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Immune killer cells use microptosis pathway to kill intracellular parasites

The immune system's killer cells deliver a tightly controlled, 3-phase knockout punch that kills intracellular parasites through a novel pathway that an international team led by researchers from the Program in Cellular and Molecular Medicine (PCMM) at Boston Children's Hospital have named "microptosis."

20 Jan 2016

Animal antibodies help identify diseased cells during immunohistology procedures

We all know it from biology lessons at school: Antibodies help us to ward off disease and are essential components of our immune system. What many people do not know is that physicians and scientists use animal antibodies to identify diseased or mutated cells.

20 Jan 2016

Adaptive, light-activated nanotherapy effective against drug-resistant bacteria

In the ever-escalating evolutionary battle with drug-resistant bacteria, humans may soon have a leg up thanks to adaptive, light-activated nanotherapy developed by researchers at the University of Colorado Boulder.

19 Jan 2016

Researchers suggest ways to make TB drugs more efficacious against mutations

Biophysicists have discovered why the bacteria that cause tuberculosis (TB) are naturally somewhat resistant to antibiotics known as fluoroquinolones. Their findings, based on mapping the detailed three-dimensional structure of the drugs interacting with an essential enzyme in the TB germ, also reveal why some TB drugs are more potent than others and suggest how drug developers can make fluoroquinolones more efficacious against mutations that make the lung disease drug resistant.

19 Jan 2016

New clinical imaging method may enable doctors to tackle lung infections

A new clinical imaging method developed in collaboration with a University of Exeter academic may enable doctors to tackle one of the main killers of patients with weakened immune systems sooner and more effectively.

19 Jan 2016

Antivirulence antibiotics could evade resistance longer than traditional antibiotics

We've all seen the headlines. "Man found to be shedding virulent strain of polio"; "Virulent flu strain in Europe hits the economy"; "Most virulent strain of E. coli ever seen contains DNA sequences from plague bacteria."

19 Jan 2016

Innovative microfiber pad could improve diagnosis of Urinary Tract Infection in infants and elderly patients

Contamination of urine samples from infants and the elderly is so common that physicians often needlessly prescribe broad-spectrum antibiotics prophylactically. Now, a team at The Hebrew University of Jerusalem's BioDesign: Medical Innovation program has developed an innovative microfiber pad that can save time and money in the collection of sterile samples.

18 Jan 2016

UM SOM to team up with industry to develop vaccine for preventing deadly bacterial infections

The Center for Vaccine Development at the University of Maryland School of Medicine will participate in a partnership with industry to develop a vaccine to prevent a group of deadly bacterial infections that occur commonly among hospital patients.

13 Jan 2016

Food preservative delivers one-two punch to cancer, antibiotic-resistant bacteria

Nisin, a naturally occurring food preservative that grows on dairy products, delivers a one-two punch to two of medicine's most lethal maladies: cancer and deadly, antibiotic-resistant bacteria.

12 Jan 2016

Malaysian scientists join forces with Harvard experts to help revolutionize lung disease treatment

Malaysian scientists are joining forces with Harvard University experts to help revolutionize the treatment of lung diseases -- the delivery of nanomedicine deep into places otherwise impossible to reach.

12 Jan 2016

Researcher seeks to identify probiotic mixes to treat Clostridium difficile infections

Antibiotics that fight infection can adversely affect the digestive tract and give destructive bacteria a chance to flourish, said assistant professor of veterinary and biomedical sciences Joy Scaria of South Dakota State University. His research seeks to identify probiotic mixes to treat intestinal infections, such as Clostridium difficile.

12 Jan 2016

UTA researchers map out chemical mechanism of key enzyme found in autism, Alzheimer's and Down syndrome

Biochemists at The University of Texas at Arlington are mapping the catalytic processes of sulfur-oxidizing enzymes to improve understanding of the chemical imbalances found in patients with autism, Alzheimer's disease and Down syndrome.

11 Jan 2016

New gene editing technique could hinder retinal degeneration in rats with inherited blindness

A new technique that has the potential to treat inherited diseases by removing genetic defects has been shown for the first time to hinder retinal degeneration in rats with a type of inherited blindness, according to a Cedars-Sinai study.

11 Jan 2016

Experts develop technologies for protecting drinking water

We place high demands on the quality of our drinking water. If pathogens or toxic substances found their way into the piping system, many people could become infected or injured very quickly. That's why this risk must be kept low. To do this, experts have developed technologies for a comprehensive monitoring, early warning and emergency management system.

7 Jan 2016

Common antibiotics can promote C. diff infections by killing off bile acid-altering microbes

New research from North Carolina State University and the University of Michigan finds that bile acids which are altered by bacteria normally living in the large intestine inhibit the growth of Clostridium difficile, or C. diff. C. diff is a harmful bacterium that can cause painful and sometimes fatal infections.

7 Jan 2016

Toxins in staphylococcus bacteria can help cancer cells gain control over healthy cells

Our skin is covered in millions of bacteria and most of them help keep us healthy. However, for patients with lymphoma, it may be a rather different story, as new research from the University of Copenhagen shows that toxins in the staphylococcus bacteria help cancer cells gain control over healthy cells.

6 Jan 2016

Study shows clear role of bacteria in modulating immune function in the lungs

Microbiota--the trillions of bacteria that co-exist in the body--regulate the ability of lung dendritic cells to generate immune responses, according to a study led by researchers from the Icahn School of Medicine at Mount Sinai, published online in the Journal of Experimental Medicine.

6 Jan 2016

Good bacteria can help inhibit growth of S. pneumoniae

A new study from the Forsyth Institute is helping to shed more light on the important connections among the diverse bacteria in our microbiome. According to research published in mBio, scientists at Forsyth, led by Dr. Katherine P. Lemon, along with their collaborator at Vanderbilt University, have demonstrated that a harmless bacterium found in the nose and on skin may negatively impact the growth of a pathogen that commonly causes middle ear infections in children and pneumonia in children and older adults.

6 Jan 2016

Nottingham researchers explore viruses that can destroy food poisoning bugs in the gut

Viruses that can seek and destroy food poisoning bugs in the gut are being investigated by researchers at The University of Nottingham, thanks to a prestigious new grant.

5 Jan 2016

Drug-microbe interactions may contribute to adverse effects, lessen effectiveness of NSAID

A nonsteroidal anti-inflammatory drug (NSAID) changed the composition and diversity of gut microbes, which in turn shaped how the drug is broken down and ultimately, cut its effectiveness, according to an animal study from the Perelman School of Medicine at the University of Pennsylvania.

5 Jan 2016

Bacteria News and Research

Immune killer cells use microptosis pathway to kill intracellular parasites

Animal antibodies help identify diseased cells during immunohistology procedures

Adaptive, light-activated nanotherapy effective against drug-resistant bacteria

Researchers suggest ways to make TB drugs more efficacious against mutations

New clinical imaging method may enable doctors to tackle lung infections

Antivirulence antibiotics could evade resistance longer than traditional antibiotics

Innovative microfiber pad could improve diagnosis of Urinary Tract Infection in infants and elderly patients

UM SOM to team up with industry to develop vaccine for preventing deadly bacterial infections

Food preservative delivers one-two punch to cancer, antibiotic-resistant bacteria

Malaysian scientists join forces with Harvard experts to help revolutionize lung disease treatment

Researcher seeks to identify probiotic mixes to treat Clostridium difficile infections

UTA researchers map out chemical mechanism of key enzyme found in autism, Alzheimer's and Down syndrome

New gene editing technique could hinder retinal degeneration in rats with inherited blindness

Experts develop technologies for protecting drinking water

Common antibiotics can promote C. diff infections by killing off bile acid-altering microbes

Toxins in staphylococcus bacteria can help cancer cells gain control over healthy cells

Study shows clear role of bacteria in modulating immune function in the lungs

Good bacteria can help inhibit growth of S. pneumoniae

Nottingham researchers explore viruses that can destroy food poisoning bugs in the gut

Drug-microbe interactions may contribute to adverse effects, lessen effectiveness of NSAID

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