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High fruit and vegetable intake linked to reduced risk of breast cancer

Women who eat a high amount of fruits and vegetables each day may have a lower risk of breast cancer, especially of aggressive tumors, than those who eat fewer fruits and vegetables, according to a new study led by researchers from Harvard T.H. Chan School of Public Health.

19 Jul 2018

Kite collaborates with Gadeta to develop novel gamma delta TCR therapies for various cancers

Kite, a Gilead Company, and Gadeta B.V., a privately-held company focused on the discovery and development of novel cancer immunotherapies based on gamma delta T cell receptors, have entered into a strategic collaboration to develop novel gamma delta TCR therapies in various cancers.

19 Jul 2018

Understanding triple-negative breast cancer to develop better treatments

Breast cancer affects 1 in 8 women in her lifetime. Among the various types, triple-negative breast cancer is the rarest and most aggressive – affecting about 15 percent of breast cancer patients. It is also the least studied.

19 Jul 2018

Study identifies RNA molecules that regulate male hormones in prostate cancer

In most cases of prostate cancer, tumor cell growth is stimulated by the action of male hormones, or androgens, such as testosterone and dihydrotestosterone.

19 Jul 2018

Sweetness depends on molecular interactions between specific sugars and water in saliva

A cranberry, honey or a candy bar - which tastes the sweetest? These foods contain sugars that humans can perceive differently.

19 Jul 2018

FDA grants approval for first breast cancer drug through 'Real-Time Oncology Review'

The U.S. Food and Drug Administration today approved Kisqali (ribociclib) in combination with an aromatase inhibitor for the treatment of pre/perimenopausal or postmenopausal women with hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative advanced or metastatic breast cancer, as initial endocrine-based therapy.

19 Jul 2018

High bitter-taste sensitivity linked to increased risk of cancer

High bitter-taste sensitivity is associated with a significantly increased risk of cancer in older British women, according to researchers who conducted a unique study of 5,500 women whose diet, lifestyle and health has been tracked for about 20 years.

18 Jul 2018

High-fat diet and systemic inflammation contribute to progression of prostate cancer

Osaka University-led study shows how a high-fat diet and systemic inflammation contribute to prostate cancer progression

18 Jul 2018

Homogenous BTK occupancy assay used in tirabrutinib clinical studies

In a new SLAS Discovery article, Helen Yu and a team of researchers at Gilead Sciences, Inc. present a time-resolved fluorescence resonance energy transfer-based Bruton's tyrosine kinase occupancy assay that can measure target engagement in peripheral blood mononuclear cells and in lymph-node and bone-marrow samples.

17 Jul 2018

Can-Fite BioPharma receives Australian and Chinese patents for new drug to treat erectile dysfunction

Can-Fite BioPharma Ltd., a biotechnology company advancing a pipeline of proprietary small molecule drugs that address liver diseases, inflammatory diseases and sexual dysfunction, today announced that the Australian and Chinese patent offices have granted the Company a patent for the utilization of A3 adenosine receptor ligands in the treatment of sexual dysfunction, in a patent (Australian, No. 2013301125ZL, Chinese No. 2013800472970) titled, "A3 adenosine receptor ligands for use in treatment of a sexual dysfunction."

17 Jul 2018

Immune T cells are built to react as fast as possible, shows study

Without T cells, we could not survive. They are a key component of our immune system and have highly sensitive receptors on their surface that can detect pathogens.

17 Jul 2018

Study delves into the role played by Protein Kinase C in synaptic plasticity

Inside the brain, is a complex symphony of perfectly coordinated signaling. Hundreds of different molecules amplify, modify and carry information from tiny synaptic compartments all the way through the entire length of a neuron.

17 Jul 2018

Olfactory receptors play pathophysiological role in all organs than merely smell perception

Numerous studies to date have shown that olfactory receptors are relevant not only for smell perception, but that they also play a significant physiological and pathophysiological role in all organs.

16 Jul 2018

Molecules formed when the body metabolizes omega-3 fatty acids may inhibit cancer

A class of molecules formed when the body metabolizes omega-3 fatty acids could inhibit cancer's growth and spread, University of Illinois researchers report in a new study in mice.

16 Jul 2018

Researchers find experimental compound to treat fibrotic diseases

Normal scar tissue forms to heal an internal wound and quietly retreats when the job is done. But in many common diseases - kidney, liver and lung fibrosis -- the scar tissue goes rogue and strangles vital organs. These diseases are largely untreatable and ultimately fatal.

13 Jul 2018

Receptor News and Research

High fruit and vegetable intake linked to reduced risk of breast cancer

Kite collaborates with Gadeta to develop novel gamma delta TCR therapies for various cancers

Understanding triple-negative breast cancer to develop better treatments

Study identifies RNA molecules that regulate male hormones in prostate cancer

Sweetness depends on molecular interactions between specific sugars and water in saliva

FDA grants approval for first breast cancer drug through 'Real-Time Oncology Review'

High bitter-taste sensitivity linked to increased risk of cancer

High-fat diet and systemic inflammation contribute to progression of prostate cancer

Homogenous BTK occupancy assay used in tirabrutinib clinical studies

Can-Fite BioPharma receives Australian and Chinese patents for new drug to treat erectile dysfunction

Immune T cells are built to react as fast as possible, shows study

Study delves into the role played by Protein Kinase C in synaptic plasticity

Olfactory receptors play pathophysiological role in all organs than merely smell perception

Molecules formed when the body metabolizes omega-3 fatty acids may inhibit cancer

Researchers find experimental compound to treat fibrotic diseases

Fighting cancer with engineered cancer cells

Scientists pinpoint new therapeutic targets for inflammation-associated colon cancer

Clinical trial results of tucatinib with T-DM1 shows promise in treating HER2+ breast cancer

Study could help explain how synapses may be made weaker or stronger

Newly discovered nanobody holds promise to advance targeted therapies for several diseases

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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