Immunodeficiency News and Research

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Immunodeficiency (or immune deficiency) is a state in which the immune system's ability to fight infectious disease is compromised or entirely absent.

Scientists find evidence of link between coronavirus and neurological disease

For the first time, researchers have found proof of a direct association between strain OC 43 of the human coronavirus (HCoV) and neurological disease in humans.

3 Oct 2016

MU researcher awarded $3 million NIH grant to develop new drugs for treating HBV

Hepatitis B (HBV) is a viral infection that increases the likelihood of developing liver cancer or liver failure.

26 Sep 2016

Researchers develop innovative technique for detecting HIV hiding places in infected patients

Discovery of a novel, advanced technique to identify the rare cells where human immunodeficiency virus (HIV) hides in patients taking antiretroviral therapy (ART). This is an important step forward in the search for a HIV/AIDS cure.

19 Sep 2016

Scientists reveal underlying mechanisms leading to microcephaly in NBS patients

Scientists from Jerusalem and Duesseldorf have succeeded in generating induced pluripotent stem cells from a rare disorder called Nijmegen breakage syndrome (NBS) and to push these cells to become early neurons, revealing the mechanisms leading to the neurological phenotype observed in these patients.

9 Sep 2016

Researchers discover second line of defense in macaques co-infected with Mtb and SIV

Tulane University researchers found some monkeys whose immune systems are depleted by the simian strain of HIV have a second line of defense against tuberculosis.

7 Sep 2016

HIV-infected adults with MDD more likely to experience heart attack, study shows

Among more than 26,000 human immunodeficiency virus (HIV)-infected adults, those with major depressive disorder (MDD) were more likely to experience a heart attack than those without MDD, according to a study published online by JAMA Cardiology.

24 Aug 2016

Added benefit of combination drug for HIV-infected patients not proven

The drug combination emtricitabine/tenofovir alafenamide is approved in combination with other antiviral agents for the treatment of adults and adolescents infected with human immunodeficiency virus type 1 (HIV-1).

19 Aug 2016

New research examines biomechanics of galectin-3

A new study, published in Biochemistry this week, examines the biomechanics of sugar-seeking proteins. Specifically, it delves into galectin-3's interaction with glycosaminoglycans (GAG) and proteoglycans.

5 Aug 2016

Research could provide new insights into finding cure for chronic infections

New research has taken us a step closer to finding a cure for human immunodeficiency virus (HIV), as well as other infections including the glandular fever virus, which is associated with the development of lymphoma.

4 Aug 2016

Researchers develop new hybrid method to study HIV protein involved in disease progression

More than 36 million people worldwide, including 1.2 million in the U.S., are living with an HIV infection. Today's anti-retroviral cocktails block how HIV replicates, matures and gets into uninfected cells, but they can't eradicate the virus.

3 Aug 2016

People with filariasis show two to three-fold increased risk for HIV

Since the start of the HIV epidemic, there have been speculations as to why HIV and the immunodeficiency syndrome it causes have spread so much more in Africa than in other countries around the world.

3 Aug 2016

Study shows link between inflammatory biomarkers and prevalence of CAD in HIV-infected men

A cardiac imaging study led by Hossein Bahrami, MD, PhD, assistant professor of cardiovascular medicine at the Keck School of Medicine of the University of Southern California, along with investigators from Johns Hopkins University and five other institutions, showed a correlation between higher inflammatory biomarkers and an increased prevalence of coronary artery disease (CAD) in men infected with human immunodeficiency virus (HIV).

3 Aug 2016

CD4/CD8 ratio biomarker could help identify HIV-infected individuals at risk for heart disease

The ratio of CD4 to CD8 T cells in the blood-a marker of immune system health and associated with mortality risk in the general population-is an independent predictor of coronary heart disease in HIV-infected patients, according to a new study published in AIDS Research and Human Retroviruses, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers.

29 Jul 2016

Immunodeficiency News and Research

Further Reading

Scientists find evidence of link between coronavirus and neurological disease

MU researcher awarded $3 million NIH grant to develop new drugs for treating HBV

Researchers develop innovative technique for detecting HIV hiding places in infected patients

Scientists reveal underlying mechanisms leading to microcephaly in NBS patients

Researchers discover second line of defense in macaques co-infected with Mtb and SIV

HIV-infected adults with MDD more likely to experience heart attack, study shows

Added benefit of combination drug for HIV-infected patients not proven

New research examines biomechanics of galectin-3

Research could provide new insights into finding cure for chronic infections

Researchers develop new hybrid method to study HIV protein involved in disease progression

People with filariasis show two to three-fold increased risk for HIV

Study shows link between inflammatory biomarkers and prevalence of CAD in HIV-infected men

CD4/CD8 ratio biomarker could help identify HIV-infected individuals at risk for heart disease

Scientists clarify mechanism of defective immune defense in G6PD patients

New study reports strains of chimpanzee-carried SIVs can infect human cells

Combining ART with immune-enhancing treatment may destabilize HIV reservoirs

Study results pave way to development of effective human vaccine against HIV

Researchers find distinct, non-identical differences among retroviruses

Topical delivery of AVR drug combination can provide complete protection against HIV

Autologous stem cell transplant safe, effective for HIV-associated lymphoma patients

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