to look to a urine test to diagnose an eye disease. But a new Duke University study says it can link what is in a patient's urine to gene mutations that cause retinitis pigmentosa, or RP, an inherited, degenerative disease that results in severe vision impairment and often blindness. The findings appear online in the Journal of Lipid Research.

9 Oct 2013

Alnylam advances Development Candidate for ALN-AS1 for treatment of hepatic porphyrias

Alnylam Pharmaceuticals, Inc. (Nasdaq: ALNY), a leading RNAi therapeutics company, announced today that it is advancing its Development Candidate for ALN-AS1, an RNAi therapeutic targeting aminolevulinate synthase-1 (ALAS-1) for the treatment of hepatic porphyrias including acute intermittent porphyria (AIP).

9 Oct 2013

Acorda Therapeutics initiates second clinical trial of Glial Growth Factor 2 in heart failure patients

Acorda Therapeutics, Inc. (Nasdaq: ACOR) today announced that the first patient has been enrolled in the second clinical trial of Glial Growth Factor 2 (GGF2). This Phase 1b single-infusion trial in people with heart failure will assess tolerability of three dose levels of GGF2, and also includes several explorative measures of efficacy.

9 Oct 2013

Blocking pathway might prevent esophageal cancer in patients with existing Barrett's esophagus

Got heartburn? More than 60 million adults in the U.S. have acid reflux, or heartburn, and approximately 10 percent are at risk for developing esophageal cancer, due in part to complications from Barrett's esophagus.

8 Oct 2013

Two researchers receive $2.5M grant to continue their research on cancer cell growth

A pair of researchers at Rutgers Cancer Institute of New Jersey has been awarded nearly $2.5 million dollars to further study in their respective laboratories.

8 Oct 2013

Researchers create catalyst that alters chemical profiles of numerous types of small molecules

Researchers report that they have created a man-made catalyst that is an "enzyme mimic." Unlike most enzymes, which act on a single target, the new catalyst can alter the chemical profiles of numerous types of small molecules.

7 Oct 2013

$Binge drinking can impair healing process following bone fracture$

Binge drinking can impair healing process following bone fracture

Physicians have long observed that binge drinking can significantly impair the healing process following a bone fracture.

7 Oct 2013

Researchers reveals mechanism of sodium-potassium pump in cell

It's not visible to the naked eye and you can't feel it, but up to 40 per cent of your body's energy goes into supplying the microscopic sodium-potassium pump with the energy it needs. The pump is constantly doing its job in every cell of all animals and humans. It works much like a small battery which, among other things, maintains the sodium balance which is crucial to keep muscles and nerves working.

5 Oct 2013

New biomarker for pancreatic cancer effectively targets potential therapy for small survival rate

University of Cincinnati (UC) researchers have discovered a biomarker, known as phosphatidylserine (PS), for pancreatic cancer that could be effectively targeted, creating a potential therapy for a condition that has a small survival rate.

5 Oct 2013

Bioactive compounds in carrot can be used as antiviral for treatment against flu

Researchers from the FEMSA Center of Biotechnology at Technologic of Monterrey (ITESM) designed a technology that uses grated carrot to obtain phenolic compounds that have a potential to prevent cancer, and cardiovascular and neurodegenerative diseases.

5 Oct 2013

Metabolic enzymes in opium poppy are used to produce valuable painkilling drugs

University of Calgary scientists have discovered metabolic enzymes in the opium poppy that play "widespread roles" in enabling the plant to make painkilling morphine and codeine, and other important compounds.

5 Oct 2013

Modern strains of MRSA have become broadly resistant to antibiotics: Study

University of Notre Dame researchers Shahriar Mobashery and Mayland Chang and their collaborators in Spain have published research results this week that show how methicillin-resistant Staphylococcus aureus (MRSA) regulates the critical crosslinking of its cell wall in the face of beta-lactam antibiotics.

5 Oct 2013

Scientists identify chemical agents that block flu virus's ability to replicate itself in cell culture

A new way to attack flu viruses is taking shape in laboratories at Rutgers University, where scientists have identified chemical agents that block the virus's ability to replicate itself in cell culture.

4 Oct 2013

PET/CT imaging provides valuable insight to predict risk of rupture abdominal aortic aneurysms

Several newly identified markers could provide valuable insight to predict the risk of rupture abdominal aortic aneurysms (AAA), according to new research published in the October issue of the Journal of Nuclear Medicine.

4 Oct 2013

Selenium in plants causes mortality and delays development in honey bee, say researchers

Traditionally, honey bee research has focused on environmental stressors such as pesticides, pathogens and diseases. Now a research team led by entomologists at the University of California, Riverside has published a study that focuses on an anthropogenic pollutant: selenium (Se).

4 Oct 2013

Enzyme News and Research

Protein Society member and Anfinsen Award recipient receive 2013 Nobel Prize in Chemistry

Gene mutation offers clues to development of diverse neurological disorders

Molecular Templates secures $8.5M series C financing plus $10.6M grant from CPRIT

Understanding the biological players in clot formation could lead to new thrombotic therapies

New mathematical model predicts biological process that creates antibody diversity

Retinitis pigmentosa test identifies mutation found in Ashkenazi Jewish population

Alnylam advances Development Candidate for ALN-AS1 for treatment of hepatic porphyrias

Acorda Therapeutics initiates second clinical trial of Glial Growth Factor 2 in heart failure patients

Blocking pathway might prevent esophageal cancer in patients with existing Barrett's esophagus

Two researchers receive $2.5M grant to continue their research on cancer cell growth

Researchers create catalyst that alters chemical profiles of numerous types of small molecules

Binge drinking can impair healing process following bone fracture

Researchers reveals mechanism of sodium-potassium pump in cell

New biomarker for pancreatic cancer effectively targets potential therapy for small survival rate

Bioactive compounds in carrot can be used as antiviral for treatment against flu

Metabolic enzymes in opium poppy are used to produce valuable painkilling drugs

Modern strains of MRSA have become broadly resistant to antibiotics: Study

Scientists identify chemical agents that block flu virus's ability to replicate itself in cell culture

PET/CT imaging provides valuable insight to predict risk of rupture abdominal aortic aneurysms

Selenium in plants causes mortality and delays development in honey bee, say researchers

Understanding the DNA Damage Response in Innate Immunity eBook

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo