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Clinical trial of monoclonal antibody for treating respiratory disease in COVID-19 patients begins

A clinical trial testing the safety and efficacy of an investigational monoclonal antibody for treating people who are hospitalized with respiratory disease and low blood oxygen due to infection with SARS-CoV-2, the virus that causes COVID-19, has begun.

13 Apr 2021

Tapeworm infection drug blocks SARS-CoV-2 damage in the lungs

New research published in the journal Nature found the presence of SARS-CoV-2 in the lungs resulted in abnormal pneumocytes and spike protein-mediated cell fusion. Their findings also showed that TMEM16F protein activation induces cell fusion. Therefore, drugs inhibiting the TMEM16F/Anoctamin6 calcium-activated ion channel, such as niclosamide, could serve as potential treatments for reducing the severity of COVID-19 infection.

12 Apr 2021

Tiny SARS-CoV-2 protein may have big implications for future COVID-19 treatments

A tiny protein of SARS-CoV-2, the coronavirus that gives rise to COVID-19, may have big implications for future treatments, according to a team of Penn State researchers.

9 Apr 2021

Gift boosts efforts to understand and combat rare cancers

Curing cancer has been the dream of countless doctors and researchers over the decades. Yet some types of cancer, whether because they affect relatively few people or lack influential advocates, receive less attention and funding than others.

9 Apr 2021

Pig brain atlas gives a more precise view of human brain

When scientists need to understand the effects of new infant formula ingredients on brain development, it's rarely possible for them to carry out initial safety studies with human subjects.

8 Apr 2021

Real-time imaging shines light on the coordination of neural stem cell activation

In all adult vertebrates, neural stem cells can be recruited to produce new neurons in the brain. However, little is known about these so-called "activation" processes.

8 Apr 2021

Mutations to autism-associated gene cause a cascade of problems in developing mouse brains

Damage to the autism-associated gene Dyrk1a, sets off a cascade of problems in developing mouse brains, resulting in abnormal growth-factor signaling, undergrowth of neurons, smaller-than-average brain size, and, eventually, autism-like behaviors, a new study from Scripps Research, Florida, finds.

8 Apr 2021

New grant to Harvard Medical School is boosting efforts to understand and combat rare cancers

7 Apr 2021

Scientists use cryo-electron microscopy to unravel how 'guardian' of the genome works

Scientists from the Genomic Integrity and Structural Biology Group led by Rafael Fernández-Leiro at the Spanish National Cancer Research Centre have discovered how certain proteins ensure the repair of errors introduced into the DNA during its replication.

6 Apr 2021

Researchers use single-cell RNA sequencing technologies to track cellular development in leaves

While developmental biologists have long researched this fundamental question, Stanford University biologist and HHMI investigator Dominique Bergmann's recent work on the plant Arabidopsis thaliana has uncovered surprising answers.

5 Apr 2021

New mini-microscope enables imaging of complex brain functions in freely moving mice

Researchers from the University of Minnesota Twin Cities College of Science and Engineering and Medical School have developed a unique head-mounted mini-microscope device that allows them to image complex brain functions of freely moving mice in real time over a period of more than 300 days.

5 Apr 2021

New RNA-sequencing method can help detect numerous modified small RNAs

A team led by a biomedical scientist at the University of California, Riverside, has developed a new RNA-sequencing method-- "Panoramic RNA Display by Overcoming RNA Modification Aborted Sequencing," or PANDORA-seq -- that can help discover numerous modified small RNAs that were previously undetectable.

5 Apr 2021

Olympus announces global image of the year award winners

Olympus unveiled the winners of their second Global Image of the Year Life Science Light Microscopy Award, an annual competition that recognizes the best in life science imaging.

From Evident Corporation - Life Sciences 5 Apr 2021

RNA-binding cylinders inhibit SARS-CoV-2 replication in vitro

Research led by Michael J. Hannon from the University of Birmingham, UK, finds metallo-supramolecular helicates (cylinders) binding to untranslated regions of SARS-CoV-2 suppresses viral replication. The untranslated regions (UTR) of the viral genome could serve as drug targets for antiviral treatment.

5 Apr 2021

Soft X-ray microscopy shows how viral pathogens penetrate human cells

How do viral pathogens succeed in penetrating human cells? Which cellular mechanisms do they use to multiply efficiently and, in doing so, how do they change the structure of their host cell? These questions are the focus of a pan-European research project called "Compact Cell-Imaging Device" (CoCID), in which Heidelberg scientists are playing a major role.

31 Mar 2021

Fat grafting shows potential to help cancer patients with radiation-induced skin injury

As cancer survival rates improve, more people are living with the aftereffects of cancer treatment. For some patients, these issues include chronic radiation-induced skin injury - which can lead to potentially severe cosmetic and functional problems.

30 Mar 2021

Researchers identify new targets for minimizing tooth sensitivity to cold

Researchers report in Science Advances that they have uncovered a new function for odontoblasts, the cells that form dentin, the shell beneath the tooth's enamel that encases the soft dental pulp containing nerves and blood vessels.

27 Mar 2021

UVA scientists identify a potential way to prevent heart attacks and strokes

Scientists at the University of Virginia School of Medicine have identified a potential way to head off heart attacks and strokes by strengthening the fibrous caps overlying atherosclerotic plaques that naturally accumulate inside our arteries.

27 Mar 2021

Grundium Press Release: 1000th Microscope Scanner

On March 24th, 2021 Grundium manufactured its 1000th microscope scanner.

From Grundium 26 Mar 2021

Bruker light-sheet microscopes at major comprehensive cancer center

Bruker Corporation (Nasdaq: BRKR), a leading supplier of single-plane illumination microscopy (SPIM) technology for research on live cells and cleared biological samples, today announced that two Luxendo MuVi™ and LCS SPIM™ light-sheet microscopes have been installed by Memorial Sloan Kettering Cancer Center (MSK).

From Bruker Nano Surfaces and Metrology 25 Mar 2021

Microscope News and Research

Clinical trial of monoclonal antibody for treating respiratory disease in COVID-19 patients begins

Tapeworm infection drug blocks SARS-CoV-2 damage in the lungs

Tiny SARS-CoV-2 protein may have big implications for future COVID-19 treatments

Gift boosts efforts to understand and combat rare cancers

Pig brain atlas gives a more precise view of human brain

Real-time imaging shines light on the coordination of neural stem cell activation

Mutations to autism-associated gene cause a cascade of problems in developing mouse brains

New grant to Harvard Medical School is boosting efforts to understand and combat rare cancers

Scientists use cryo-electron microscopy to unravel how 'guardian' of the genome works

Researchers use single-cell RNA sequencing technologies to track cellular development in leaves

New mini-microscope enables imaging of complex brain functions in freely moving mice

New RNA-sequencing method can help detect numerous modified small RNAs

Olympus announces global image of the year award winners

RNA-binding cylinders inhibit SARS-CoV-2 replication in vitro

Soft X-ray microscopy shows how viral pathogens penetrate human cells

Fat grafting shows potential to help cancer patients with radiation-induced skin injury

Researchers identify new targets for minimizing tooth sensitivity to cold

UVA scientists identify a potential way to prevent heart attacks and strokes

Grundium Press Release: 1000th Microscope Scanner

Bruker light-sheet microscopes at major comprehensive cancer center

Industry Focus eBook - Life Science Microscopy (2nd Edition) eBook

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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